| Full name: neurotensin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q21.31 | ||
| Entrez ID: 4922 | HGNC ID: HGNC:8038 | Ensembl Gene: ENSG00000133636 | OMIM ID: 162650 |
| Drug and gene relationship at DGIdb | |||
Expression of NTS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NTS | 4922 | 206291_at | 0.5179 | 0.8878 | |
| GSE20347 | NTS | 4922 | 206291_at | 4.1979 | 0.0003 | |
| GSE23400 | NTS | 4922 | 206291_at | 0.9718 | 0.0119 | |
| GSE26886 | NTS | 4922 | 206291_at | 0.5788 | 0.2949 | |
| GSE29001 | NTS | 4922 | 206291_at | 0.7747 | 0.4329 | |
| GSE38129 | NTS | 4922 | 206291_at | 3.5608 | 0.0001 | |
| GSE45670 | NTS | 4922 | 206291_at | 2.5112 | 0.1093 | |
| GSE53622 | NTS | 4922 | 131975 | 0.7122 | 0.1407 | |
| GSE53624 | NTS | 4922 | 131975 | 0.6627 | 0.0760 | |
| GSE63941 | NTS | 4922 | 206291_at | 2.0558 | 0.2860 | |
| GSE77861 | NTS | 4922 | 206291_at | 1.4658 | 0.6002 | |
| GSE97050 | NTS | 4922 | A_23_P36882 | 2.0525 | 0.1856 | |
| SRP007169 | NTS | 4922 | RNAseq | 5.3027 | 0.0000 | |
| SRP133303 | NTS | 4922 | RNAseq | 2.4105 | 0.0780 | |
| SRP159526 | NTS | 4922 | RNAseq | 6.8716 | 0.0000 | |
| TCGA | NTS | 4922 | RNAseq | 0.5913 | 0.3806 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by NTS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NTS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NTS | 4922 | 3 | 3 | 24 | |
| GSE20123 | NTS | 4922 | 3 | 3 | 24 | |
| GSE43470 | NTS | 4922 | 3 | 1 | 39 | |
| GSE46452 | NTS | 4922 | 9 | 1 | 49 | |
| GSE47630 | NTS | 4922 | 10 | 1 | 29 | |
| GSE54993 | NTS | 4922 | 0 | 5 | 65 | |
| GSE54994 | NTS | 4922 | 7 | 1 | 45 | |
| GSE60625 | NTS | 4922 | 0 | 0 | 11 | |
| GSE74703 | NTS | 4922 | 3 | 1 | 32 | |
| GSE74704 | NTS | 4922 | 1 | 3 | 16 | |
| TCGA | NTS | 4922 | 19 | 10 | 67 |
Total number of gains: 58; Total number of losses: 29; Total Number of normals: 401.
Somatic mutations of NTS:
Generating mutation plots.
Highly correlated genes for NTS:
Showing top 20/58 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NTS | DEPDC5 | 0.6473 | 3 | 0 | 3 |
| NTS | LRRC4 | 0.630524 | 5 | 0 | 4 |
| NTS | MAGED1 | 0.626284 | 4 | 0 | 3 |
| NTS | OAZ1 | 0.622372 | 4 | 0 | 3 |
| NTS | RASSF9 | 0.622193 | 11 | 0 | 10 |
| NTS | SLC12A9 | 0.611411 | 4 | 0 | 3 |
| NTS | LMO4 | 0.606578 | 5 | 0 | 4 |
| NTS | C15orf61 | 0.604017 | 3 | 0 | 3 |
| NTS | CD9 | 0.600578 | 4 | 0 | 3 |
| NTS | BDNF | 0.597497 | 6 | 0 | 4 |
| NTS | B4GALT4 | 0.592521 | 10 | 0 | 7 |
| NTS | LINC01133 | 0.587353 | 4 | 0 | 3 |
| NTS | GLS2 | 0.584012 | 4 | 0 | 3 |
| NTS | EPHB1 | 0.578092 | 7 | 0 | 5 |
| NTS | ARHGAP26 | 0.573791 | 6 | 0 | 4 |
| NTS | ECSIT | 0.569635 | 4 | 0 | 3 |
| NTS | ABCC5 | 0.568229 | 10 | 0 | 7 |
| NTS | JAKMIP2 | 0.566175 | 6 | 0 | 4 |
| NTS | NTRK2 | 0.561882 | 9 | 0 | 8 |
| NTS | SOX2-OT | 0.560218 | 7 | 0 | 4 |
For details and further investigation, click here
