| Full name: nudix hydrolase 8 | Alias Symbol: FLJ41567 | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 254552 | HGNC ID: HGNC:8055 | Ensembl Gene: ENSG00000167799 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NUDT8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | NUDT8 | 254552 | 31273 | -0.6022 | 0.0000 | |
| GSE53624 | NUDT8 | 254552 | 31273 | -0.7020 | 0.0000 | |
| GSE97050 | NUDT8 | 254552 | A_33_P3384932 | 0.1764 | 0.4650 | |
| SRP007169 | NUDT8 | 254552 | RNAseq | -1.9344 | 0.0012 | |
| SRP064894 | NUDT8 | 254552 | RNAseq | -1.9039 | 0.0000 | |
| SRP133303 | NUDT8 | 254552 | RNAseq | -0.9315 | 0.0061 | |
| SRP159526 | NUDT8 | 254552 | RNAseq | -1.0765 | 0.0296 | |
| SRP193095 | NUDT8 | 254552 | RNAseq | -0.6355 | 0.0083 | |
| SRP219564 | NUDT8 | 254552 | RNAseq | -0.5355 | 0.4870 | |
| TCGA | NUDT8 | 254552 | RNAseq | 0.4716 | 0.0012 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by NUDT8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUDT8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUDT8 | 254552 | 10 | 3 | 17 | |
| GSE20123 | NUDT8 | 254552 | 10 | 3 | 17 | |
| GSE43470 | NUDT8 | 254552 | 5 | 2 | 36 | |
| GSE46452 | NUDT8 | 254552 | 14 | 3 | 42 | |
| GSE47630 | NUDT8 | 254552 | 8 | 5 | 27 | |
| GSE54993 | NUDT8 | 254552 | 3 | 1 | 66 | |
| GSE54994 | NUDT8 | 254552 | 13 | 4 | 36 | |
| GSE60625 | NUDT8 | 254552 | 0 | 3 | 8 | |
| GSE74703 | NUDT8 | 254552 | 4 | 1 | 31 | |
| GSE74704 | NUDT8 | 254552 | 8 | 1 | 11 | |
| TCGA | NUDT8 | 254552 | 36 | 9 | 51 |
Total number of gains: 111; Total number of losses: 35; Total Number of normals: 342.
Somatic mutations of NUDT8:
Generating mutation plots.
Highly correlated genes for NUDT8:
Showing top 20/64 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUDT8 | MAPK13 | 0.757243 | 3 | 0 | 3 |
| NUDT8 | SEMA3F | 0.746305 | 3 | 0 | 3 |
| NUDT8 | PLEKHN1 | 0.744097 | 3 | 0 | 3 |
| NUDT8 | PTK6 | 0.728904 | 3 | 0 | 3 |
| NUDT8 | GGT6 | 0.722636 | 3 | 0 | 3 |
| NUDT8 | CD164L2 | 0.70724 | 3 | 0 | 3 |
| NUDT8 | TEN1 | 0.692782 | 3 | 0 | 3 |
| NUDT8 | TPRN | 0.689733 | 3 | 0 | 3 |
| NUDT8 | EPHA1 | 0.687269 | 3 | 0 | 3 |
| NUDT8 | PCDH1 | 0.681209 | 3 | 0 | 3 |
| NUDT8 | TREH | 0.681012 | 4 | 0 | 3 |
| NUDT8 | OR10G8 | 0.678924 | 3 | 0 | 3 |
| NUDT8 | KRT83 | 0.67833 | 3 | 0 | 3 |
| NUDT8 | SLC2A8 | 0.677925 | 3 | 0 | 3 |
| NUDT8 | MAST4 | 0.67239 | 3 | 0 | 3 |
| NUDT8 | SERINC5 | 0.666447 | 3 | 0 | 3 |
| NUDT8 | HES5 | 0.664316 | 3 | 0 | 3 |
| NUDT8 | MALL | 0.663973 | 3 | 0 | 3 |
| NUDT8 | NCCRP1 | 0.662655 | 3 | 0 | 3 |
| NUDT8 | EPS8L2 | 0.660457 | 4 | 0 | 4 |
For details and further investigation, click here
