| Full name: POC5 centriolar protein | Alias Symbol: FLJ35779|MGC120442|MGC120443|MGC120444|hPOC5 | ||
| Type: protein-coding gene | Cytoband: 5q13.3 | ||
| Entrez ID: 134359 | HGNC ID: HGNC:26658 | Ensembl Gene: ENSG00000152359 | OMIM ID: 617880 |
| Drug and gene relationship at DGIdb | |||
Expression of POC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POC5 | 134359 | 227267_at | 0.3747 | 0.2711 | |
| GSE26886 | POC5 | 134359 | 227267_at | 1.3951 | 0.0000 | |
| GSE45670 | POC5 | 134359 | 227267_at | 0.3095 | 0.0804 | |
| GSE53622 | POC5 | 134359 | 16290 | 0.6611 | 0.0000 | |
| GSE53624 | POC5 | 134359 | 16290 | 0.8384 | 0.0000 | |
| GSE63941 | POC5 | 134359 | 227267_at | 0.9670 | 0.0237 | |
| GSE77861 | POC5 | 134359 | 227267_at | 0.2485 | 0.2079 | |
| GSE97050 | POC5 | 134359 | A_23_P413803 | 0.3043 | 0.2778 | |
| SRP007169 | POC5 | 134359 | RNAseq | 0.4131 | 0.4162 | |
| SRP008496 | POC5 | 134359 | RNAseq | 0.2746 | 0.4851 | |
| SRP064894 | POC5 | 134359 | RNAseq | 0.6013 | 0.0010 | |
| SRP133303 | POC5 | 134359 | RNAseq | 0.5354 | 0.0005 | |
| SRP159526 | POC5 | 134359 | RNAseq | 0.4412 | 0.1320 | |
| SRP193095 | POC5 | 134359 | RNAseq | 0.1882 | 0.0481 | |
| SRP219564 | POC5 | 134359 | RNAseq | 0.4848 | 0.0818 | |
| TCGA | POC5 | 134359 | RNAseq | 0.2828 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by POC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POC5 | 134359 | 1 | 13 | 16 | |
| GSE20123 | POC5 | 134359 | 1 | 13 | 16 | |
| GSE43470 | POC5 | 134359 | 1 | 13 | 29 | |
| GSE46452 | POC5 | 134359 | 0 | 28 | 31 | |
| GSE47630 | POC5 | 134359 | 1 | 19 | 20 | |
| GSE54993 | POC5 | 134359 | 8 | 1 | 61 | |
| GSE54994 | POC5 | 134359 | 1 | 19 | 33 | |
| GSE60625 | POC5 | 134359 | 0 | 0 | 11 | |
| GSE74703 | POC5 | 134359 | 1 | 9 | 26 | |
| GSE74704 | POC5 | 134359 | 1 | 6 | 13 | |
| TCGA | POC5 | 134359 | 4 | 50 | 42 |
Total number of gains: 19; Total number of losses: 171; Total Number of normals: 298.
Somatic mutations of POC5:
Generating mutation plots.
Highly correlated genes for POC5:
Showing top 20/1314 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POC5 | GDE1 | 0.759289 | 3 | 0 | 3 |
| POC5 | ARTN | 0.756155 | 3 | 0 | 3 |
| POC5 | C19orf54 | 0.745483 | 3 | 0 | 3 |
| POC5 | INPP5B | 0.742397 | 3 | 0 | 3 |
| POC5 | SNTB2 | 0.736555 | 4 | 0 | 3 |
| POC5 | RNASEH2C | 0.733806 | 3 | 0 | 3 |
| POC5 | HERPUD2 | 0.733393 | 3 | 0 | 3 |
| POC5 | UHRF1BP1 | 0.732041 | 4 | 0 | 4 |
| POC5 | GNPDA1 | 0.729595 | 6 | 0 | 6 |
| POC5 | SCNM1 | 0.729428 | 3 | 0 | 3 |
| POC5 | ZC3H12C | 0.728337 | 4 | 0 | 4 |
| POC5 | PLEKHA3 | 0.725917 | 4 | 0 | 4 |
| POC5 | LRRC58 | 0.72577 | 3 | 0 | 3 |
| POC5 | PYCR2 | 0.722838 | 3 | 0 | 3 |
| POC5 | HEXA | 0.72142 | 4 | 0 | 4 |
| POC5 | MPG | 0.721156 | 4 | 0 | 4 |
| POC5 | PMS2 | 0.721152 | 3 | 0 | 3 |
| POC5 | HEXB | 0.719809 | 7 | 0 | 6 |
| POC5 | PSMA2 | 0.716843 | 3 | 0 | 3 |
| POC5 | NIF3L1 | 0.713201 | 4 | 0 | 3 |
For details and further investigation, click here
