| Full name: mitochondrial ribosome associated GTPase 2 | Alias Symbol: FLJ10741|dJ1005F21.2|ObgH1 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 26164 | HGNC ID: HGNC:16239 | Ensembl Gene: ENSG00000101181 | OMIM ID: 610919 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MTG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MTG2 | 26164 | 226606_s_at | 1.1890 | 0.0997 | |
| GSE26886 | MTG2 | 26164 | 226606_s_at | 1.0533 | 0.0042 | |
| GSE45670 | MTG2 | 26164 | 226598_s_at | 0.2032 | 0.0199 | |
| GSE53622 | MTG2 | 26164 | 156596 | 0.5539 | 0.0000 | |
| GSE53624 | MTG2 | 26164 | 156596 | 0.5698 | 0.0000 | |
| GSE63941 | MTG2 | 26164 | 226606_s_at | 0.6169 | 0.2951 | |
| GSE77861 | MTG2 | 26164 | 226598_s_at | 0.0797 | 0.6380 | |
| SRP007169 | MTG2 | 26164 | RNAseq | 0.0556 | 0.9068 | |
| SRP008496 | MTG2 | 26164 | RNAseq | 0.1983 | 0.5934 | |
| SRP064894 | MTG2 | 26164 | RNAseq | 0.6744 | 0.0000 | |
| SRP133303 | MTG2 | 26164 | RNAseq | 0.3187 | 0.0003 | |
| SRP159526 | MTG2 | 26164 | RNAseq | 0.2707 | 0.4423 | |
| SRP193095 | MTG2 | 26164 | RNAseq | 0.4456 | 0.0000 | |
| SRP219564 | MTG2 | 26164 | RNAseq | 0.7199 | 0.0134 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MTG2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MTG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MTG2 | 26164 | 13 | 2 | 15 | |
| GSE20123 | MTG2 | 26164 | 14 | 2 | 14 | |
| GSE43470 | MTG2 | 26164 | 11 | 1 | 31 | |
| GSE46452 | MTG2 | 26164 | 35 | 0 | 24 | |
| GSE47630 | MTG2 | 26164 | 25 | 1 | 14 | |
| GSE54993 | MTG2 | 26164 | 0 | 17 | 53 | |
| GSE54994 | MTG2 | 26164 | 29 | 0 | 24 | |
| GSE60625 | MTG2 | 26164 | 0 | 0 | 11 | |
| GSE74703 | MTG2 | 26164 | 10 | 0 | 26 | |
| GSE74704 | MTG2 | 26164 | 11 | 0 | 9 | |
| TCGA | MTG2 | 26164 | 43 | 4 | 49 |
Total number of gains: 191; Total number of losses: 27; Total Number of normals: 270.
Somatic mutations of MTG2:
Generating mutation plots.
Highly correlated genes for MTG2:
Showing top 20/221 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MTG2 | NUDCD1 | 0.675658 | 3 | 0 | 3 |
| MTG2 | CEP131 | 0.666483 | 3 | 0 | 3 |
| MTG2 | MFAP2 | 0.662581 | 4 | 0 | 4 |
| MTG2 | ASAP1-IT1 | 0.655915 | 3 | 0 | 3 |
| MTG2 | PSMB1 | 0.654101 | 3 | 0 | 3 |
| MTG2 | HAX1 | 0.647919 | 3 | 0 | 3 |
| MTG2 | ZGPAT | 0.647621 | 4 | 0 | 4 |
| MTG2 | ACP2 | 0.645445 | 3 | 0 | 3 |
| MTG2 | FANCE | 0.645427 | 3 | 0 | 3 |
| MTG2 | SLC25A32 | 0.638143 | 4 | 0 | 4 |
| MTG2 | P4HA1 | 0.63661 | 3 | 0 | 3 |
| MTG2 | INTS8 | 0.628865 | 4 | 0 | 3 |
| MTG2 | MPLKIP | 0.628595 | 3 | 0 | 3 |
| MTG2 | CTHRC1 | 0.627676 | 4 | 0 | 4 |
| MTG2 | ASPH | 0.627141 | 3 | 0 | 3 |
| MTG2 | BRIX1 | 0.621847 | 4 | 0 | 4 |
| MTG2 | SLC27A3 | 0.621561 | 3 | 0 | 3 |
| MTG2 | ZNF133 | 0.620843 | 3 | 0 | 3 |
| MTG2 | CENPQ | 0.618669 | 3 | 0 | 3 |
| MTG2 | TGS1 | 0.61675 | 4 | 0 | 3 |
For details and further investigation, click here
