| Full name: Rho GTPase activating protein 26 | Alias Symbol: GRAF|KIAA0621|OPHN1L|OPHN1L1 | ||
| Type: protein-coding gene | Cytoband: 5q31.3 | ||
| Entrez ID: 23092 | HGNC ID: HGNC:17073 | Ensembl Gene: ENSG00000145819 | OMIM ID: 605370 |
| Drug and gene relationship at DGIdb | |||
Expression of ARHGAP26:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARHGAP26 | 23092 | 205068_s_at | 0.0851 | 0.8516 | |
| GSE20347 | ARHGAP26 | 23092 | 205068_s_at | 0.2089 | 0.2864 | |
| GSE23400 | ARHGAP26 | 23092 | 205068_s_at | -0.0125 | 0.8539 | |
| GSE26886 | ARHGAP26 | 23092 | 205068_s_at | -0.3093 | 0.1994 | |
| GSE29001 | ARHGAP26 | 23092 | 205068_s_at | 0.0063 | 0.9862 | |
| GSE38129 | ARHGAP26 | 23092 | 205068_s_at | 0.0538 | 0.7846 | |
| GSE45670 | ARHGAP26 | 23092 | 205068_s_at | -0.0125 | 0.9689 | |
| GSE53622 | ARHGAP26 | 23092 | 13751 | -0.9277 | 0.0000 | |
| GSE53624 | ARHGAP26 | 23092 | 13751 | -0.7035 | 0.0000 | |
| GSE63941 | ARHGAP26 | 23092 | 205068_s_at | 0.9096 | 0.1143 | |
| GSE77861 | ARHGAP26 | 23092 | 205068_s_at | 0.3108 | 0.3940 | |
| GSE97050 | ARHGAP26 | 23092 | A_33_P3228305 | 0.2275 | 0.4762 | |
| SRP007169 | ARHGAP26 | 23092 | RNAseq | 0.2773 | 0.5068 | |
| SRP008496 | ARHGAP26 | 23092 | RNAseq | 0.1053 | 0.7397 | |
| SRP064894 | ARHGAP26 | 23092 | RNAseq | 0.0261 | 0.9065 | |
| SRP133303 | ARHGAP26 | 23092 | RNAseq | -0.4600 | 0.0266 | |
| SRP159526 | ARHGAP26 | 23092 | RNAseq | -0.2889 | 0.4658 | |
| SRP193095 | ARHGAP26 | 23092 | RNAseq | 0.0312 | 0.8957 | |
| SRP219564 | ARHGAP26 | 23092 | RNAseq | 0.1587 | 0.6618 | |
| TCGA | ARHGAP26 | 23092 | RNAseq | -0.4134 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ARHGAP26 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARHGAP26:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARHGAP26 | 23092 | 1 | 12 | 17 | |
| GSE20123 | ARHGAP26 | 23092 | 1 | 12 | 17 | |
| GSE43470 | ARHGAP26 | 23092 | 2 | 10 | 31 | |
| GSE46452 | ARHGAP26 | 23092 | 0 | 27 | 32 | |
| GSE47630 | ARHGAP26 | 23092 | 0 | 20 | 20 | |
| GSE54993 | ARHGAP26 | 23092 | 9 | 1 | 60 | |
| GSE54994 | ARHGAP26 | 23092 | 2 | 14 | 37 | |
| GSE60625 | ARHGAP26 | 23092 | 0 | 0 | 11 | |
| GSE74703 | ARHGAP26 | 23092 | 2 | 7 | 27 | |
| GSE74704 | ARHGAP26 | 23092 | 1 | 6 | 13 | |
| TCGA | ARHGAP26 | 23092 | 3 | 38 | 55 |
Total number of gains: 21; Total number of losses: 147; Total Number of normals: 320.
Somatic mutations of ARHGAP26:
Generating mutation plots.
Highly correlated genes for ARHGAP26:
Showing top 20/102 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARHGAP26 | PLRG1 | 0.653461 | 4 | 0 | 3 |
| ARHGAP26 | SELP | 0.635397 | 3 | 0 | 3 |
| ARHGAP26 | EGF | 0.608758 | 3 | 0 | 3 |
| ARHGAP26 | PIK3AP1 | 0.605952 | 3 | 0 | 3 |
| ARHGAP26 | SEC11C | 0.604868 | 4 | 0 | 4 |
| ARHGAP26 | CD5 | 0.602415 | 4 | 0 | 3 |
| ARHGAP26 | APOL2 | 0.596184 | 3 | 0 | 3 |
| ARHGAP26 | SH2B2 | 0.595241 | 3 | 0 | 3 |
| ARHGAP26 | SPPL3 | 0.59375 | 3 | 0 | 3 |
| ARHGAP26 | LTF | 0.592559 | 7 | 0 | 4 |
| ARHGAP26 | NSUN7 | 0.591826 | 3 | 0 | 3 |
| ARHGAP26 | SCML4 | 0.580514 | 4 | 0 | 3 |
| ARHGAP26 | ARHGAP9 | 0.58046 | 5 | 0 | 4 |
| ARHGAP26 | SLFNL1 | 0.578011 | 3 | 0 | 3 |
| ARHGAP26 | RAMP3 | 0.577696 | 3 | 0 | 3 |
| ARHGAP26 | CXCL16 | 0.577632 | 3 | 0 | 3 |
| ARHGAP26 | NTS | 0.573791 | 6 | 0 | 4 |
| ARHGAP26 | CCDC97 | 0.573149 | 4 | 0 | 3 |
| ARHGAP26 | PCGF5 | 0.572856 | 4 | 0 | 3 |
| ARHGAP26 | HLA-DQB1 | 0.571746 | 3 | 0 | 3 |
For details and further investigation, click here
