CCT3

 

Full name: chaperonin containing TCP1 subunit 3 Alias Symbol: Cctg
Type: protein-coding gene Cytoband: 1q22
Entrez ID: 7203 HGNC ID: HGNC:1616 Ensembl Gene: ENSG00000163468 OMIM ID: 600114
Drug and gene relationship at DGIdb

 

Expression of CCT3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCT3 7203 200910_at 0.8453 0.0317
GSE20347 CCT3 7203 200910_at 0.6451 0.0000
GSE23400 CCT3 7203 200910_at 0.8564 0.0000
GSE26886 CCT3 7203 200910_at 0.4681 0.0107
GSE29001 CCT3 7203 200910_at 0.5691 0.0475
GSE38129 CCT3 7203 200910_at 0.8430 0.0000
GSE45670 CCT3 7203 200910_at 0.5843 0.0004
GSE53622 CCT3 7203 41139 0.6076 0.0000
GSE53624 CCT3 7203 41139 0.8273 0.0000
GSE63941 CCT3 7203 200910_at 0.1983 0.5500
GSE77861 CCT3 7203 200910_at 0.6837 0.0006
GSE97050 CCT3 7203 A_23_P160631 0.4888 0.1887
SRP007169 CCT3 7203 RNAseq 1.2239 0.0006
SRP008496 CCT3 7203 RNAseq 1.3512 0.0001
SRP064894 CCT3 7203 RNAseq 0.6625 0.0003
SRP133303 CCT3 7203 RNAseq 0.7447 0.0000
SRP159526 CCT3 7203 RNAseq 0.9675 0.0000
SRP193095 CCT3 7203 RNAseq 0.5489 0.0004
SRP219564 CCT3 7203 RNAseq 0.5207 0.1786
TCGA CCT3 7203 RNAseq 0.2082 0.0000

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by CCT3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CCT3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCT3 7203 13 0 17
GSE20123 CCT3 7203 12 0 18
GSE43470 CCT3 7203 7 2 34
GSE46452 CCT3 7203 2 1 56
GSE47630 CCT3 7203 14 0 26
GSE54993 CCT3 7203 0 5 65
GSE54994 CCT3 7203 16 0 37
GSE60625 CCT3 7203 0 0 11
GSE74703 CCT3 7203 7 2 27
GSE74704 CCT3 7203 6 0 14
TCGA CCT3 7203 38 2 56

Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.  

 

Somatic mutations of CCT3:

 

Generating mutation plots.

 

Highly correlated genes for CCT3:

 

Showing top 20/1882 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCT3CKS1B0.78147712012
CCT3RUVBL10.77119512011
CCT3DHX90.76514410010
CCT3SNAP470.764191303
CCT3PFDN20.76297312010
CCT3UBE2C0.75562810010
CCT3TNFAIP8L10.754484303
CCT3AHSA10.74476411010
CCT3RFC40.74204111011
CCT3RANBP10.73766211010
CCT3DEPDC1B0.732207606
CCT3HOXC90.730278404
CCT3NUDT10.72994111011
CCT3PRKDC0.72867212011
CCT3MCM60.7278351009
CCT3CCT50.72719707
CCT3XPO50.726477707
CCT3ECT20.72473211010
CCT3GNPNAT10.724197505
CCT3KPNA20.724119808

For details and further investigation, click here