| Full name: methyltransferase like 7A | Alias Symbol: DKFZP586A0522 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 25840 | HGNC ID: HGNC:24550 | Ensembl Gene: ENSG00000185432 | OMIM ID: 618338 |
| Drug and gene relationship at DGIdb | |||
Expression of METTL7A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | METTL7A | 25840 | 207761_s_at | -1.5917 | 0.0392 | |
| GSE20347 | METTL7A | 25840 | 207761_s_at | -1.4741 | 0.0001 | |
| GSE23400 | METTL7A | 25840 | 207761_s_at | -1.3178 | 0.0000 | |
| GSE26886 | METTL7A | 25840 | 207761_s_at | -1.5867 | 0.0402 | |
| GSE29001 | METTL7A | 25840 | 207761_s_at | -1.4187 | 0.0021 | |
| GSE38129 | METTL7A | 25840 | 207761_s_at | -1.7401 | 0.0000 | |
| GSE45670 | METTL7A | 25840 | 207761_s_at | -1.6653 | 0.0011 | |
| GSE53622 | METTL7A | 25840 | 14654 | -2.0191 | 0.0000 | |
| GSE53624 | METTL7A | 25840 | 14654 | -2.0264 | 0.0000 | |
| GSE63941 | METTL7A | 25840 | 207761_s_at | -1.4585 | 0.4628 | |
| GSE77861 | METTL7A | 25840 | 207761_s_at | -1.8078 | 0.0445 | |
| GSE97050 | METTL7A | 25840 | A_23_P415021 | -0.8685 | 0.0897 | |
| SRP007169 | METTL7A | 25840 | RNAseq | -1.1611 | 0.0494 | |
| SRP008496 | METTL7A | 25840 | RNAseq | -1.0143 | 0.0102 | |
| SRP064894 | METTL7A | 25840 | RNAseq | -0.5363 | 0.1725 | |
| SRP133303 | METTL7A | 25840 | RNAseq | -0.7898 | 0.0272 | |
| SRP159526 | METTL7A | 25840 | RNAseq | -0.2101 | 0.7516 | |
| SRP193095 | METTL7A | 25840 | RNAseq | -1.1611 | 0.0001 | |
| SRP219564 | METTL7A | 25840 | RNAseq | -0.4146 | 0.4289 | |
| TCGA | METTL7A | 25840 | RNAseq | -0.9238 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by METTL7A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of METTL7A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METTL7A | 25840 | 8 | 1 | 21 | |
| GSE20123 | METTL7A | 25840 | 8 | 1 | 21 | |
| GSE43470 | METTL7A | 25840 | 4 | 0 | 39 | |
| GSE46452 | METTL7A | 25840 | 8 | 1 | 50 | |
| GSE47630 | METTL7A | 25840 | 11 | 2 | 27 | |
| GSE54993 | METTL7A | 25840 | 0 | 5 | 65 | |
| GSE54994 | METTL7A | 25840 | 3 | 2 | 48 | |
| GSE60625 | METTL7A | 25840 | 0 | 0 | 11 | |
| GSE74703 | METTL7A | 25840 | 4 | 0 | 32 | |
| GSE74704 | METTL7A | 25840 | 5 | 1 | 14 | |
| TCGA | METTL7A | 25840 | 14 | 11 | 71 |
Total number of gains: 65; Total number of losses: 24; Total Number of normals: 399.
Somatic mutations of METTL7A:
Generating mutation plots.
Highly correlated genes for METTL7A:
Showing top 20/1656 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METTL7A | CLEC3B | 0.847063 | 3 | 0 | 3 |
| METTL7A | CYP21A2 | 0.81783 | 3 | 0 | 3 |
| METTL7A | ANGPTL1 | 0.802068 | 5 | 0 | 5 |
| METTL7A | GFRA1 | 0.793211 | 5 | 0 | 5 |
| METTL7A | LRRK2 | 0.793142 | 7 | 0 | 7 |
| METTL7A | MAMDC2 | 0.789645 | 5 | 0 | 5 |
| METTL7A | RAB9B | 0.785601 | 5 | 0 | 5 |
| METTL7A | KDM5D | 0.783083 | 3 | 0 | 3 |
| METTL7A | PLCXD3 | 0.77601 | 4 | 0 | 4 |
| METTL7A | NR2F1 | 0.773768 | 3 | 0 | 3 |
| METTL7A | NFIX | 0.765431 | 7 | 0 | 7 |
| METTL7A | RGS7BP | 0.764326 | 5 | 0 | 5 |
| METTL7A | ASPA | 0.762964 | 9 | 0 | 9 |
| METTL7A | CTTNBP2 | 0.761665 | 6 | 0 | 6 |
| METTL7A | OGN | 0.757907 | 7 | 0 | 7 |
| METTL7A | SVIP | 0.75691 | 7 | 0 | 7 |
| METTL7A | GBP6 | 0.755355 | 3 | 0 | 3 |
| METTL7A | CFD | 0.748165 | 9 | 0 | 8 |
| METTL7A | NEXN | 0.747232 | 4 | 0 | 4 |
| METTL7A | PLAC9 | 0.746696 | 6 | 0 | 5 |
For details and further investigation, click here
