| Full name: N-deacetylase and N-sulfotransferase 2 | Alias Symbol: NST2|HSST2 | ||
| Type: protein-coding gene | Cytoband: 10q22.2 | ||
| Entrez ID: 8509 | HGNC ID: HGNC:7681 | Ensembl Gene: ENSG00000166507 | OMIM ID: 603268 |
| Drug and gene relationship at DGIdb | |||
Expression of NDST2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDST2 | 8509 | 203916_at | -0.2279 | 0.5589 | |
| GSE20347 | NDST2 | 8509 | 203916_at | -0.2277 | 0.0052 | |
| GSE23400 | NDST2 | 8509 | 203916_at | -0.3456 | 0.0000 | |
| GSE26886 | NDST2 | 8509 | 203916_at | -0.4308 | 0.0455 | |
| GSE29001 | NDST2 | 8509 | 203916_at | -0.5688 | 0.0002 | |
| GSE38129 | NDST2 | 8509 | 203916_at | -0.1745 | 0.0547 | |
| GSE45670 | NDST2 | 8509 | 203916_at | -0.2042 | 0.0944 | |
| GSE63941 | NDST2 | 8509 | 203916_at | -0.5136 | 0.0904 | |
| GSE77861 | NDST2 | 8509 | 203916_at | -0.2771 | 0.0095 | |
| GSE97050 | NDST2 | 8509 | A_33_P3329255 | -0.2637 | 0.2533 | |
| SRP007169 | NDST2 | 8509 | RNAseq | -1.5307 | 0.0009 | |
| SRP008496 | NDST2 | 8509 | RNAseq | -0.8946 | 0.0487 | |
| SRP064894 | NDST2 | 8509 | RNAseq | -0.7696 | 0.0000 | |
| SRP133303 | NDST2 | 8509 | RNAseq | -0.6995 | 0.0000 | |
| SRP159526 | NDST2 | 8509 | RNAseq | -0.4788 | 0.1661 | |
| SRP193095 | NDST2 | 8509 | RNAseq | -0.4218 | 0.0002 | |
| SRP219564 | NDST2 | 8509 | RNAseq | -1.1438 | 0.0027 | |
| TCGA | NDST2 | 8509 | RNAseq | -0.0855 | 0.1038 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NDST2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NDST2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDST2 | 8509 | 3 | 4 | 23 | |
| GSE20123 | NDST2 | 8509 | 3 | 3 | 24 | |
| GSE43470 | NDST2 | 8509 | 1 | 8 | 34 | |
| GSE46452 | NDST2 | 8509 | 0 | 11 | 48 | |
| GSE47630 | NDST2 | 8509 | 2 | 14 | 24 | |
| GSE54993 | NDST2 | 8509 | 7 | 0 | 63 | |
| GSE54994 | NDST2 | 8509 | 2 | 10 | 41 | |
| GSE60625 | NDST2 | 8509 | 0 | 0 | 11 | |
| GSE74703 | NDST2 | 8509 | 1 | 5 | 30 | |
| GSE74704 | NDST2 | 8509 | 1 | 1 | 18 | |
| TCGA | NDST2 | 8509 | 10 | 23 | 63 |
Total number of gains: 30; Total number of losses: 79; Total Number of normals: 379.
Somatic mutations of NDST2:
Generating mutation plots.
Highly correlated genes for NDST2:
Showing top 20/1169 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDST2 | FBXO10 | 0.787942 | 3 | 0 | 3 |
| NDST2 | ZNF570 | 0.767622 | 3 | 0 | 3 |
| NDST2 | ZNF829 | 0.753846 | 3 | 0 | 3 |
| NDST2 | MMEL1 | 0.739573 | 3 | 0 | 3 |
| NDST2 | EPC1 | 0.738446 | 3 | 0 | 3 |
| NDST2 | AKAP9 | 0.724148 | 3 | 0 | 3 |
| NDST2 | TIFA | 0.720696 | 5 | 0 | 4 |
| NDST2 | CGNL1 | 0.71636 | 4 | 0 | 4 |
| NDST2 | JMJD1C | 0.713326 | 3 | 0 | 3 |
| NDST2 | NOA1 | 0.705383 | 3 | 0 | 3 |
| NDST2 | MUC6 | 0.704348 | 3 | 0 | 3 |
| NDST2 | CANT1 | 0.703945 | 3 | 0 | 3 |
| NDST2 | RNF183 | 0.702967 | 3 | 0 | 3 |
| NDST2 | MBNL3 | 0.700711 | 4 | 0 | 3 |
| NDST2 | SLC44A3 | 0.699972 | 5 | 0 | 4 |
| NDST2 | ARSG | 0.698007 | 4 | 0 | 4 |
| NDST2 | IER3IP1 | 0.696074 | 3 | 0 | 3 |
| NDST2 | MYCN | 0.695881 | 4 | 0 | 4 |
| NDST2 | ULK3 | 0.69521 | 5 | 0 | 4 |
| NDST2 | KCTD18 | 0.691635 | 3 | 0 | 3 |
For details and further investigation, click here
