| Full name: neurturin | Alias Symbol: NTN | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 4902 | HGNC ID: HGNC:8007 | Ensembl Gene: ENSG00000171119 | OMIM ID: 602018 |
| Drug and gene relationship at DGIdb | |||
Expression of NRTN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NRTN | 4902 | 210683_at | -0.4219 | 0.5786 | |
| GSE20347 | NRTN | 4902 | 210683_at | -0.0578 | 0.8527 | |
| GSE23400 | NRTN | 4902 | 210683_at | -0.0476 | 0.4629 | |
| GSE26886 | NRTN | 4902 | 210683_at | 0.2516 | 0.6833 | |
| GSE29001 | NRTN | 4902 | 210683_at | -0.1738 | 0.7901 | |
| GSE38129 | NRTN | 4902 | 210683_at | -0.3147 | 0.2268 | |
| GSE45670 | NRTN | 4902 | 210683_at | -0.1771 | 0.5614 | |
| GSE53622 | NRTN | 4902 | 17157 | 0.4390 | 0.0000 | |
| GSE53624 | NRTN | 4902 | 17157 | 0.6388 | 0.0000 | |
| GSE63941 | NRTN | 4902 | 210683_at | 0.4447 | 0.3853 | |
| GSE77861 | NRTN | 4902 | 210683_at | -0.2630 | 0.1086 | |
| GSE97050 | NRTN | 4902 | A_23_P90359 | 0.5601 | 0.1404 | |
| SRP064894 | NRTN | 4902 | RNAseq | -1.4338 | 0.0003 | |
| SRP133303 | NRTN | 4902 | RNAseq | -2.3747 | 0.0000 | |
| SRP159526 | NRTN | 4902 | RNAseq | 0.7338 | 0.4030 | |
| SRP219564 | NRTN | 4902 | RNAseq | -1.4895 | 0.0058 | |
| TCGA | NRTN | 4902 | RNAseq | -0.8829 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by NRTN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NRTN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NRTN | 4902 | 5 | 3 | 22 | |
| GSE20123 | NRTN | 4902 | 4 | 2 | 24 | |
| GSE43470 | NRTN | 4902 | 2 | 6 | 35 | |
| GSE46452 | NRTN | 4902 | 47 | 1 | 11 | |
| GSE47630 | NRTN | 4902 | 5 | 7 | 28 | |
| GSE54993 | NRTN | 4902 | 16 | 3 | 51 | |
| GSE54994 | NRTN | 4902 | 6 | 16 | 31 | |
| GSE60625 | NRTN | 4902 | 9 | 0 | 2 | |
| GSE74703 | NRTN | 4902 | 2 | 4 | 30 | |
| GSE74704 | NRTN | 4902 | 1 | 2 | 17 | |
| TCGA | NRTN | 4902 | 10 | 17 | 69 |
Total number of gains: 107; Total number of losses: 61; Total Number of normals: 320.
Somatic mutations of NRTN:
Generating mutation plots.
Highly correlated genes for NRTN:
Showing top 20/81 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NRTN | TMEM63B | 0.729146 | 3 | 0 | 3 |
| NRTN | TCEAL2 | 0.701962 | 3 | 0 | 3 |
| NRTN | CNST | 0.691431 | 3 | 0 | 3 |
| NRTN | SLC26A5 | 0.681074 | 3 | 0 | 3 |
| NRTN | OR2T12 | 0.678162 | 3 | 0 | 3 |
| NRTN | EPHA7 | 0.664748 | 3 | 0 | 3 |
| NRTN | HAND2-AS1 | 0.662101 | 4 | 0 | 4 |
| NRTN | KLHL17 | 0.661963 | 4 | 0 | 4 |
| NRTN | SETMAR | 0.654238 | 4 | 0 | 3 |
| NRTN | ID4 | 0.653549 | 3 | 0 | 3 |
| NRTN | LSM11 | 0.653413 | 3 | 0 | 3 |
| NRTN | CRBN | 0.650253 | 3 | 0 | 3 |
| NRTN | UTS2R | 0.647933 | 3 | 0 | 3 |
| NRTN | TSNARE1 | 0.646383 | 3 | 0 | 3 |
| NRTN | PVT1 | 0.642866 | 3 | 0 | 3 |
| NRTN | AMH | 0.639504 | 3 | 0 | 3 |
| NRTN | OBP2A | 0.633306 | 3 | 0 | 3 |
| NRTN | THBS4 | 0.627494 | 4 | 0 | 4 |
| NRTN | LIPE-AS1 | 0.627061 | 3 | 0 | 3 |
| NRTN | LINC01220 | 0.623157 | 3 | 0 | 3 |
For details and further investigation, click here
