GTF3C3

 

Full name: general transcription factor IIIC subunit 3 Alias Symbol: TFiiiC2-102|TFIIIC102
Type: protein-coding gene Cytoband: 2q33.1
Entrez ID: 9330 HGNC ID: HGNC:4666 Ensembl Gene: ENSG00000119041 OMIM ID: 604888
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of GTF3C3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GTF3C3 9330 218343_s_at 0.4026 0.2375
GSE20347 GTF3C3 9330 218343_s_at 0.6004 0.0087
GSE23400 GTF3C3 9330 218343_s_at 0.8036 0.0000
GSE26886 GTF3C3 9330 218343_s_at 0.7229 0.0163
GSE29001 GTF3C3 9330 218343_s_at 0.4345 0.1994
GSE38129 GTF3C3 9330 218343_s_at 0.9763 0.0000
GSE45670 GTF3C3 9330 218343_s_at 0.2704 0.1439
GSE53622 GTF3C3 9330 59084 0.5766 0.0000
GSE53624 GTF3C3 9330 59084 0.3884 0.0000
GSE63941 GTF3C3 9330 218343_s_at 0.8247 0.0508
GSE77861 GTF3C3 9330 218343_s_at 0.6277 0.0089
GSE97050 GTF3C3 9330 A_23_P429535 0.3362 0.1927
SRP007169 GTF3C3 9330 RNAseq 0.5237 0.1128
SRP008496 GTF3C3 9330 RNAseq 0.8240 0.0000
SRP064894 GTF3C3 9330 RNAseq 0.1698 0.3425
SRP133303 GTF3C3 9330 RNAseq 0.4502 0.0000
SRP159526 GTF3C3 9330 RNAseq 0.3633 0.0403
SRP193095 GTF3C3 9330 RNAseq 0.1554 0.1011
SRP219564 GTF3C3 9330 RNAseq -0.0244 0.9245
TCGA GTF3C3 9330 RNAseq 0.1361 0.0081

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by GTF3C3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of GTF3C3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GTF3C3 9330 10 2 18
GSE20123 GTF3C3 9330 10 2 18
GSE43470 GTF3C3 9330 3 1 39
GSE46452 GTF3C3 9330 1 4 54
GSE47630 GTF3C3 9330 4 5 31
GSE54993 GTF3C3 9330 0 4 66
GSE54994 GTF3C3 9330 11 7 35
GSE60625 GTF3C3 9330 0 3 8
GSE74703 GTF3C3 9330 2 1 33
GSE74704 GTF3C3 9330 5 2 13
TCGA GTF3C3 9330 22 9 65

Total number of gains: 68; Total number of losses: 40; Total Number of normals: 380.  

 

Somatic mutations of GTF3C3:

 

Generating mutation plots.

 

Highly correlated genes for GTF3C3:

 

Showing top 20/1477 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GTF3C3TMTC30.755066303
GTF3C3VMA210.725693504
GTF3C3RNASET20.718479303
GTF3C3RAC20.716535303
GTF3C3NFKB10.714593303
GTF3C3FCER1G0.70733303
GTF3C3PLEKHA80.705113303
GTF3C3YWHAG0.698717303
GTF3C3PYCR20.695958303
GTF3C3NIF3L10.69395913012
GTF3C3RNF1660.69238303
GTF3C3XPNPEP30.692256403
GTF3C3HSPD10.69077612010
GTF3C3PARVB0.690588303
GTF3C3ELF20.688836303
GTF3C3POLDIP20.68635404
GTF3C3SMCR80.679811605
GTF3C3DCUN1D20.679281303
GTF3C3PEX20.67824404
GTF3C3WDR750.677619706

For details and further investigation, click here