| Full name: myelin regulatory factor | Alias Symbol: Ndt80|pqn-47|MRF | ||
| Type: protein-coding gene | Cytoband: 11q12.2 | ||
| Entrez ID: 745 | HGNC ID: HGNC:1181 | Ensembl Gene: ENSG00000124920 | OMIM ID: 608329 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MYRF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYRF | 745 | 204073_s_at | -0.3858 | 0.4970 | |
| GSE20347 | MYRF | 745 | 204073_s_at | -0.1993 | 0.3504 | |
| GSE23400 | MYRF | 745 | 204073_s_at | -0.4172 | 0.0000 | |
| GSE26886 | MYRF | 745 | 204073_s_at | -0.0584 | 0.8714 | |
| GSE29001 | MYRF | 745 | 204073_s_at | -0.3407 | 0.1330 | |
| GSE38129 | MYRF | 745 | 204073_s_at | -0.4599 | 0.0529 | |
| GSE45670 | MYRF | 745 | 217462_at | 0.0915 | 0.3581 | |
| GSE53622 | MYRF | 745 | 62285 | -0.3314 | 0.0532 | |
| GSE53624 | MYRF | 745 | 62285 | -0.4500 | 0.0001 | |
| GSE63941 | MYRF | 745 | 204073_s_at | 0.7446 | 0.2315 | |
| GSE77861 | MYRF | 745 | 217462_at | -0.2272 | 0.1432 | |
| SRP007169 | MYRF | 745 | RNAseq | -0.5388 | 0.3659 | |
| SRP064894 | MYRF | 745 | RNAseq | -0.8168 | 0.0684 | |
| SRP133303 | MYRF | 745 | RNAseq | -0.9041 | 0.0000 | |
| SRP159526 | MYRF | 745 | RNAseq | 1.1390 | 0.0752 | |
| SRP193095 | MYRF | 745 | RNAseq | -0.9694 | 0.0486 | |
| SRP219564 | MYRF | 745 | RNAseq | -0.7961 | 0.1775 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MYRF expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MYRF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYRF | 745 | 5 | 5 | 20 | |
| GSE20123 | MYRF | 745 | 5 | 5 | 20 | |
| GSE43470 | MYRF | 745 | 2 | 6 | 35 | |
| GSE46452 | MYRF | 745 | 8 | 4 | 47 | |
| GSE47630 | MYRF | 745 | 3 | 8 | 29 | |
| GSE54993 | MYRF | 745 | 3 | 0 | 67 | |
| GSE54994 | MYRF | 745 | 4 | 8 | 41 | |
| GSE60625 | MYRF | 745 | 0 | 3 | 8 | |
| GSE74703 | MYRF | 745 | 2 | 3 | 31 | |
| GSE74704 | MYRF | 745 | 4 | 3 | 13 | |
| TCGA | MYRF | 745 | 14 | 10 | 72 |
Total number of gains: 50; Total number of losses: 55; Total Number of normals: 383.
Somatic mutations of MYRF:
Generating mutation plots.
Highly correlated genes for MYRF:
Showing top 20/224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYRF | RALGPS2 | 0.686683 | 3 | 0 | 3 |
| MYRF | FAM3D | 0.662892 | 3 | 0 | 3 |
| MYRF | SMAGP | 0.661719 | 3 | 0 | 3 |
| MYRF | CIDEA | 0.658489 | 3 | 0 | 3 |
| MYRF | FLG | 0.658456 | 4 | 0 | 4 |
| MYRF | GFOD2 | 0.653517 | 3 | 0 | 3 |
| MYRF | RAB37 | 0.649527 | 3 | 0 | 3 |
| MYRF | SH3GLB1 | 0.648413 | 3 | 0 | 3 |
| MYRF | OSTF1 | 0.642003 | 3 | 0 | 3 |
| MYRF | ESPL1 | 0.641599 | 4 | 0 | 4 |
| MYRF | SLC13A4 | 0.636137 | 4 | 0 | 4 |
| MYRF | IL36A | 0.635594 | 4 | 0 | 4 |
| MYRF | TRIP10 | 0.634559 | 4 | 0 | 4 |
| MYRF | MAP2K7 | 0.63024 | 3 | 0 | 3 |
| MYRF | WWC1 | 0.629543 | 5 | 0 | 4 |
| MYRF | ANXA9 | 0.625731 | 4 | 0 | 4 |
| MYRF | N4BP3 | 0.625704 | 5 | 0 | 4 |
| MYRF | MMEL1 | 0.624657 | 5 | 0 | 4 |
| MYRF | SH3GL1 | 0.62249 | 4 | 0 | 4 |
| MYRF | MTMR3 | 0.622377 | 4 | 0 | 4 |
For details and further investigation, click here
