| Full name: metastasis associated 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 9112 | HGNC ID: HGNC:7410 | Ensembl Gene: ENSG00000182979 | OMIM ID: 603526 |
| Drug and gene relationship at DGIdb | |||
Expression of MTA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTA1 | 9112 | 211783_s_at | 0.9103 | 0.1384 | |
| GSE20347 | MTA1 | 9112 | 211783_s_at | 0.6312 | 0.0044 | |
| GSE23400 | MTA1 | 9112 | 211783_s_at | 0.8454 | 0.0000 | |
| GSE26886 | MTA1 | 9112 | 211783_s_at | 0.8774 | 0.0016 | |
| GSE29001 | MTA1 | 9112 | 211783_s_at | 0.2356 | 0.6072 | |
| GSE38129 | MTA1 | 9112 | 211783_s_at | 0.5759 | 0.0006 | |
| GSE45670 | MTA1 | 9112 | 211783_s_at | 0.3133 | 0.1234 | |
| GSE53622 | MTA1 | 9112 | 88780 | 0.4358 | 0.0000 | |
| GSE53624 | MTA1 | 9112 | 88780 | 0.4909 | 0.0000 | |
| GSE63941 | MTA1 | 9112 | 211783_s_at | 0.5276 | 0.2959 | |
| GSE77861 | MTA1 | 9112 | 211783_s_at | 0.7002 | 0.1015 | |
| GSE97050 | MTA1 | 9112 | A_33_P3359306 | 0.0410 | 0.9041 | |
| SRP007169 | MTA1 | 9112 | RNAseq | 0.5238 | 0.2466 | |
| SRP008496 | MTA1 | 9112 | RNAseq | 0.2598 | 0.4160 | |
| SRP064894 | MTA1 | 9112 | RNAseq | 0.6236 | 0.0006 | |
| SRP133303 | MTA1 | 9112 | RNAseq | 0.3822 | 0.0016 | |
| SRP159526 | MTA1 | 9112 | RNAseq | 1.0483 | 0.0333 | |
| SRP193095 | MTA1 | 9112 | RNAseq | 0.8527 | 0.0000 | |
| SRP219564 | MTA1 | 9112 | RNAseq | 0.5704 | 0.0410 | |
| TCGA | MTA1 | 9112 | RNAseq | 0.1423 | 0.0029 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MTA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MTA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTA1 | 9112 | 11 | 3 | 16 | |
| GSE20123 | MTA1 | 9112 | 10 | 2 | 18 | |
| GSE43470 | MTA1 | 9112 | 5 | 3 | 35 | |
| GSE46452 | MTA1 | 9112 | 18 | 4 | 37 | |
| GSE47630 | MTA1 | 9112 | 10 | 10 | 20 | |
| GSE54993 | MTA1 | 9112 | 4 | 11 | 55 | |
| GSE54994 | MTA1 | 9112 | 21 | 4 | 28 | |
| GSE60625 | MTA1 | 9112 | 0 | 2 | 9 | |
| GSE74703 | MTA1 | 9112 | 4 | 3 | 29 | |
| GSE74704 | MTA1 | 9112 | 5 | 2 | 13 | |
| TCGA | MTA1 | 9112 | 31 | 18 | 47 |
Total number of gains: 119; Total number of losses: 62; Total Number of normals: 307.
Somatic mutations of MTA1:
Generating mutation plots.
Highly correlated genes for MTA1:
Showing top 20/378 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTA1 | ACYP1 | 0.675742 | 8 | 0 | 7 |
| MTA1 | DDOST | 0.650072 | 3 | 0 | 3 |
| MTA1 | TELO2 | 0.645388 | 4 | 0 | 3 |
| MTA1 | ZNF114 | 0.641543 | 5 | 0 | 5 |
| MTA1 | CDCA7L | 0.633773 | 6 | 0 | 5 |
| MTA1 | TRMT2A | 0.629933 | 4 | 0 | 4 |
| MTA1 | VRK1 | 0.624541 | 9 | 0 | 8 |
| MTA1 | ERH | 0.623635 | 10 | 0 | 7 |
| MTA1 | FSTL3 | 0.619063 | 4 | 0 | 3 |
| MTA1 | ZRANB3 | 0.617923 | 5 | 0 | 4 |
| MTA1 | IFT43 | 0.616 | 5 | 0 | 4 |
| MTA1 | ZC3HAV1L | 0.614172 | 3 | 0 | 3 |
| MTA1 | INTS3 | 0.61135 | 7 | 0 | 4 |
| MTA1 | WDR54 | 0.609539 | 5 | 0 | 4 |
| MTA1 | DOHH | 0.609377 | 4 | 0 | 3 |
| MTA1 | CAD | 0.607467 | 8 | 0 | 6 |
| MTA1 | DMRTC2 | 0.606057 | 3 | 0 | 3 |
| MTA1 | CEP131 | 0.599723 | 8 | 0 | 7 |
| MTA1 | PLEKHG4B | 0.598441 | 6 | 0 | 5 |
| MTA1 | AHSA1 | 0.597442 | 9 | 0 | 7 |
For details and further investigation, click here
