| Full name: signaling lymphocytic activation molecule family member 1 | Alias Symbol: CD150 | ||
| Type: protein-coding gene | Cytoband: 1q23.3 | ||
| Entrez ID: 6504 | HGNC ID: HGNC:10903 | Ensembl Gene: ENSG00000117090 | OMIM ID: 603492 |
| Drug and gene relationship at DGIdb | |||
SLAMF1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05162 | Measles |
Expression of SLAMF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLAMF1 | 6504 | 239427_at | -0.3641 | 0.3897 | |
| GSE20347 | SLAMF1 | 6504 | 206181_at | -0.0548 | 0.5739 | |
| GSE23400 | SLAMF1 | 6504 | 206181_at | 0.0082 | 0.8645 | |
| GSE26886 | SLAMF1 | 6504 | 239427_at | -0.2248 | 0.0339 | |
| GSE29001 | SLAMF1 | 6504 | 206181_at | -0.0558 | 0.7519 | |
| GSE38129 | SLAMF1 | 6504 | 206181_at | -0.0397 | 0.8079 | |
| GSE45670 | SLAMF1 | 6504 | 239427_at | -0.0671 | 0.6106 | |
| GSE53622 | SLAMF1 | 6504 | 77479 | -0.0515 | 0.7045 | |
| GSE53624 | SLAMF1 | 6504 | 77479 | -0.1080 | 0.4714 | |
| GSE63941 | SLAMF1 | 6504 | 239427_at | 0.2269 | 0.2108 | |
| GSE77861 | SLAMF1 | 6504 | 239427_at | -0.0726 | 0.5309 | |
| GSE97050 | SLAMF1 | 6504 | A_33_P3352827 | 0.7339 | 0.1995 | |
| SRP064894 | SLAMF1 | 6504 | RNAseq | 0.1199 | 0.6785 | |
| SRP133303 | SLAMF1 | 6504 | RNAseq | -0.3990 | 0.1105 | |
| SRP159526 | SLAMF1 | 6504 | RNAseq | -0.7031 | 0.4256 | |
| SRP193095 | SLAMF1 | 6504 | RNAseq | -0.1524 | 0.5707 | |
| SRP219564 | SLAMF1 | 6504 | RNAseq | 0.1107 | 0.8305 | |
| TCGA | SLAMF1 | 6504 | RNAseq | -0.1703 | 0.5492 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLAMF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLAMF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLAMF1 | 6504 | 10 | 0 | 20 | |
| GSE20123 | SLAMF1 | 6504 | 10 | 0 | 20 | |
| GSE43470 | SLAMF1 | 6504 | 7 | 2 | 34 | |
| GSE46452 | SLAMF1 | 6504 | 2 | 1 | 56 | |
| GSE47630 | SLAMF1 | 6504 | 14 | 0 | 26 | |
| GSE54993 | SLAMF1 | 6504 | 0 | 6 | 64 | |
| GSE54994 | SLAMF1 | 6504 | 16 | 0 | 37 | |
| GSE60625 | SLAMF1 | 6504 | 0 | 0 | 11 | |
| GSE74703 | SLAMF1 | 6504 | 7 | 2 | 27 | |
| GSE74704 | SLAMF1 | 6504 | 4 | 0 | 16 | |
| TCGA | SLAMF1 | 6504 | 45 | 3 | 48 |
Total number of gains: 115; Total number of losses: 14; Total Number of normals: 359.
Somatic mutations of SLAMF1:
Generating mutation plots.
Highly correlated genes for SLAMF1:
Showing top 20/399 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLAMF1 | SNX20 | 0.732991 | 4 | 0 | 3 |
| SLAMF1 | CD48 | 0.719237 | 9 | 0 | 9 |
| SLAMF1 | GIMAP5 | 0.71707 | 4 | 0 | 4 |
| SLAMF1 | CYTIP | 0.711603 | 8 | 0 | 8 |
| SLAMF1 | GPR141 | 0.702393 | 3 | 0 | 3 |
| SLAMF1 | TNFAIP8L2 | 0.700308 | 6 | 0 | 5 |
| SLAMF1 | MPEG1 | 0.699836 | 4 | 0 | 4 |
| SLAMF1 | ABHD14B | 0.69709 | 3 | 0 | 3 |
| SLAMF1 | ARHGAP15 | 0.693275 | 4 | 0 | 3 |
| SLAMF1 | TOM1 | 0.687913 | 3 | 0 | 3 |
| SLAMF1 | ITK | 0.684867 | 10 | 0 | 9 |
| SLAMF1 | ZNF862 | 0.684716 | 3 | 0 | 3 |
| SLAMF1 | GIMAP1 | 0.680839 | 5 | 0 | 4 |
| SLAMF1 | ARHGAP9 | 0.680165 | 5 | 0 | 5 |
| SLAMF1 | DTD1 | 0.679355 | 3 | 0 | 3 |
| SLAMF1 | SLAMF6 | 0.678056 | 7 | 0 | 6 |
| SLAMF1 | GIMAP7 | 0.677496 | 5 | 0 | 5 |
| SLAMF1 | INPP5D | 0.677241 | 9 | 0 | 8 |
| SLAMF1 | LCP1 | 0.67689 | 7 | 0 | 7 |
| SLAMF1 | APIP | 0.676204 | 3 | 0 | 3 |
For details and further investigation, click here
