| Full name: nucleolar pre-rRNA processing protein NIP7 | Alias Symbol: CGI-37|FLJ10296|HSPC031|KD93 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 51388 | HGNC ID: HGNC:24328 | Ensembl Gene: ENSG00000132603 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NIP7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NIP7 | 51388 | 219031_s_at | 0.9414 | 0.1775 | |
| GSE20347 | NIP7 | 51388 | 219031_s_at | 0.3887 | 0.0503 | |
| GSE23400 | NIP7 | 51388 | 219031_s_at | 0.2730 | 0.0000 | |
| GSE26886 | NIP7 | 51388 | 219031_s_at | -0.9600 | 0.0005 | |
| GSE29001 | NIP7 | 51388 | 219031_s_at | 0.3235 | 0.4903 | |
| GSE38129 | NIP7 | 51388 | 219031_s_at | 0.7216 | 0.0068 | |
| GSE45670 | NIP7 | 51388 | 219031_s_at | 0.4327 | 0.0118 | |
| GSE53622 | NIP7 | 51388 | 171082 | 0.5729 | 0.0000 | |
| GSE53624 | NIP7 | 51388 | 171082 | 0.5647 | 0.0000 | |
| GSE63941 | NIP7 | 51388 | 219031_s_at | 0.4957 | 0.3114 | |
| GSE77861 | NIP7 | 51388 | 223397_s_at | 0.3625 | 0.2722 | |
| GSE97050 | NIP7 | 51388 | A_33_P3283906 | 0.5833 | 0.1512 | |
| SRP007169 | NIP7 | 51388 | RNAseq | 0.2700 | 0.4819 | |
| SRP008496 | NIP7 | 51388 | RNAseq | 0.3465 | 0.2322 | |
| SRP064894 | NIP7 | 51388 | RNAseq | 0.0253 | 0.8896 | |
| SRP133303 | NIP7 | 51388 | RNAseq | 0.7395 | 0.0000 | |
| SRP159526 | NIP7 | 51388 | RNAseq | 0.3877 | 0.1312 | |
| SRP193095 | NIP7 | 51388 | RNAseq | 0.2969 | 0.0504 | |
| SRP219564 | NIP7 | 51388 | RNAseq | 0.0350 | 0.9369 | |
| TCGA | NIP7 | 51388 | RNAseq | 0.3488 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NIP7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NIP7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NIP7 | 51388 | 8 | 1 | 21 | |
| GSE20123 | NIP7 | 51388 | 8 | 1 | 21 | |
| GSE43470 | NIP7 | 51388 | 2 | 7 | 34 | |
| GSE46452 | NIP7 | 51388 | 38 | 1 | 20 | |
| GSE47630 | NIP7 | 51388 | 11 | 8 | 21 | |
| GSE54993 | NIP7 | 51388 | 2 | 4 | 64 | |
| GSE54994 | NIP7 | 51388 | 8 | 10 | 35 | |
| GSE60625 | NIP7 | 51388 | 4 | 0 | 7 | |
| GSE74703 | NIP7 | 51388 | 2 | 4 | 30 | |
| GSE74704 | NIP7 | 51388 | 4 | 0 | 16 | |
| TCGA | NIP7 | 51388 | 29 | 12 | 55 |
Total number of gains: 116; Total number of losses: 48; Total Number of normals: 324.
Somatic mutations of NIP7:
Generating mutation plots.
Highly correlated genes for NIP7:
Showing top 20/786 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NIP7 | ZGPAT | 0.727672 | 3 | 0 | 3 |
| NIP7 | NIPBL | 0.715107 | 3 | 0 | 3 |
| NIP7 | TUBGCP4 | 0.713874 | 4 | 0 | 4 |
| NIP7 | LRP8 | 0.695905 | 6 | 0 | 5 |
| NIP7 | IPMK | 0.687579 | 3 | 0 | 3 |
| NIP7 | FAM118B | 0.682748 | 3 | 0 | 3 |
| NIP7 | SLC7A6OS | 0.679832 | 4 | 0 | 4 |
| NIP7 | INTS12 | 0.678301 | 3 | 0 | 3 |
| NIP7 | CCT6A | 0.670816 | 8 | 0 | 6 |
| NIP7 | EIF2S1 | 0.670684 | 9 | 0 | 7 |
| NIP7 | ABCE1 | 0.667939 | 11 | 0 | 11 |
| NIP7 | WDR53 | 0.667569 | 4 | 0 | 4 |
| NIP7 | TP53RK | 0.66522 | 4 | 0 | 4 |
| NIP7 | PDE8A | 0.664273 | 3 | 0 | 3 |
| NIP7 | NOP56 | 0.66146 | 3 | 0 | 3 |
| NIP7 | STAU1 | 0.658802 | 4 | 0 | 4 |
| NIP7 | CSE1L | 0.657921 | 10 | 0 | 9 |
| NIP7 | FAM89A | 0.656209 | 4 | 0 | 4 |
| NIP7 | ELP4 | 0.654498 | 5 | 0 | 4 |
| NIP7 | NUS1 | 0.648686 | 5 | 0 | 4 |
For details and further investigation, click here
