| Full name: mucin 4, cell surface associated | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q29 | ||
| Entrez ID: 4585 | HGNC ID: HGNC:7514 | Ensembl Gene: ENSG00000145113 | OMIM ID: 158372 |
| Drug and gene relationship at DGIdb | |||
Expression of MUC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MUC4 | 4585 | 217109_at | -0.2918 | 0.9218 | |
| GSE20347 | MUC4 | 4585 | 217109_at | 0.0827 | 0.9356 | |
| GSE23400 | MUC4 | 4585 | 217109_at | -0.5509 | 0.1477 | |
| GSE26886 | MUC4 | 4585 | 217109_at | -3.7698 | 0.0000 | |
| GSE29001 | MUC4 | 4585 | 217109_at | -0.8019 | 0.5622 | |
| GSE38129 | MUC4 | 4585 | 217109_at | 0.1786 | 0.8187 | |
| GSE45670 | MUC4 | 4585 | 217109_at | 2.7483 | 0.0023 | |
| GSE53622 | MUC4 | 4585 | 12267 | -0.0988 | 0.8010 | |
| GSE53624 | MUC4 | 4585 | 12267 | -0.5633 | 0.0027 | |
| GSE63941 | MUC4 | 4585 | 204895_x_at | 0.7860 | 0.4706 | |
| GSE77861 | MUC4 | 4585 | 217109_at | -1.5168 | 0.3093 | |
| GSE97050 | MUC4 | 4585 | A_24_P239176 | 2.1343 | 0.1297 | |
| SRP007169 | MUC4 | 4585 | RNAseq | -1.1217 | 0.5035 | |
| SRP064894 | MUC4 | 4585 | RNAseq | -1.5168 | 0.0113 | |
| SRP133303 | MUC4 | 4585 | RNAseq | 0.0728 | 0.9334 | |
| SRP159526 | MUC4 | 4585 | RNAseq | -3.3230 | 0.0000 | |
| SRP193095 | MUC4 | 4585 | RNAseq | -1.0026 | 0.0579 | |
| SRP219564 | MUC4 | 4585 | RNAseq | 0.2809 | 0.8240 | |
| TCGA | MUC4 | 4585 | RNAseq | 0.4909 | 0.1825 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by MUC4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MUC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MUC4 | 4585 | 22 | 0 | 8 | |
| GSE20123 | MUC4 | 4585 | 22 | 0 | 8 | |
| GSE43470 | MUC4 | 4585 | 21 | 0 | 22 | |
| GSE46452 | MUC4 | 4585 | 19 | 1 | 39 | |
| GSE47630 | MUC4 | 4585 | 27 | 2 | 11 | |
| GSE54993 | MUC4 | 4585 | 1 | 22 | 47 | |
| GSE54994 | MUC4 | 4585 | 41 | 0 | 12 | |
| GSE60625 | MUC4 | 4585 | 0 | 6 | 5 | |
| GSE74703 | MUC4 | 4585 | 19 | 0 | 17 | |
| GSE74704 | MUC4 | 4585 | 14 | 0 | 6 | |
| TCGA | MUC4 | 4585 | 77 | 0 | 19 |
Total number of gains: 263; Total number of losses: 31; Total Number of normals: 194.
Somatic mutations of MUC4:
Generating mutation plots.
Highly correlated genes for MUC4:
Showing top 20/208 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MUC4 | ANKRD13A | 0.719074 | 3 | 0 | 3 |
| MUC4 | CLPX | 0.702762 | 3 | 0 | 3 |
| MUC4 | GFPT1 | 0.694966 | 3 | 0 | 3 |
| MUC4 | TET2 | 0.677483 | 3 | 0 | 3 |
| MUC4 | MSL3 | 0.663301 | 3 | 0 | 3 |
| MUC4 | CHIC2 | 0.659026 | 3 | 0 | 3 |
| MUC4 | FUNDC1 | 0.654732 | 3 | 0 | 3 |
| MUC4 | CYFIP1 | 0.652093 | 3 | 0 | 3 |
| MUC4 | TNKS2 | 0.650258 | 3 | 0 | 3 |
| MUC4 | MUC20 | 0.645107 | 8 | 0 | 7 |
| MUC4 | FAR1 | 0.644109 | 3 | 0 | 3 |
| MUC4 | PDIK1L | 0.643575 | 3 | 0 | 3 |
| MUC4 | ERI2 | 0.64273 | 4 | 0 | 3 |
| MUC4 | MMAB | 0.639156 | 3 | 0 | 3 |
| MUC4 | NCOA4 | 0.629144 | 3 | 0 | 3 |
| MUC4 | SYPL1 | 0.629 | 4 | 0 | 3 |
| MUC4 | SOX21-AS1 | 0.626154 | 5 | 0 | 3 |
| MUC4 | MYB | 0.625811 | 3 | 0 | 3 |
| MUC4 | P4HB | 0.622846 | 4 | 0 | 3 |
| MUC4 | TM9SF3 | 0.620163 | 3 | 0 | 3 |
For details and further investigation, click here
