| Full name: transmembrane protein 141 | Alias Symbol: MGC14141 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 85014 | HGNC ID: HGNC:28211 | Ensembl Gene: ENSG00000244187 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM141:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM141 | 85014 | 225568_at | -0.3700 | 0.2358 | |
| GSE26886 | TMEM141 | 85014 | 225568_at | -0.2867 | 0.0531 | |
| GSE45670 | TMEM141 | 85014 | 225568_at | -0.1905 | 0.0836 | |
| GSE53622 | TMEM141 | 85014 | 79385 | -0.4421 | 0.0000 | |
| GSE53624 | TMEM141 | 85014 | 79385 | -0.3623 | 0.0000 | |
| GSE63941 | TMEM141 | 85014 | 225568_at | 0.4574 | 0.1641 | |
| GSE77861 | TMEM141 | 85014 | 225568_at | -0.4164 | 0.0269 | |
| GSE97050 | TMEM141 | 85014 | A_23_P94591 | -0.0134 | 0.9737 | |
| SRP007169 | TMEM141 | 85014 | RNAseq | -1.4601 | 0.0021 | |
| SRP008496 | TMEM141 | 85014 | RNAseq | -1.4311 | 0.0000 | |
| SRP064894 | TMEM141 | 85014 | RNAseq | -0.2647 | 0.4670 | |
| SRP133303 | TMEM141 | 85014 | RNAseq | -0.6074 | 0.0065 | |
| SRP159526 | TMEM141 | 85014 | RNAseq | -0.8742 | 0.0000 | |
| SRP193095 | TMEM141 | 85014 | RNAseq | -1.2837 | 0.0000 | |
| SRP219564 | TMEM141 | 85014 | RNAseq | -0.2393 | 0.6002 | |
| TCGA | TMEM141 | 85014 | RNAseq | -0.0908 | 0.2554 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by TMEM141 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM141:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM141 | 85014 | 5 | 7 | 18 | |
| GSE20123 | TMEM141 | 85014 | 5 | 7 | 18 | |
| GSE43470 | TMEM141 | 85014 | 3 | 7 | 33 | |
| GSE46452 | TMEM141 | 85014 | 6 | 13 | 40 | |
| GSE47630 | TMEM141 | 85014 | 6 | 15 | 19 | |
| GSE54993 | TMEM141 | 85014 | 3 | 3 | 64 | |
| GSE54994 | TMEM141 | 85014 | 12 | 8 | 33 | |
| GSE60625 | TMEM141 | 85014 | 0 | 0 | 11 | |
| GSE74703 | TMEM141 | 85014 | 3 | 5 | 28 | |
| GSE74704 | TMEM141 | 85014 | 3 | 5 | 12 | |
| TCGA | TMEM141 | 85014 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of TMEM141:
Generating mutation plots.
Highly correlated genes for TMEM141:
Showing top 20/853 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM141 | NDUFS7 | 0.778526 | 4 | 0 | 4 |
| TMEM141 | TPRN | 0.737574 | 5 | 0 | 5 |
| TMEM141 | GRHL1 | 0.736333 | 3 | 0 | 3 |
| TMEM141 | MYADML2 | 0.728298 | 3 | 0 | 3 |
| TMEM141 | CRB3 | 0.727624 | 4 | 0 | 3 |
| TMEM141 | CST11 | 0.719959 | 3 | 0 | 3 |
| TMEM141 | TSSK2 | 0.709723 | 3 | 0 | 3 |
| TMEM141 | RASSF5 | 0.705074 | 4 | 0 | 4 |
| TMEM141 | RREB1 | 0.701546 | 4 | 0 | 4 |
| TMEM141 | PANK1 | 0.697411 | 3 | 0 | 3 |
| TMEM141 | SLC44A2 | 0.696952 | 5 | 0 | 4 |
| TMEM141 | FLYWCH2 | 0.696085 | 3 | 0 | 3 |
| TMEM141 | RETSAT | 0.690199 | 4 | 0 | 4 |
| TMEM141 | RABGAP1L | 0.687561 | 4 | 0 | 4 |
| TMEM141 | GPR37L1 | 0.684246 | 3 | 0 | 3 |
| TMEM141 | MFSD5 | 0.684137 | 7 | 0 | 5 |
| TMEM141 | RASAL1 | 0.683527 | 4 | 0 | 3 |
| TMEM141 | TAX1BP3 | 0.683138 | 3 | 0 | 3 |
| TMEM141 | ELOVL1 | 0.682774 | 3 | 0 | 3 |
| TMEM141 | ATG7 | 0.681925 | 3 | 0 | 3 |
For details and further investigation, click here
