| Full name: elongator acetyltransferase complex subunit 4 | Alias Symbol: PAXNEB | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 26610 | HGNC ID: HGNC:1171 | Ensembl Gene: ENSG00000109911 | OMIM ID: 606985 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ELP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELP4 | 26610 | 203829_at | 0.0733 | 0.7308 | |
| GSE20347 | ELP4 | 26610 | 203829_at | -0.3361 | 0.0355 | |
| GSE23400 | ELP4 | 26610 | 203829_at | 0.0030 | 0.9514 | |
| GSE26886 | ELP4 | 26610 | 203829_at | -0.6733 | 0.0007 | |
| GSE29001 | ELP4 | 26610 | 203829_at | -0.1054 | 0.8101 | |
| GSE38129 | ELP4 | 26610 | 203829_at | -0.0383 | 0.8169 | |
| GSE45670 | ELP4 | 26610 | 203829_at | 0.0429 | 0.8314 | |
| GSE53622 | ELP4 | 26610 | 26594 | -0.0346 | 0.6813 | |
| GSE53624 | ELP4 | 26610 | 26594 | 0.0598 | 0.3256 | |
| GSE63941 | ELP4 | 26610 | 203829_at | 1.0484 | 0.0181 | |
| GSE77861 | ELP4 | 26610 | 203829_at | -0.0600 | 0.8134 | |
| GSE97050 | ELP4 | 26610 | A_23_P24623 | 0.0542 | 0.8485 | |
| SRP007169 | ELP4 | 26610 | RNAseq | -0.1453 | 0.7590 | |
| SRP008496 | ELP4 | 26610 | RNAseq | -0.1527 | 0.5668 | |
| SRP064894 | ELP4 | 26610 | RNAseq | -0.1432 | 0.2290 | |
| SRP133303 | ELP4 | 26610 | RNAseq | 0.2320 | 0.1538 | |
| SRP159526 | ELP4 | 26610 | RNAseq | -0.5697 | 0.0087 | |
| SRP193095 | ELP4 | 26610 | RNAseq | -0.3964 | 0.0000 | |
| SRP219564 | ELP4 | 26610 | RNAseq | -0.2061 | 0.4295 | |
| TCGA | ELP4 | 26610 | RNAseq | 0.1392 | 0.0304 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ELP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELP4 | 26610 | 1 | 9 | 20 | |
| GSE20123 | ELP4 | 26610 | 1 | 8 | 21 | |
| GSE43470 | ELP4 | 26610 | 2 | 5 | 36 | |
| GSE46452 | ELP4 | 26610 | 8 | 5 | 46 | |
| GSE47630 | ELP4 | 26610 | 3 | 10 | 27 | |
| GSE54993 | ELP4 | 26610 | 3 | 0 | 67 | |
| GSE54994 | ELP4 | 26610 | 4 | 10 | 39 | |
| GSE60625 | ELP4 | 26610 | 0 | 0 | 11 | |
| GSE74703 | ELP4 | 26610 | 2 | 3 | 31 | |
| GSE74704 | ELP4 | 26610 | 0 | 7 | 13 | |
| TCGA | ELP4 | 26610 | 12 | 24 | 60 |
Total number of gains: 36; Total number of losses: 81; Total Number of normals: 371.
Somatic mutations of ELP4:
Generating mutation plots.
Highly correlated genes for ELP4:
Showing top 20/459 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELP4 | ADCY7 | 0.778298 | 3 | 0 | 3 |
| ELP4 | IRAK2 | 0.758136 | 3 | 0 | 3 |
| ELP4 | CCT2 | 0.756231 | 3 | 0 | 3 |
| ELP4 | RIOK2 | 0.742105 | 4 | 0 | 4 |
| ELP4 | PLSCR1 | 0.73758 | 3 | 0 | 3 |
| ELP4 | SNX20 | 0.73545 | 3 | 0 | 3 |
| ELP4 | GFM2 | 0.731875 | 3 | 0 | 3 |
| ELP4 | UNC5B | 0.730212 | 3 | 0 | 3 |
| ELP4 | CASP3 | 0.723805 | 3 | 0 | 3 |
| ELP4 | MPHOSPH6 | 0.717806 | 3 | 0 | 3 |
| ELP4 | THAP2 | 0.716615 | 3 | 0 | 3 |
| ELP4 | CST6 | 0.713545 | 3 | 0 | 3 |
| ELP4 | RNF149 | 0.703803 | 4 | 0 | 4 |
| ELP4 | COPS2 | 0.702958 | 4 | 0 | 3 |
| ELP4 | CSNK2A2 | 0.696674 | 4 | 0 | 3 |
| ELP4 | SPIN4 | 0.692724 | 3 | 0 | 3 |
| ELP4 | ANKMY2 | 0.692551 | 3 | 0 | 3 |
| ELP4 | RRAGA | 0.689993 | 4 | 0 | 4 |
| ELP4 | TRAF7 | 0.685013 | 3 | 0 | 3 |
| ELP4 | UFC1 | 0.683633 | 4 | 0 | 4 |
For details and further investigation, click here
