| Full name: OXA1L mitochondrial inner membrane protein | Alias Symbol: MGC133129|OXA1 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 5018 | HGNC ID: HGNC:8526 | Ensembl Gene: ENSG00000155463 | OMIM ID: 601066 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of OXA1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OXA1L | 5018 | 208717_at | 0.0032 | 0.9968 | |
| GSE20347 | OXA1L | 5018 | 208717_at | 0.0496 | 0.8427 | |
| GSE23400 | OXA1L | 5018 | 208717_at | 0.2674 | 0.0001 | |
| GSE26886 | OXA1L | 5018 | 208717_at | 0.1065 | 0.6753 | |
| GSE29001 | OXA1L | 5018 | 208717_at | 0.0592 | 0.8440 | |
| GSE38129 | OXA1L | 5018 | 208717_at | 0.0953 | 0.5231 | |
| GSE45670 | OXA1L | 5018 | 208717_at | -0.2326 | 0.0944 | |
| GSE53622 | OXA1L | 5018 | 10186 | 0.1542 | 0.0132 | |
| GSE53624 | OXA1L | 5018 | 10186 | 0.0363 | 0.5467 | |
| GSE63941 | OXA1L | 5018 | 208717_at | 2.2843 | 0.0009 | |
| GSE77861 | OXA1L | 5018 | 208717_at | 0.1137 | 0.7313 | |
| GSE97050 | OXA1L | 5018 | A_23_P2998 | 0.2354 | 0.3033 | |
| SRP007169 | OXA1L | 5018 | RNAseq | 0.1020 | 0.7277 | |
| SRP008496 | OXA1L | 5018 | RNAseq | -0.1610 | 0.4915 | |
| SRP064894 | OXA1L | 5018 | RNAseq | 0.3013 | 0.0381 | |
| SRP133303 | OXA1L | 5018 | RNAseq | 0.1004 | 0.6147 | |
| SRP159526 | OXA1L | 5018 | RNAseq | -0.0509 | 0.7880 | |
| SRP193095 | OXA1L | 5018 | RNAseq | -0.1525 | 0.1678 | |
| SRP219564 | OXA1L | 5018 | RNAseq | 0.1768 | 0.6120 | |
| TCGA | OXA1L | 5018 | RNAseq | -0.0676 | 0.1330 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by OXA1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OXA1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OXA1L | 5018 | 9 | 2 | 19 | |
| GSE20123 | OXA1L | 5018 | 9 | 2 | 19 | |
| GSE43470 | OXA1L | 5018 | 7 | 2 | 34 | |
| GSE46452 | OXA1L | 5018 | 17 | 2 | 40 | |
| GSE47630 | OXA1L | 5018 | 11 | 10 | 19 | |
| GSE54993 | OXA1L | 5018 | 3 | 11 | 56 | |
| GSE54994 | OXA1L | 5018 | 18 | 5 | 30 | |
| GSE60625 | OXA1L | 5018 | 0 | 2 | 9 | |
| GSE74703 | OXA1L | 5018 | 6 | 2 | 28 | |
| GSE74704 | OXA1L | 5018 | 4 | 1 | 15 | |
| TCGA | OXA1L | 5018 | 25 | 17 | 54 |
Total number of gains: 109; Total number of losses: 56; Total Number of normals: 323.
Somatic mutations of OXA1L:
Generating mutation plots.
Highly correlated genes for OXA1L:
Showing top 20/285 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OXA1L | RNF145 | 0.763668 | 3 | 0 | 3 |
| OXA1L | ARNT | 0.749142 | 3 | 0 | 3 |
| OXA1L | METTL17 | 0.74575 | 10 | 0 | 9 |
| OXA1L | FLOT2 | 0.742834 | 3 | 0 | 3 |
| OXA1L | SLC16A5 | 0.714625 | 3 | 0 | 3 |
| OXA1L | IL6R | 0.709584 | 3 | 0 | 3 |
| OXA1L | CHURC1 | 0.706063 | 5 | 0 | 4 |
| OXA1L | USP21 | 0.705949 | 4 | 0 | 3 |
| OXA1L | PPP6R2 | 0.703662 | 3 | 0 | 3 |
| OXA1L | ABLIM2 | 0.697182 | 3 | 0 | 3 |
| OXA1L | TOX4 | 0.686882 | 9 | 0 | 6 |
| OXA1L | POLR2K | 0.686015 | 3 | 0 | 3 |
| OXA1L | PRCC | 0.685869 | 4 | 0 | 3 |
| OXA1L | HARS2 | 0.685232 | 4 | 0 | 3 |
| OXA1L | HAUS4 | 0.684856 | 4 | 0 | 4 |
| OXA1L | TRAPPC2L | 0.677826 | 4 | 0 | 3 |
| OXA1L | PNP | 0.676641 | 6 | 0 | 5 |
| OXA1L | MRPL30 | 0.676534 | 4 | 0 | 3 |
| OXA1L | DAD1 | 0.660986 | 10 | 0 | 8 |
| OXA1L | EIF3M | 0.654509 | 4 | 0 | 3 |
For details and further investigation, click here
