| Full name: ataxin 7 like 3 | Alias Symbol: DKFZp761G2113 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 56970 | HGNC ID: HGNC:25416 | Ensembl Gene: ENSG00000087152 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ATXN7L3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATXN7L3 | 56970 | 224969_at | 0.4296 | 0.0997 | |
| GSE26886 | ATXN7L3 | 56970 | 224969_at | -0.1723 | 0.1093 | |
| GSE45670 | ATXN7L3 | 56970 | 224969_at | 0.1934 | 0.0297 | |
| GSE53622 | ATXN7L3 | 56970 | 155403 | -0.0173 | 0.8202 | |
| GSE53624 | ATXN7L3 | 56970 | 155403 | 0.0187 | 0.7612 | |
| GSE63941 | ATXN7L3 | 56970 | 224969_at | 0.4732 | 0.0115 | |
| GSE77861 | ATXN7L3 | 56970 | 224969_at | 0.1152 | 0.5173 | |
| GSE97050 | ATXN7L3 | 56970 | A_23_P421935 | 0.2814 | 0.3820 | |
| SRP007169 | ATXN7L3 | 56970 | RNAseq | -1.0684 | 0.0008 | |
| SRP008496 | ATXN7L3 | 56970 | RNAseq | -0.8619 | 0.0000 | |
| SRP064894 | ATXN7L3 | 56970 | RNAseq | 0.0761 | 0.6210 | |
| SRP133303 | ATXN7L3 | 56970 | RNAseq | -0.0455 | 0.7643 | |
| SRP159526 | ATXN7L3 | 56970 | RNAseq | -0.2053 | 0.3794 | |
| SRP193095 | ATXN7L3 | 56970 | RNAseq | -0.1075 | 0.1748 | |
| SRP219564 | ATXN7L3 | 56970 | RNAseq | -0.1305 | 0.6807 | |
| TCGA | ATXN7L3 | 56970 | RNAseq | 0.1094 | 0.0182 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ATXN7L3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATXN7L3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATXN7L3 | 56970 | 5 | 2 | 23 | |
| GSE20123 | ATXN7L3 | 56970 | 5 | 2 | 23 | |
| GSE43470 | ATXN7L3 | 56970 | 1 | 2 | 40 | |
| GSE46452 | ATXN7L3 | 56970 | 32 | 0 | 27 | |
| GSE47630 | ATXN7L3 | 56970 | 9 | 0 | 31 | |
| GSE54993 | ATXN7L3 | 56970 | 3 | 4 | 63 | |
| GSE54994 | ATXN7L3 | 56970 | 8 | 5 | 40 | |
| GSE60625 | ATXN7L3 | 56970 | 4 | 0 | 7 | |
| GSE74703 | ATXN7L3 | 56970 | 1 | 1 | 34 | |
| GSE74704 | ATXN7L3 | 56970 | 3 | 1 | 16 | |
| TCGA | ATXN7L3 | 56970 | 23 | 7 | 66 |
Total number of gains: 94; Total number of losses: 24; Total Number of normals: 370.
Somatic mutations of ATXN7L3:
Generating mutation plots.
Highly correlated genes for ATXN7L3:
Showing top 20/405 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATXN7L3 | ILF2 | 0.734842 | 3 | 0 | 3 |
| ATXN7L3 | DDOST | 0.726188 | 3 | 0 | 3 |
| ATXN7L3 | XPO6 | 0.719575 | 3 | 0 | 3 |
| ATXN7L3 | TMEM11 | 0.718711 | 3 | 0 | 3 |
| ATXN7L3 | ARMC6 | 0.709041 | 3 | 0 | 3 |
| ATXN7L3 | SLC33A1 | 0.695713 | 3 | 0 | 3 |
| ATXN7L3 | PNPO | 0.692291 | 4 | 0 | 3 |
| ATXN7L3 | EPHB1 | 0.691835 | 3 | 0 | 3 |
| ATXN7L3 | PNO1 | 0.691687 | 3 | 0 | 3 |
| ATXN7L3 | TRIP13 | 0.687057 | 3 | 0 | 3 |
| ATXN7L3 | DDX28 | 0.685105 | 3 | 0 | 3 |
| ATXN7L3 | FOXRED2 | 0.68373 | 3 | 0 | 3 |
| ATXN7L3 | FOXM1 | 0.678172 | 3 | 0 | 3 |
| ATXN7L3 | CCNE1 | 0.677918 | 4 | 0 | 4 |
| ATXN7L3 | SLC25A39 | 0.673073 | 8 | 0 | 7 |
| ATXN7L3 | DOLPP1 | 0.668636 | 5 | 0 | 5 |
| ATXN7L3 | PRKD2 | 0.667321 | 4 | 0 | 3 |
| ATXN7L3 | TRIM28 | 0.665486 | 5 | 0 | 4 |
| ATXN7L3 | IL2RG | 0.664607 | 3 | 0 | 3 |
| ATXN7L3 | NUSAP1 | 0.663948 | 4 | 0 | 3 |
For details and further investigation, click here
