| Full name: insulin like growth factor 2 mRNA binding protein 2 | Alias Symbol: IMP-2 | ||
| Type: protein-coding gene | Cytoband: 3q27.2 | ||
| Entrez ID: 10644 | HGNC ID: HGNC:28867 | Ensembl Gene: ENSG00000073792 | OMIM ID: 608289 |
| Drug and gene relationship at DGIdb | |||
Expression of IGF2BP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IGF2BP2 | 10644 | 218847_at | 1.5748 | 0.0301 | |
| GSE20347 | IGF2BP2 | 10644 | 218847_at | 2.2233 | 0.0000 | |
| GSE23400 | IGF2BP2 | 10644 | 218847_at | 1.6276 | 0.0000 | |
| GSE26886 | IGF2BP2 | 10644 | 218847_at | 2.6741 | 0.0000 | |
| GSE29001 | IGF2BP2 | 10644 | 218847_at | 1.4729 | 0.0021 | |
| GSE38129 | IGF2BP2 | 10644 | 218847_at | 2.0587 | 0.0000 | |
| GSE45670 | IGF2BP2 | 10644 | 218847_at | 2.1620 | 0.0000 | |
| GSE53622 | IGF2BP2 | 10644 | 113519 | 2.7136 | 0.0000 | |
| GSE53624 | IGF2BP2 | 10644 | 113519 | 2.5875 | 0.0000 | |
| GSE63941 | IGF2BP2 | 10644 | 218847_at | -0.5876 | 0.3092 | |
| GSE77861 | IGF2BP2 | 10644 | 218847_at | 3.0600 | 0.0005 | |
| GSE97050 | IGF2BP2 | 10644 | A_33_P3242973 | 2.5838 | 0.0837 | |
| SRP007169 | IGF2BP2 | 10644 | RNAseq | 6.0396 | 0.0000 | |
| SRP008496 | IGF2BP2 | 10644 | RNAseq | 5.4216 | 0.0000 | |
| SRP064894 | IGF2BP2 | 10644 | RNAseq | 2.9301 | 0.0000 | |
| SRP133303 | IGF2BP2 | 10644 | RNAseq | 2.7403 | 0.0000 | |
| SRP159526 | IGF2BP2 | 10644 | RNAseq | 3.9256 | 0.0000 | |
| SRP193095 | IGF2BP2 | 10644 | RNAseq | 2.0270 | 0.0000 | |
| SRP219564 | IGF2BP2 | 10644 | RNAseq | 3.0648 | 0.0000 | |
| TCGA | IGF2BP2 | 10644 | RNAseq | 0.4025 | 0.0034 |
Upregulated datasets: 17; Downregulated datasets: 0.
Survival by IGF2BP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IGF2BP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IGF2BP2 | 10644 | 25 | 0 | 5 | |
| GSE20123 | IGF2BP2 | 10644 | 25 | 0 | 5 | |
| GSE43470 | IGF2BP2 | 10644 | 23 | 0 | 20 | |
| GSE46452 | IGF2BP2 | 10644 | 19 | 1 | 39 | |
| GSE47630 | IGF2BP2 | 10644 | 27 | 2 | 11 | |
| GSE54993 | IGF2BP2 | 10644 | 1 | 19 | 50 | |
| GSE54994 | IGF2BP2 | 10644 | 40 | 0 | 13 | |
| GSE60625 | IGF2BP2 | 10644 | 0 | 6 | 5 | |
| GSE74703 | IGF2BP2 | 10644 | 20 | 0 | 16 | |
| GSE74704 | IGF2BP2 | 10644 | 17 | 0 | 3 | |
| TCGA | IGF2BP2 | 10644 | 77 | 0 | 19 |
Total number of gains: 274; Total number of losses: 28; Total Number of normals: 186.
Somatic mutations of IGF2BP2:
Generating mutation plots.
Highly correlated genes for IGF2BP2:
Showing top 20/1729 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IGF2BP2 | UHRF1 | 0.813543 | 7 | 0 | 7 |
| IGF2BP2 | MMP1 | 0.791801 | 11 | 0 | 11 |
| IGF2BP2 | WDR66 | 0.782166 | 7 | 0 | 7 |
| IGF2BP2 | CTHRC1 | 0.777561 | 7 | 0 | 7 |
| IGF2BP2 | CMSS1 | 0.773493 | 6 | 0 | 6 |
| IGF2BP2 | XPR1 | 0.769566 | 7 | 0 | 7 |
| IGF2BP2 | SLC19A1 | 0.766977 | 3 | 0 | 3 |
| IGF2BP2 | KIF26B | 0.766228 | 5 | 0 | 5 |
| IGF2BP2 | EME1 | 0.765788 | 5 | 0 | 5 |
| IGF2BP2 | KIF14 | 0.763559 | 11 | 0 | 11 |
| IGF2BP2 | ORC6 | 0.763459 | 10 | 0 | 10 |
| IGF2BP2 | ITPR3 | 0.762708 | 11 | 0 | 11 |
| IGF2BP2 | FMNL2 | 0.761375 | 8 | 0 | 8 |
| IGF2BP2 | LRRC8D | 0.760553 | 11 | 0 | 11 |
| IGF2BP2 | TRIP13 | 0.758061 | 11 | 0 | 10 |
| IGF2BP2 | CDCA2 | 0.755546 | 5 | 0 | 5 |
| IGF2BP2 | PLAU | 0.755127 | 11 | 0 | 10 |
| IGF2BP2 | FAM89A | 0.75476 | 3 | 0 | 3 |
| IGF2BP2 | FSCN1 | 0.754133 | 11 | 0 | 10 |
| IGF2BP2 | PTHLH | 0.753713 | 10 | 0 | 10 |
For details and further investigation, click here
