ACOT13

 

Full name: acyl-CoA thioesterase 13 Alias Symbol: HT012
Type: protein-coding gene Cytoband: 6p22.3
Entrez ID: 55856 HGNC ID: HGNC:20999 Ensembl Gene: ENSG00000112304 OMIM ID: 615652
Drug and gene relationship at DGIdb

 

Expression of ACOT13:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ACOT13 55856 204565_at 0.6890 0.2213
GSE20347 ACOT13 55856 204565_at 1.1205 0.0001
GSE23400 ACOT13 55856 204565_at 0.8947 0.0000
GSE26886 ACOT13 55856 204565_at 1.3857 0.0006
GSE29001 ACOT13 55856 204565_at 0.5097 0.0610
GSE38129 ACOT13 55856 204565_at 0.9677 0.0000
GSE45670 ACOT13 55856 204565_at 0.8439 0.0011
GSE63941 ACOT13 55856 204565_at 0.1150 0.8647
GSE77861 ACOT13 55856 204565_at 0.7328 0.2111
GSE97050 ACOT13 55856 A_23_P31116 0.1159 0.6864
SRP007169 ACOT13 55856 RNAseq 0.6859 0.1037
SRP008496 ACOT13 55856 RNAseq 0.4548 0.0921
SRP064894 ACOT13 55856 RNAseq 0.8621 0.0021
SRP133303 ACOT13 55856 RNAseq 0.1478 0.4415
SRP159526 ACOT13 55856 RNAseq 0.7292 0.0121
SRP193095 ACOT13 55856 RNAseq 0.0254 0.8292
SRP219564 ACOT13 55856 RNAseq 0.0014 0.9969
TCGA ACOT13 55856 RNAseq 0.0362 0.6481

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by ACOT13 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of ACOT13:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ACOT13 55856 4 2 24
GSE20123 ACOT13 55856 4 2 24
GSE43470 ACOT13 55856 5 0 38
GSE46452 ACOT13 55856 1 9 49
GSE47630 ACOT13 55856 8 5 27
GSE54993 ACOT13 55856 1 1 68
GSE54994 ACOT13 55856 10 4 39
GSE60625 ACOT13 55856 0 1 10
GSE74703 ACOT13 55856 5 0 31
GSE74704 ACOT13 55856 1 1 18
TCGA ACOT13 55856 17 20 59

Total number of gains: 56; Total number of losses: 45; Total Number of normals: 387.  

 

Somatic mutations of ACOT13:

 

Generating mutation plots.

 

Highly correlated genes for ACOT13:

 

Showing top 20/883 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ACOT13NDUFB90.741007303
ACOT13MPLKIP0.729075404
ACOT13GMNN0.703777807
ACOT13TDP20.70234908
ACOT13ATP6V1C10.695362707
ACOT13HAT10.681557707
ACOT13KIAA1614-AS10.677844303
ACOT13B3GNT90.677508404
ACOT13LRP120.676014908
ACOT13MED100.672234303
ACOT13XPO50.664741404
ACOT13NCBP10.664376505
ACOT13EXOSC30.662725303
ACOT13ODC10.662707707
ACOT13L3HYPDH0.661434403
ACOT13NUDT50.660308303
ACOT13MRPS280.656796606
ACOT13CMC20.656113808
ACOT13TXNRD10.65435706
ACOT13COA60.652461404

For details and further investigation, click here