| Full name: platelet activating factor acetylhydrolase 1b regulatory subunit 1 | Alias Symbol: LIS1|PAFAH|NudF | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 5048 | HGNC ID: HGNC:8574 | Ensembl Gene: ENSG00000007168 | OMIM ID: 601545 |
| Drug and gene relationship at DGIdb | |||
Expression of PAFAH1B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAFAH1B1 | 5048 | 200816_s_at | -0.5009 | 0.1313 | |
| GSE20347 | PAFAH1B1 | 5048 | 200816_s_at | -0.4729 | 0.0009 | |
| GSE23400 | PAFAH1B1 | 5048 | 200816_s_at | -0.0848 | 0.3525 | |
| GSE26886 | PAFAH1B1 | 5048 | 200816_s_at | -0.9872 | 0.0019 | |
| GSE29001 | PAFAH1B1 | 5048 | 200815_s_at | -0.0070 | 0.9797 | |
| GSE38129 | PAFAH1B1 | 5048 | 200816_s_at | -0.4274 | 0.0005 | |
| GSE45670 | PAFAH1B1 | 5048 | 200816_s_at | -0.2227 | 0.0201 | |
| GSE53622 | PAFAH1B1 | 5048 | 102439 | -0.0486 | 0.2753 | |
| GSE53624 | PAFAH1B1 | 5048 | 102439 | 0.1004 | 0.0387 | |
| GSE63941 | PAFAH1B1 | 5048 | 200816_s_at | -1.0201 | 0.0465 | |
| GSE77861 | PAFAH1B1 | 5048 | 200815_s_at | 0.3318 | 0.3130 | |
| GSE97050 | PAFAH1B1 | 5048 | A_23_P118888 | -0.0710 | 0.7538 | |
| SRP007169 | PAFAH1B1 | 5048 | RNAseq | -0.3185 | 0.2660 | |
| SRP008496 | PAFAH1B1 | 5048 | RNAseq | -0.2516 | 0.0457 | |
| SRP064894 | PAFAH1B1 | 5048 | RNAseq | -0.1419 | 0.2469 | |
| SRP133303 | PAFAH1B1 | 5048 | RNAseq | -0.1387 | 0.2183 | |
| SRP159526 | PAFAH1B1 | 5048 | RNAseq | -0.2443 | 0.2039 | |
| SRP193095 | PAFAH1B1 | 5048 | RNAseq | -0.1178 | 0.0924 | |
| SRP219564 | PAFAH1B1 | 5048 | RNAseq | -0.1717 | 0.4362 | |
| TCGA | PAFAH1B1 | 5048 | RNAseq | -0.1013 | 0.0135 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PAFAH1B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAFAH1B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAFAH1B1 | 5048 | 4 | 2 | 24 | |
| GSE20123 | PAFAH1B1 | 5048 | 4 | 3 | 23 | |
| GSE43470 | PAFAH1B1 | 5048 | 1 | 6 | 36 | |
| GSE46452 | PAFAH1B1 | 5048 | 34 | 1 | 24 | |
| GSE47630 | PAFAH1B1 | 5048 | 7 | 1 | 32 | |
| GSE54993 | PAFAH1B1 | 5048 | 4 | 3 | 63 | |
| GSE54994 | PAFAH1B1 | 5048 | 6 | 9 | 38 | |
| GSE60625 | PAFAH1B1 | 5048 | 4 | 0 | 7 | |
| GSE74703 | PAFAH1B1 | 5048 | 1 | 3 | 32 | |
| GSE74704 | PAFAH1B1 | 5048 | 2 | 1 | 17 | |
| TCGA | PAFAH1B1 | 5048 | 17 | 21 | 58 |
Total number of gains: 84; Total number of losses: 50; Total Number of normals: 354.
Somatic mutations of PAFAH1B1:
Generating mutation plots.
Highly correlated genes for PAFAH1B1:
Showing top 20/74 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAFAH1B1 | BCDIN3D | 0.742972 | 3 | 0 | 3 |
| PAFAH1B1 | MFSD1 | 0.730825 | 3 | 0 | 3 |
| PAFAH1B1 | ZKSCAN2 | 0.700842 | 3 | 0 | 3 |
| PAFAH1B1 | CYB5D2 | 0.694113 | 3 | 0 | 3 |
| PAFAH1B1 | ERN1 | 0.693696 | 3 | 0 | 3 |
| PAFAH1B1 | INPP4B | 0.691432 | 3 | 0 | 3 |
| PAFAH1B1 | MOB1B | 0.690382 | 4 | 0 | 4 |
| PAFAH1B1 | ABCD3 | 0.688987 | 4 | 0 | 4 |
| PAFAH1B1 | PDZD2 | 0.683439 | 3 | 0 | 3 |
| PAFAH1B1 | DMGDH | 0.671271 | 4 | 0 | 4 |
| PAFAH1B1 | UCK1 | 0.659652 | 3 | 0 | 3 |
| PAFAH1B1 | LINC00938 | 0.651859 | 3 | 0 | 3 |
| PAFAH1B1 | FAM110B | 0.647259 | 4 | 0 | 3 |
| PAFAH1B1 | SLC6A1 | 0.640782 | 3 | 0 | 3 |
| PAFAH1B1 | PDZRN3 | 0.634961 | 7 | 0 | 5 |
| PAFAH1B1 | SERPINB6 | 0.621633 | 4 | 0 | 4 |
| PAFAH1B1 | NDNF | 0.61805 | 4 | 0 | 3 |
| PAFAH1B1 | ZC3H6 | 0.614861 | 5 | 0 | 3 |
| PAFAH1B1 | STK24 | 0.614416 | 3 | 0 | 3 |
| PAFAH1B1 | RBM43 | 0.61423 | 5 | 0 | 3 |
For details and further investigation, click here
