| Full name: osteoclastogenesis associated transmembrane protein 1 | Alias Symbol: HSPC019|GL | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 28962 | HGNC ID: HGNC:21652 | Ensembl Gene: ENSG00000081087 | OMIM ID: 607649 |
| Drug and gene relationship at DGIdb | |||
Expression of OSTM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSTM1 | 28962 | 218196_at | -0.0175 | 0.9830 | |
| GSE20347 | OSTM1 | 28962 | 218196_at | 0.3141 | 0.2046 | |
| GSE23400 | OSTM1 | 28962 | 218196_at | 0.5477 | 0.0000 | |
| GSE26886 | OSTM1 | 28962 | 218196_at | 0.1240 | 0.6985 | |
| GSE29001 | OSTM1 | 28962 | 218196_at | 0.5696 | 0.0557 | |
| GSE38129 | OSTM1 | 28962 | 218196_at | 0.1543 | 0.5140 | |
| GSE45670 | OSTM1 | 28962 | 218196_at | 0.2022 | 0.4270 | |
| GSE53622 | OSTM1 | 28962 | 87901 | 0.4117 | 0.0000 | |
| GSE53624 | OSTM1 | 28962 | 87901 | 0.4497 | 0.0000 | |
| GSE63941 | OSTM1 | 28962 | 218196_at | -2.6383 | 0.0025 | |
| GSE77861 | OSTM1 | 28962 | 218196_at | 0.6261 | 0.0551 | |
| GSE97050 | OSTM1 | 28962 | A_32_P154830 | 0.1112 | 0.5396 | |
| SRP007169 | OSTM1 | 28962 | RNAseq | 0.3515 | 0.2844 | |
| SRP008496 | OSTM1 | 28962 | RNAseq | 0.4389 | 0.1180 | |
| SRP064894 | OSTM1 | 28962 | RNAseq | 0.7725 | 0.0007 | |
| SRP133303 | OSTM1 | 28962 | RNAseq | 0.6557 | 0.0000 | |
| SRP159526 | OSTM1 | 28962 | RNAseq | 0.1095 | 0.7607 | |
| SRP193095 | OSTM1 | 28962 | RNAseq | 0.4301 | 0.0012 | |
| SRP219564 | OSTM1 | 28962 | RNAseq | 0.2908 | 0.6212 | |
| TCGA | OSTM1 | 28962 | RNAseq | 0.0178 | 0.7792 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by OSTM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OSTM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSTM1 | 28962 | 2 | 3 | 25 | |
| GSE20123 | OSTM1 | 28962 | 2 | 2 | 26 | |
| GSE43470 | OSTM1 | 28962 | 3 | 1 | 39 | |
| GSE46452 | OSTM1 | 28962 | 2 | 11 | 46 | |
| GSE47630 | OSTM1 | 28962 | 9 | 4 | 27 | |
| GSE54993 | OSTM1 | 28962 | 3 | 2 | 65 | |
| GSE54994 | OSTM1 | 28962 | 8 | 8 | 37 | |
| GSE60625 | OSTM1 | 28962 | 0 | 2 | 9 | |
| GSE74703 | OSTM1 | 28962 | 2 | 1 | 33 | |
| GSE74704 | OSTM1 | 28962 | 0 | 0 | 20 | |
| TCGA | OSTM1 | 28962 | 5 | 23 | 68 |
Total number of gains: 36; Total number of losses: 57; Total Number of normals: 395.
Somatic mutations of OSTM1:
Generating mutation plots.
Highly correlated genes for OSTM1:
Showing top 20/364 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSTM1 | FGF7 | 0.654561 | 3 | 0 | 3 |
| OSTM1 | HABP4 | 0.645547 | 3 | 0 | 3 |
| OSTM1 | CTTN | 0.638543 | 3 | 0 | 3 |
| OSTM1 | FEZ2 | 0.638048 | 8 | 0 | 6 |
| OSTM1 | FBN1 | 0.636539 | 8 | 0 | 7 |
| OSTM1 | ARID4B | 0.632757 | 5 | 0 | 4 |
| OSTM1 | SGTB | 0.63257 | 5 | 0 | 4 |
| OSTM1 | CNTN3 | 0.630395 | 3 | 0 | 3 |
| OSTM1 | SEC63 | 0.6292 | 9 | 0 | 7 |
| OSTM1 | ACVR1 | 0.628216 | 11 | 0 | 11 |
| OSTM1 | WFS1 | 0.625823 | 3 | 0 | 3 |
| OSTM1 | C1orf216 | 0.624774 | 10 | 0 | 8 |
| OSTM1 | ABL2 | 0.622179 | 7 | 0 | 5 |
| OSTM1 | TMEM263 | 0.622079 | 6 | 0 | 4 |
| OSTM1 | NID2 | 0.618951 | 9 | 0 | 8 |
| OSTM1 | CHN1 | 0.617798 | 11 | 0 | 9 |
| OSTM1 | CDC42EP3 | 0.615783 | 8 | 0 | 6 |
| OSTM1 | MB21D2 | 0.611731 | 4 | 0 | 3 |
| OSTM1 | CAV2 | 0.610758 | 12 | 0 | 11 |
| OSTM1 | REV3L | 0.609044 | 6 | 0 | 4 |
For details and further investigation, click here
