| Full name: NGG1 interacting factor 3 like 1 | Alias Symbol: CALS-7|MDS015 | ||
| Type: protein-coding gene | Cytoband: 2q33.1 | ||
| Entrez ID: 60491 | HGNC ID: HGNC:13390 | Ensembl Gene: ENSG00000196290 | OMIM ID: 605778 |
| Drug and gene relationship at DGIdb | |||
Expression of NIF3L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NIF3L1 | 60491 | 218133_s_at | 0.4420 | 0.1772 | |
| GSE20347 | NIF3L1 | 60491 | 218133_s_at | 0.5994 | 0.0020 | |
| GSE23400 | NIF3L1 | 60491 | 218133_s_at | 0.5615 | 0.0000 | |
| GSE26886 | NIF3L1 | 60491 | 218133_s_at | -0.0883 | 0.7147 | |
| GSE29001 | NIF3L1 | 60491 | 218133_s_at | 0.4787 | 0.0551 | |
| GSE38129 | NIF3L1 | 60491 | 218133_s_at | 0.7668 | 0.0000 | |
| GSE45670 | NIF3L1 | 60491 | 218133_s_at | 0.3518 | 0.0394 | |
| GSE53622 | NIF3L1 | 60491 | 85362 | 0.7990 | 0.0000 | |
| GSE53624 | NIF3L1 | 60491 | 131023 | 0.5534 | 0.0000 | |
| GSE63941 | NIF3L1 | 60491 | 218133_s_at | 0.7397 | 0.0499 | |
| GSE77861 | NIF3L1 | 60491 | 218133_s_at | 0.2748 | 0.2309 | |
| GSE97050 | NIF3L1 | 60491 | A_33_P3255766 | 0.5133 | 0.1449 | |
| SRP007169 | NIF3L1 | 60491 | RNAseq | 0.0801 | 0.8603 | |
| SRP008496 | NIF3L1 | 60491 | RNAseq | 0.3221 | 0.1856 | |
| SRP064894 | NIF3L1 | 60491 | RNAseq | 0.1631 | 0.3332 | |
| SRP133303 | NIF3L1 | 60491 | RNAseq | 0.2852 | 0.0897 | |
| SRP159526 | NIF3L1 | 60491 | RNAseq | 0.3355 | 0.1406 | |
| SRP193095 | NIF3L1 | 60491 | RNAseq | 0.0647 | 0.5656 | |
| SRP219564 | NIF3L1 | 60491 | RNAseq | 0.1191 | 0.6566 | |
| TCGA | NIF3L1 | 60491 | RNAseq | 0.1275 | 0.0248 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NIF3L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NIF3L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NIF3L1 | 60491 | 6 | 4 | 20 | |
| GSE20123 | NIF3L1 | 60491 | 6 | 4 | 20 | |
| GSE43470 | NIF3L1 | 60491 | 2 | 1 | 40 | |
| GSE46452 | NIF3L1 | 60491 | 1 | 4 | 54 | |
| GSE47630 | NIF3L1 | 60491 | 4 | 5 | 31 | |
| GSE54993 | NIF3L1 | 60491 | 0 | 3 | 67 | |
| GSE54994 | NIF3L1 | 60491 | 10 | 8 | 35 | |
| GSE60625 | NIF3L1 | 60491 | 0 | 3 | 8 | |
| GSE74703 | NIF3L1 | 60491 | 2 | 1 | 33 | |
| GSE74704 | NIF3L1 | 60491 | 3 | 2 | 15 | |
| TCGA | NIF3L1 | 60491 | 22 | 11 | 63 |
Total number of gains: 56; Total number of losses: 46; Total Number of normals: 386.
Somatic mutations of NIF3L1:
Generating mutation plots.
Highly correlated genes for NIF3L1:
Showing top 20/1394 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NIF3L1 | MARS2 | 0.763711 | 4 | 0 | 4 |
| NIF3L1 | TRUB1 | 0.761775 | 4 | 0 | 3 |
| NIF3L1 | GTF2H3 | 0.761554 | 3 | 0 | 3 |
| NIF3L1 | ZBTB9 | 0.741715 | 4 | 0 | 4 |
| NIF3L1 | SWAP70 | 0.722924 | 3 | 0 | 3 |
| NIF3L1 | GNG10 | 0.720214 | 3 | 0 | 3 |
| NIF3L1 | MMS22L | 0.717425 | 3 | 0 | 3 |
| NIF3L1 | MASTL | 0.713684 | 6 | 0 | 5 |
| NIF3L1 | POC5 | 0.713201 | 4 | 0 | 3 |
| NIF3L1 | ZDHHC4 | 0.709992 | 5 | 0 | 4 |
| NIF3L1 | NUP35 | 0.706185 | 6 | 0 | 6 |
| NIF3L1 | CFDP1 | 0.705474 | 3 | 0 | 3 |
| NIF3L1 | UTP23 | 0.702213 | 3 | 0 | 3 |
| NIF3L1 | BCCIP | 0.701313 | 7 | 0 | 7 |
| NIF3L1 | WDR12 | 0.700796 | 13 | 0 | 11 |
| NIF3L1 | TMEM237 | 0.699278 | 6 | 0 | 5 |
| NIF3L1 | MCM6 | 0.694411 | 12 | 0 | 12 |
| NIF3L1 | GTF3C3 | 0.693959 | 13 | 0 | 12 |
| NIF3L1 | SNX30 | 0.693508 | 4 | 0 | 3 |
| NIF3L1 | OSBPL6 | 0.692846 | 3 | 0 | 3 |
For details and further investigation, click here
