| Full name: nuclear receptor subfamily 3 group C member 1 | Alias Symbol: GR | ||
| Type: protein-coding gene | Cytoband: 5q31.3 | ||
| Entrez ID: 2908 | HGNC ID: HGNC:7978 | Ensembl Gene: ENSG00000113580 | OMIM ID: 138040 |
| Drug and gene relationship at DGIdb | |||
Expression of NR3C1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NR3C1 | 2908 | 201865_x_at | -0.1341 | 0.8141 | |
| GSE20347 | NR3C1 | 2908 | 201865_x_at | -0.0163 | 0.9173 | |
| GSE23400 | NR3C1 | 2908 | 201865_x_at | 0.2345 | 0.0066 | |
| GSE26886 | NR3C1 | 2908 | 201865_x_at | 0.3699 | 0.1092 | |
| GSE29001 | NR3C1 | 2908 | 201865_x_at | 0.1980 | 0.2962 | |
| GSE38129 | NR3C1 | 2908 | 201865_x_at | -0.3161 | 0.0181 | |
| GSE45670 | NR3C1 | 2908 | 201865_x_at | -0.1345 | 0.5257 | |
| GSE53622 | NR3C1 | 2908 | 84500 | -0.2062 | 0.0061 | |
| GSE53624 | NR3C1 | 2908 | 84500 | -0.0203 | 0.7856 | |
| GSE63941 | NR3C1 | 2908 | 201865_x_at | -0.5175 | 0.3897 | |
| GSE77861 | NR3C1 | 2908 | 201865_x_at | 0.2423 | 0.7374 | |
| GSE97050 | NR3C1 | 2908 | A_33_P3767927 | -0.1976 | 0.4989 | |
| SRP007169 | NR3C1 | 2908 | RNAseq | 0.0263 | 0.9319 | |
| SRP008496 | NR3C1 | 2908 | RNAseq | 0.0511 | 0.7927 | |
| SRP064894 | NR3C1 | 2908 | RNAseq | -0.0501 | 0.7640 | |
| SRP133303 | NR3C1 | 2908 | RNAseq | 0.4020 | 0.0297 | |
| SRP159526 | NR3C1 | 2908 | RNAseq | -0.0891 | 0.8398 | |
| SRP193095 | NR3C1 | 2908 | RNAseq | -0.0425 | 0.6581 | |
| SRP219564 | NR3C1 | 2908 | RNAseq | 0.2528 | 0.4516 | |
| TCGA | NR3C1 | 2908 | RNAseq | 0.0098 | 0.8521 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NR3C1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NR3C1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NR3C1 | 2908 | 1 | 12 | 17 | |
| GSE20123 | NR3C1 | 2908 | 1 | 12 | 17 | |
| GSE43470 | NR3C1 | 2908 | 2 | 10 | 31 | |
| GSE46452 | NR3C1 | 2908 | 0 | 27 | 32 | |
| GSE47630 | NR3C1 | 2908 | 0 | 20 | 20 | |
| GSE54993 | NR3C1 | 2908 | 9 | 1 | 60 | |
| GSE54994 | NR3C1 | 2908 | 2 | 14 | 37 | |
| GSE60625 | NR3C1 | 2908 | 0 | 0 | 11 | |
| GSE74703 | NR3C1 | 2908 | 2 | 7 | 27 | |
| GSE74704 | NR3C1 | 2908 | 1 | 6 | 13 | |
| TCGA | NR3C1 | 2908 | 3 | 38 | 55 |
Total number of gains: 21; Total number of losses: 147; Total Number of normals: 320.
Somatic mutations of NR3C1:
Generating mutation plots.
Highly correlated genes for NR3C1:
Showing top 20/240 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NR3C1 | SGTB | 0.745679 | 4 | 0 | 4 |
| NR3C1 | DZIP1 | 0.741908 | 3 | 0 | 3 |
| NR3C1 | TYW3 | 0.730912 | 3 | 0 | 3 |
| NR3C1 | TCEA1 | 0.724848 | 3 | 0 | 3 |
| NR3C1 | CCNH | 0.706197 | 4 | 0 | 3 |
| NR3C1 | C5orf24 | 0.697596 | 4 | 0 | 3 |
| NR3C1 | IRS2 | 0.689539 | 3 | 0 | 3 |
| NR3C1 | CKMT2-AS1 | 0.689141 | 3 | 0 | 3 |
| NR3C1 | C11orf58 | 0.689058 | 4 | 0 | 3 |
| NR3C1 | POLK | 0.687698 | 4 | 0 | 3 |
| NR3C1 | FMR1 | 0.684012 | 3 | 0 | 3 |
| NR3C1 | NUAK1 | 0.683354 | 3 | 0 | 3 |
| NR3C1 | EIF3L | 0.681121 | 3 | 0 | 3 |
| NR3C1 | PTP4A2 | 0.680044 | 4 | 0 | 3 |
| NR3C1 | HIF1A | 0.677887 | 3 | 0 | 3 |
| NR3C1 | DNAJC18 | 0.669858 | 4 | 0 | 3 |
| NR3C1 | RAB8B | 0.668568 | 4 | 0 | 4 |
| NR3C1 | EIF3M | 0.66714 | 4 | 0 | 3 |
| NR3C1 | DOCK7 | 0.662921 | 4 | 0 | 3 |
| NR3C1 | SCAMP1 | 0.661851 | 4 | 0 | 3 |
For details and further investigation, click here
