| Full name: ankyrin repeat and sterile alpha motif domain containing 6 | Alias Symbol: FLJ36928|NPHP16 | ||
| Type: protein-coding gene | Cytoband: 9q22.33 | ||
| Entrez ID: 203286 | HGNC ID: HGNC:26724 | Ensembl Gene: ENSG00000165138 | OMIM ID: 615370 |
| Drug and gene relationship at DGIdb | |||
Expression of ANKS6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANKS6 | 203286 | 226586_at | 0.2193 | 0.5667 | |
| GSE26886 | ANKS6 | 203286 | 226586_at | 0.1496 | 0.3109 | |
| GSE45670 | ANKS6 | 203286 | 226586_at | -0.1479 | 0.2323 | |
| GSE53622 | ANKS6 | 203286 | 118446 | -0.3437 | 0.0007 | |
| GSE53624 | ANKS6 | 203286 | 118446 | -0.1498 | 0.0856 | |
| GSE63941 | ANKS6 | 203286 | 226586_at | 0.2878 | 0.5458 | |
| GSE77861 | ANKS6 | 203286 | 226586_at | 0.1011 | 0.5331 | |
| GSE97050 | ANKS6 | 203286 | A_23_P362183 | -0.1185 | 0.6358 | |
| SRP007169 | ANKS6 | 203286 | RNAseq | -0.8262 | 0.1725 | |
| SRP008496 | ANKS6 | 203286 | RNAseq | -0.4174 | 0.2718 | |
| SRP064894 | ANKS6 | 203286 | RNAseq | 0.0140 | 0.9362 | |
| SRP133303 | ANKS6 | 203286 | RNAseq | -0.6116 | 0.0000 | |
| SRP159526 | ANKS6 | 203286 | RNAseq | 0.0762 | 0.7188 | |
| SRP193095 | ANKS6 | 203286 | RNAseq | -0.1589 | 0.2963 | |
| SRP219564 | ANKS6 | 203286 | RNAseq | 0.1027 | 0.7341 | |
| TCGA | ANKS6 | 203286 | RNAseq | -0.2204 | 0.0033 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ANKS6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANKS6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANKS6 | 203286 | 5 | 9 | 16 | |
| GSE20123 | ANKS6 | 203286 | 5 | 8 | 17 | |
| GSE43470 | ANKS6 | 203286 | 6 | 3 | 34 | |
| GSE46452 | ANKS6 | 203286 | 6 | 13 | 40 | |
| GSE47630 | ANKS6 | 203286 | 1 | 17 | 22 | |
| GSE54993 | ANKS6 | 203286 | 3 | 3 | 64 | |
| GSE54994 | ANKS6 | 203286 | 8 | 11 | 34 | |
| GSE60625 | ANKS6 | 203286 | 0 | 0 | 11 | |
| GSE74703 | ANKS6 | 203286 | 5 | 3 | 28 | |
| GSE74704 | ANKS6 | 203286 | 3 | 5 | 12 | |
| TCGA | ANKS6 | 203286 | 27 | 22 | 47 |
Total number of gains: 69; Total number of losses: 94; Total Number of normals: 325.
Somatic mutations of ANKS6:
Generating mutation plots.
Highly correlated genes for ANKS6:
Showing top 20/126 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANKS6 | EIF2AK4 | 0.826217 | 3 | 0 | 3 |
| ANKS6 | PAK1 | 0.787613 | 3 | 0 | 3 |
| ANKS6 | RNF26 | 0.787533 | 3 | 0 | 3 |
| ANKS6 | AQR | 0.783994 | 3 | 0 | 3 |
| ANKS6 | SMAD3 | 0.782844 | 3 | 0 | 3 |
| ANKS6 | DUT | 0.778262 | 3 | 0 | 3 |
| ANKS6 | HMG20A | 0.776322 | 3 | 0 | 3 |
| ANKS6 | ACP1 | 0.774511 | 3 | 0 | 3 |
| ANKS6 | SPCS2 | 0.76539 | 3 | 0 | 3 |
| ANKS6 | SNRPA1 | 0.763994 | 3 | 0 | 3 |
| ANKS6 | ALG8 | 0.741914 | 3 | 0 | 3 |
| ANKS6 | MBTPS2 | 0.739371 | 3 | 0 | 3 |
| ANKS6 | SPAST | 0.727427 | 3 | 0 | 3 |
| ANKS6 | ZWILCH | 0.725514 | 3 | 0 | 3 |
| ANKS6 | TMEM60 | 0.724084 | 3 | 0 | 3 |
| ANKS6 | NUSAP1 | 0.723829 | 3 | 0 | 3 |
| ANKS6 | MASTL | 0.722616 | 3 | 0 | 3 |
| ANKS6 | PRC1 | 0.721984 | 3 | 0 | 3 |
| ANKS6 | SEC11A | 0.718701 | 3 | 0 | 3 |
| ANKS6 | UNC45A | 0.714407 | 3 | 0 | 3 |
For details and further investigation, click here
