| Full name: odd-skipped related transciption factor 2 | Alias Symbol: FLJ90037 | ||
| Type: protein-coding gene | Cytoband: 8q22.2 | ||
| Entrez ID: 116039 | HGNC ID: HGNC:15830 | Ensembl Gene: ENSG00000164920 | OMIM ID: 611297 |
| Drug and gene relationship at DGIdb | |||
Expression of OSR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSR2 | 116039 | 213568_at | 0.1503 | 0.8657 | |
| GSE20347 | OSR2 | 116039 | 213568_at | 1.4693 | 0.0000 | |
| GSE23400 | OSR2 | 116039 | 213568_at | 0.1827 | 0.0706 | |
| GSE26886 | OSR2 | 116039 | 213568_at | 2.8956 | 0.0000 | |
| GSE29001 | OSR2 | 116039 | 213568_at | 1.3505 | 0.0061 | |
| GSE38129 | OSR2 | 116039 | 213568_at | 0.7692 | 0.0204 | |
| GSE45670 | OSR2 | 116039 | 213568_at | -1.5408 | 0.0007 | |
| GSE53622 | OSR2 | 116039 | 9283 | -0.1023 | 0.5957 | |
| GSE53624 | OSR2 | 116039 | 9283 | 0.4043 | 0.0020 | |
| GSE63941 | OSR2 | 116039 | 213568_at | -1.9275 | 0.0758 | |
| GSE77861 | OSR2 | 116039 | 213568_at | 1.1108 | 0.0103 | |
| GSE97050 | OSR2 | 116039 | A_24_P55496 | 0.5791 | 0.3872 | |
| SRP007169 | OSR2 | 116039 | RNAseq | 2.4505 | 0.0043 | |
| SRP064894 | OSR2 | 116039 | RNAseq | -0.5932 | 0.1209 | |
| SRP133303 | OSR2 | 116039 | RNAseq | -1.0933 | 0.0000 | |
| SRP159526 | OSR2 | 116039 | RNAseq | -0.5968 | 0.1561 | |
| SRP219564 | OSR2 | 116039 | RNAseq | -0.1114 | 0.8447 | |
| TCGA | OSR2 | 116039 | RNAseq | 0.3411 | 0.0253 |
Upregulated datasets: 5; Downregulated datasets: 2.
Survival by OSR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OSR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSR2 | 116039 | 16 | 0 | 14 | |
| GSE20123 | OSR2 | 116039 | 17 | 0 | 13 | |
| GSE43470 | OSR2 | 116039 | 21 | 1 | 21 | |
| GSE46452 | OSR2 | 116039 | 23 | 0 | 36 | |
| GSE47630 | OSR2 | 116039 | 24 | 0 | 16 | |
| GSE54993 | OSR2 | 116039 | 0 | 20 | 50 | |
| GSE54994 | OSR2 | 116039 | 38 | 1 | 14 | |
| GSE60625 | OSR2 | 116039 | 0 | 4 | 7 | |
| GSE74703 | OSR2 | 116039 | 18 | 1 | 17 | |
| GSE74704 | OSR2 | 116039 | 12 | 0 | 8 | |
| TCGA | OSR2 | 116039 | 56 | 1 | 39 |
Total number of gains: 225; Total number of losses: 28; Total Number of normals: 235.
Somatic mutations of OSR2:
Generating mutation plots.
Highly correlated genes for OSR2:
Showing top 20/892 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSR2 | BRAT1 | 0.83468 | 3 | 0 | 3 |
| OSR2 | MSTO1 | 0.825499 | 3 | 0 | 3 |
| OSR2 | C12orf75 | 0.817351 | 3 | 0 | 3 |
| OSR2 | NR2C2AP | 0.79832 | 3 | 0 | 3 |
| OSR2 | UBE2T | 0.790465 | 3 | 0 | 3 |
| OSR2 | RTKN | 0.774816 | 3 | 0 | 3 |
| OSR2 | TMEM216 | 0.770395 | 3 | 0 | 3 |
| OSR2 | PPRC1 | 0.76947 | 3 | 0 | 3 |
| OSR2 | ELF4 | 0.759623 | 5 | 0 | 5 |
| OSR2 | NBEAL1 | 0.759068 | 3 | 0 | 3 |
| OSR2 | IKBIP | 0.757295 | 3 | 0 | 3 |
| OSR2 | ATP11C | 0.753528 | 3 | 0 | 3 |
| OSR2 | LSM4 | 0.750211 | 4 | 0 | 4 |
| OSR2 | POP7 | 0.748904 | 3 | 0 | 3 |
| OSR2 | GMNN | 0.742415 | 4 | 0 | 4 |
| OSR2 | C1orf131 | 0.742074 | 3 | 0 | 3 |
| OSR2 | MAN2B1 | 0.737781 | 4 | 0 | 3 |
| OSR2 | FHL1 | 0.735525 | 3 | 0 | 3 |
| OSR2 | FLVCR1 | 0.732171 | 3 | 0 | 3 |
| OSR2 | TMEM132A | 0.730836 | 5 | 0 | 5 |
For details and further investigation, click here
