| Full name: carboxypeptidase A6 | Alias Symbol: CPAH | ||
| Type: protein-coding gene | Cytoband: 8q13.2 | ||
| Entrez ID: 57094 | HGNC ID: HGNC:17245 | Ensembl Gene: ENSG00000165078 | OMIM ID: 609562 |
| Drug and gene relationship at DGIdb | |||
Expression of CPA6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CPA6 | 57094 | 1552511_a_at | -0.1611 | 0.8899 | |
| GSE26886 | CPA6 | 57094 | 1552511_a_at | 0.1953 | 0.4396 | |
| GSE45670 | CPA6 | 57094 | 1552511_a_at | 0.2414 | 0.6387 | |
| GSE53622 | CPA6 | 57094 | 65106 | -0.8187 | 0.0028 | |
| GSE53624 | CPA6 | 57094 | 65106 | -1.4513 | 0.0000 | |
| GSE63941 | CPA6 | 57094 | 1552511_a_at | 0.2588 | 0.8426 | |
| GSE77861 | CPA6 | 57094 | 1552511_a_at | -0.1246 | 0.4555 | |
| GSE97050 | CPA6 | 57094 | A_24_P4170 | 0.5767 | 0.3360 | |
| SRP007169 | CPA6 | 57094 | RNAseq | 1.3556 | 0.0805 | |
| SRP133303 | CPA6 | 57094 | RNAseq | 0.6451 | 0.1295 | |
| SRP159526 | CPA6 | 57094 | RNAseq | -2.0136 | 0.0013 | |
| SRP219564 | CPA6 | 57094 | RNAseq | 0.3868 | 0.6720 | |
| TCGA | CPA6 | 57094 | RNAseq | 0.3617 | 0.5603 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by CPA6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CPA6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CPA6 | 57094 | 15 | 1 | 14 | |
| GSE20123 | CPA6 | 57094 | 16 | 1 | 13 | |
| GSE43470 | CPA6 | 57094 | 15 | 3 | 25 | |
| GSE46452 | CPA6 | 57094 | 20 | 2 | 37 | |
| GSE47630 | CPA6 | 57094 | 23 | 1 | 16 | |
| GSE54993 | CPA6 | 57094 | 1 | 18 | 51 | |
| GSE54994 | CPA6 | 57094 | 30 | 0 | 23 | |
| GSE60625 | CPA6 | 57094 | 0 | 4 | 7 | |
| GSE74703 | CPA6 | 57094 | 13 | 2 | 21 | |
| GSE74704 | CPA6 | 57094 | 11 | 0 | 9 | |
| TCGA | CPA6 | 57094 | 50 | 4 | 42 |
Total number of gains: 194; Total number of losses: 36; Total Number of normals: 258.
Somatic mutations of CPA6:
Generating mutation plots.
Highly correlated genes for CPA6:
Showing top 20/70 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CPA6 | MZF1 | 0.746665 | 3 | 0 | 3 |
| CPA6 | USP9Y | 0.736813 | 3 | 0 | 3 |
| CPA6 | EIF3E | 0.69454 | 3 | 0 | 3 |
| CPA6 | ZRANB2 | 0.689069 | 3 | 0 | 3 |
| CPA6 | SURF1 | 0.672975 | 3 | 0 | 3 |
| CPA6 | CLK4 | 0.664824 | 3 | 0 | 3 |
| CPA6 | PLEKHA4 | 0.659966 | 3 | 0 | 3 |
| CPA6 | PLCB2 | 0.650613 | 3 | 0 | 3 |
| CPA6 | SLITRK6 | 0.647887 | 3 | 0 | 3 |
| CPA6 | KLRC3 | 0.64486 | 3 | 0 | 3 |
| CPA6 | SIRPG | 0.642877 | 3 | 0 | 3 |
| CPA6 | SPATA7 | 0.633995 | 3 | 0 | 3 |
| CPA6 | KSR2 | 0.633778 | 3 | 0 | 3 |
| CPA6 | SERTAD1 | 0.625139 | 3 | 0 | 3 |
| CPA6 | RPL34 | 0.623051 | 3 | 0 | 3 |
| CPA6 | TMEM65 | 0.62028 | 4 | 0 | 4 |
| CPA6 | MED24 | 0.619884 | 3 | 0 | 3 |
| CPA6 | MARK3 | 0.617241 | 3 | 0 | 3 |
| CPA6 | ACSF2 | 0.614752 | 4 | 0 | 3 |
| CPA6 | BIN2 | 0.612141 | 3 | 0 | 3 |
For details and further investigation, click here
