| Full name: myosin VB | Alias Symbol: KIAA1119 | ||
| Type: protein-coding gene | Cytoband: 18q | ||
| Entrez ID: 4645 | HGNC ID: HGNC:7603 | Ensembl Gene: ENSG00000167306 | OMIM ID: 606540 |
| Drug and gene relationship at DGIdb | |||
Expression of MYO5B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYO5B | 4645 | 225301_s_at | -1.3710 | 0.1863 | |
| GSE26886 | MYO5B | 4645 | 225301_s_at | -1.4513 | 0.0000 | |
| GSE45670 | MYO5B | 4645 | 225301_s_at | -0.5251 | 0.0605 | |
| GSE53622 | MYO5B | 4645 | 4384 | -1.4515 | 0.0000 | |
| GSE53624 | MYO5B | 4645 | 4384 | -2.0239 | 0.0000 | |
| GSE63941 | MYO5B | 4645 | 225301_s_at | 3.2833 | 0.0012 | |
| GSE77861 | MYO5B | 4645 | 225301_s_at | -1.2982 | 0.0206 | |
| GSE97050 | MYO5B | 4645 | A_33_P3317979 | -0.0817 | 0.7533 | |
| SRP007169 | MYO5B | 4645 | RNAseq | -2.0607 | 0.0000 | |
| SRP008496 | MYO5B | 4645 | RNAseq | -1.6935 | 0.0000 | |
| SRP064894 | MYO5B | 4645 | RNAseq | -2.6342 | 0.0000 | |
| SRP133303 | MYO5B | 4645 | RNAseq | -1.3731 | 0.0000 | |
| SRP159526 | MYO5B | 4645 | RNAseq | -2.2102 | 0.0000 | |
| SRP193095 | MYO5B | 4645 | RNAseq | -1.7781 | 0.0000 | |
| SRP219564 | MYO5B | 4645 | RNAseq | -2.2261 | 0.0104 | |
| TCGA | MYO5B | 4645 | RNAseq | -0.2844 | 0.0265 |
Upregulated datasets: 1; Downregulated datasets: 11.
Survival by MYO5B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYO5B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYO5B | 4645 | 1 | 9 | 20 | |
| GSE20123 | MYO5B | 4645 | 1 | 9 | 20 | |
| GSE43470 | MYO5B | 4645 | 0 | 4 | 39 | |
| GSE46452 | MYO5B | 4645 | 1 | 26 | 32 | |
| GSE47630 | MYO5B | 4645 | 5 | 20 | 15 | |
| GSE54993 | MYO5B | 4645 | 9 | 0 | 61 | |
| GSE54994 | MYO5B | 4645 | 1 | 17 | 35 | |
| GSE60625 | MYO5B | 4645 | 0 | 4 | 7 | |
| GSE74703 | MYO5B | 4645 | 0 | 4 | 32 | |
| GSE74704 | MYO5B | 4645 | 1 | 6 | 13 | |
| TCGA | MYO5B | 4645 | 10 | 43 | 43 |
Total number of gains: 29; Total number of losses: 142; Total Number of normals: 317.
Somatic mutations of MYO5B:
Generating mutation plots.
Highly correlated genes for MYO5B:
Showing top 20/964 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYO5B | GDPD3 | 0.83398 | 7 | 0 | 7 |
| MYO5B | EPS8L2 | 0.831711 | 7 | 0 | 7 |
| MYO5B | PRSS2 | 0.830078 | 5 | 0 | 5 |
| MYO5B | CES2 | 0.825057 | 5 | 0 | 5 |
| MYO5B | SCNN1B | 0.823432 | 7 | 0 | 7 |
| MYO5B | PRSS27 | 0.816372 | 8 | 0 | 8 |
| MYO5B | VPS4B | 0.814143 | 6 | 0 | 6 |
| MYO5B | RANBP9 | 0.806215 | 6 | 0 | 6 |
| MYO5B | CHP1 | 0.802272 | 6 | 0 | 6 |
| MYO5B | CLIC3 | 0.802055 | 5 | 0 | 4 |
| MYO5B | SULT2B1 | 0.801775 | 6 | 0 | 6 |
| MYO5B | MALL | 0.80082 | 7 | 0 | 7 |
| MYO5B | VSIG10L | 0.796803 | 7 | 0 | 7 |
| MYO5B | USP6NL | 0.795902 | 6 | 0 | 6 |
| MYO5B | TIAM1 | 0.794739 | 7 | 0 | 7 |
| MYO5B | PADI1 | 0.794247 | 5 | 0 | 5 |
| MYO5B | SNORA68 | 0.793301 | 4 | 0 | 4 |
| MYO5B | SPINK7 | 0.79201 | 7 | 0 | 7 |
| MYO5B | EPS8L1 | 0.790211 | 8 | 0 | 8 |
| MYO5B | EVPL | 0.789991 | 8 | 0 | 8 |
For details and further investigation, click here
