| Full name: TOX high mobility group box family member 4 | Alias Symbol: LCP1 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 9878 | HGNC ID: HGNC:20161 | Ensembl Gene: ENSG00000092203 | OMIM ID: 614032 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TOX4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TOX4 | 9878 | 201684_s_at | -0.0609 | 0.9376 | |
| GSE20347 | TOX4 | 9878 | 201684_s_at | -0.0839 | 0.5697 | |
| GSE23400 | TOX4 | 9878 | 201684_s_at | -0.0289 | 0.5822 | |
| GSE26886 | TOX4 | 9878 | 201684_s_at | -0.4286 | 0.0046 | |
| GSE29001 | TOX4 | 9878 | 201684_s_at | -0.3211 | 0.0698 | |
| GSE38129 | TOX4 | 9878 | 201684_s_at | -0.0115 | 0.9315 | |
| GSE45670 | TOX4 | 9878 | 201684_s_at | 0.1659 | 0.1664 | |
| GSE53622 | TOX4 | 9878 | 130721 | -0.4434 | 0.0000 | |
| GSE53624 | TOX4 | 9878 | 130721 | -0.5282 | 0.0000 | |
| GSE63941 | TOX4 | 9878 | 201684_s_at | 1.0519 | 0.0160 | |
| GSE77861 | TOX4 | 9878 | 201684_s_at | 0.2374 | 0.6004 | |
| GSE97050 | TOX4 | 9878 | A_23_P404134 | -0.7345 | 0.1291 | |
| SRP007169 | TOX4 | 9878 | RNAseq | -0.6600 | 0.0783 | |
| SRP008496 | TOX4 | 9878 | RNAseq | -0.9120 | 0.0003 | |
| SRP064894 | TOX4 | 9878 | RNAseq | -0.2369 | 0.0520 | |
| SRP133303 | TOX4 | 9878 | RNAseq | -0.0049 | 0.9841 | |
| SRP159526 | TOX4 | 9878 | RNAseq | -0.3578 | 0.0653 | |
| SRP193095 | TOX4 | 9878 | RNAseq | -0.2456 | 0.0323 | |
| SRP219564 | TOX4 | 9878 | RNAseq | -0.2558 | 0.1612 | |
| TCGA | TOX4 | 9878 | RNAseq | -0.0529 | 0.2375 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TOX4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TOX4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TOX4 | 9878 | 9 | 3 | 18 | |
| GSE20123 | TOX4 | 9878 | 9 | 3 | 18 | |
| GSE43470 | TOX4 | 9878 | 7 | 2 | 34 | |
| GSE46452 | TOX4 | 9878 | 18 | 2 | 39 | |
| GSE47630 | TOX4 | 9878 | 10 | 10 | 20 | |
| GSE54993 | TOX4 | 9878 | 3 | 11 | 56 | |
| GSE54994 | TOX4 | 9878 | 18 | 5 | 30 | |
| GSE60625 | TOX4 | 9878 | 0 | 2 | 9 | |
| GSE74703 | TOX4 | 9878 | 6 | 2 | 28 | |
| GSE74704 | TOX4 | 9878 | 4 | 2 | 14 | |
| TCGA | TOX4 | 9878 | 27 | 16 | 53 |
Total number of gains: 111; Total number of losses: 58; Total Number of normals: 319.
Somatic mutations of TOX4:
Generating mutation plots.
Highly correlated genes for TOX4:
Showing top 20/405 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TOX4 | UBE2E2 | 0.796049 | 3 | 0 | 3 |
| TOX4 | PAQR7 | 0.751226 | 3 | 0 | 3 |
| TOX4 | METTL17 | 0.744569 | 6 | 0 | 6 |
| TOX4 | RAB2B | 0.727934 | 5 | 0 | 5 |
| TOX4 | FBXO33 | 0.718434 | 3 | 0 | 3 |
| TOX4 | CFL2 | 0.715932 | 4 | 0 | 4 |
| TOX4 | SNW1 | 0.712402 | 4 | 0 | 4 |
| TOX4 | SNRNP27 | 0.705279 | 4 | 0 | 3 |
| TOX4 | TCEAL6 | 0.699516 | 3 | 0 | 3 |
| TOX4 | AP4S1 | 0.698153 | 3 | 0 | 3 |
| TOX4 | RAB3GAP2 | 0.697642 | 3 | 0 | 3 |
| TOX4 | EXOC6B | 0.697434 | 4 | 0 | 3 |
| TOX4 | PKN2 | 0.695524 | 3 | 0 | 3 |
| TOX4 | OXA1L | 0.686882 | 9 | 0 | 6 |
| TOX4 | CIRBP | 0.685631 | 5 | 0 | 5 |
| TOX4 | XPA | 0.68463 | 3 | 0 | 3 |
| TOX4 | NFIA | 0.684034 | 4 | 0 | 4 |
| TOX4 | NFKBIZ | 0.683129 | 3 | 0 | 3 |
| TOX4 | HSPA9 | 0.682906 | 4 | 0 | 3 |
| TOX4 | EIF2B4 | 0.681725 | 5 | 0 | 5 |
For details and further investigation, click here
