| Full name: olfactory receptor family 8 subfamily B member 8 | Alias Symbol: TPCR85 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 26493 | HGNC ID: HGNC:8477 | Ensembl Gene: ENSG00000197125 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
OR8B8 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR8B8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OR8B8 | 26493 | 1555212_at | 0.0445 | 0.8797 | |
| GSE26886 | OR8B8 | 26493 | 1555212_at | -0.1928 | 0.0360 | |
| GSE45670 | OR8B8 | 26493 | 1555212_at | 0.0678 | 0.5525 | |
| GSE53622 | OR8B8 | 26493 | 10841 | 0.1102 | 0.4240 | |
| GSE53624 | OR8B8 | 26493 | 10841 | -0.0129 | 0.9485 | |
| GSE63941 | OR8B8 | 26493 | 1555212_at | -0.2007 | 0.1392 | |
| GSE77861 | OR8B8 | 26493 | 1555212_at | -0.1958 | 0.1039 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OR8B8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR8B8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR8B8 | 26493 | 0 | 13 | 17 | |
| GSE20123 | OR8B8 | 26493 | 0 | 13 | 17 | |
| GSE43470 | OR8B8 | 26493 | 3 | 6 | 34 | |
| GSE46452 | OR8B8 | 26493 | 3 | 26 | 30 | |
| GSE47630 | OR8B8 | 26493 | 2 | 19 | 19 | |
| GSE54993 | OR8B8 | 26493 | 10 | 0 | 60 | |
| GSE54994 | OR8B8 | 26493 | 5 | 19 | 29 | |
| GSE60625 | OR8B8 | 26493 | 0 | 3 | 8 | |
| GSE74703 | OR8B8 | 26493 | 2 | 4 | 30 | |
| GSE74704 | OR8B8 | 26493 | 0 | 9 | 11 | |
| TCGA | OR8B8 | 26493 | 6 | 50 | 40 |
Total number of gains: 31; Total number of losses: 162; Total Number of normals: 295.
Somatic mutations of OR8B8:
Generating mutation plots.
Highly correlated genes for OR8B8:
Showing top 20/40 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR8B8 | PAX4 | 0.636067 | 3 | 0 | 3 |
| OR8B8 | TBXA2R | 0.623582 | 3 | 0 | 3 |
| OR8B8 | DDC | 0.62342 | 3 | 0 | 3 |
| OR8B8 | ZNF70 | 0.616683 | 3 | 0 | 3 |
| OR8B8 | IL27 | 0.612573 | 3 | 0 | 3 |
| OR8B8 | CRH | 0.606815 | 3 | 0 | 3 |
| OR8B8 | PGLYRP2 | 0.60138 | 3 | 0 | 3 |
| OR8B8 | LINC00606 | 0.597718 | 3 | 0 | 3 |
| OR8B8 | LINC00661 | 0.591036 | 4 | 0 | 3 |
| OR8B8 | HKDC1 | 0.5856 | 4 | 0 | 4 |
| OR8B8 | NT5DC2 | 0.577452 | 3 | 0 | 3 |
| OR8B8 | SLC6A2 | 0.575528 | 4 | 0 | 3 |
| OR8B8 | LINC00221 | 0.573541 | 3 | 0 | 3 |
| OR8B8 | FTHL17 | 0.573419 | 3 | 0 | 3 |
| OR8B8 | NOP14-AS1 | 0.573117 | 4 | 0 | 3 |
| OR8B8 | LINC01015 | 0.569612 | 4 | 0 | 3 |
| OR8B8 | ADAMTSL5 | 0.565144 | 5 | 0 | 4 |
| OR8B8 | GBX2 | 0.564188 | 4 | 0 | 3 |
| OR8B8 | TSGA10IP | 0.55537 | 4 | 0 | 3 |
| OR8B8 | C8orf74 | 0.555265 | 4 | 0 | 3 |
For details and further investigation, click here
