NUDT21

 

Full name: nudix hydrolase 21 Alias Symbol: CFIM25
Type: protein-coding gene Cytoband: 16q13
Entrez ID: 11051 HGNC ID: HGNC:13870 Ensembl Gene: ENSG00000167005 OMIM ID: 604978
Drug and gene relationship at DGIdb

 

Expression of NUDT21:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NUDT21 11051 224830_at 0.3205 0.5529
GSE20347 NUDT21 11051 202697_at 0.0061 0.9863
GSE23400 NUDT21 11051 202697_at 0.3779 0.0020
GSE26886 NUDT21 11051 224830_at -0.5028 0.0326
GSE29001 NUDT21 11051 202697_at -0.4623 0.2308
GSE38129 NUDT21 11051 202697_at 0.3537 0.1454
GSE45670 NUDT21 11051 224830_at -0.0494 0.8512
GSE53622 NUDT21 11051 39621 0.1913 0.0003
GSE53624 NUDT21 11051 39621 0.1307 0.0295
GSE63941 NUDT21 11051 202697_at 2.1285 0.0009
GSE77861 NUDT21 11051 224830_at 0.2962 0.3383
GSE97050 NUDT21 11051 A_33_P3418942 0.0881 0.7234
SRP007169 NUDT21 11051 RNAseq 0.8793 0.0129
SRP008496 NUDT21 11051 RNAseq 0.9656 0.0000
SRP064894 NUDT21 11051 RNAseq -0.1118 0.5013
SRP133303 NUDT21 11051 RNAseq 0.3797 0.0286
SRP159526 NUDT21 11051 RNAseq 0.1631 0.4592
SRP193095 NUDT21 11051 RNAseq 0.0470 0.6923
SRP219564 NUDT21 11051 RNAseq -0.0062 0.9846
TCGA NUDT21 11051 RNAseq 0.1303 0.0036

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by NUDT21 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of NUDT21:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NUDT21 11051 5 0 25
GSE20123 NUDT21 11051 5 0 25
GSE43470 NUDT21 11051 2 7 34
GSE46452 NUDT21 11051 38 1 20
GSE47630 NUDT21 11051 10 8 22
GSE54993 NUDT21 11051 2 4 64
GSE54994 NUDT21 11051 7 10 36
GSE60625 NUDT21 11051 4 0 7
GSE74703 NUDT21 11051 2 4 30
GSE74704 NUDT21 11051 4 0 16
TCGA NUDT21 11051 25 12 59

Total number of gains: 104; Total number of losses: 46; Total Number of normals: 338.  


 

Somatic mutations of NUDT21:

 

Generating mutation plots.

 

Highly correlated genes for NUDT21:

 

Showing top 20/790 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NUDT21TCEANC20.809426303
NUDT21CETN30.802185303
NUDT21AGL0.778886303
NUDT21HERPUD10.762973303
NUDT21S1PR50.75901303
NUDT21GAPT0.748329303
NUDT21MRPL380.746395303
NUDT21EME10.744242303
NUDT21ZCCHC80.73589303
NUDT21MASTL0.735366303
NUDT21TRUB10.726742404
NUDT21TTI20.715212404
NUDT21FAM122A0.711752303
NUDT21TNKS20.707973303
NUDT21CALCRL0.705266303
NUDT21E2F20.700027303
NUDT21TBC1D80.697978303
NUDT21RNF144B0.696828303
NUDT21CIAPIN10.6958761009
NUDT21RIOK20.690992403

For details and further investigation, click here