| Full name: serine/threonine kinase 24 | Alias Symbol: MST-3|MST3|MST3B|STK3|STE20 | ||
| Type: protein-coding gene | Cytoband: 13q32.2 | ||
| Entrez ID: 8428 | HGNC ID: HGNC:11403 | Ensembl Gene: ENSG00000102572 | OMIM ID: 604984 |
| Drug and gene relationship at DGIdb | |||
Expression of STK24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STK24 | 8428 | 208855_s_at | -0.2921 | 0.4792 | |
| GSE20347 | STK24 | 8428 | 208855_s_at | -0.8167 | 0.0000 | |
| GSE23400 | STK24 | 8428 | 208855_s_at | -0.6040 | 0.0000 | |
| GSE26886 | STK24 | 8428 | 208855_s_at | -0.6740 | 0.0000 | |
| GSE29001 | STK24 | 8428 | 208855_s_at | -0.2407 | 0.1119 | |
| GSE38129 | STK24 | 8428 | 208855_s_at | -0.5399 | 0.0028 | |
| GSE45670 | STK24 | 8428 | 208855_s_at | -0.1882 | 0.1511 | |
| GSE53622 | STK24 | 8428 | 56742 | -0.9049 | 0.0000 | |
| GSE53624 | STK24 | 8428 | 56742 | -1.1781 | 0.0000 | |
| GSE63941 | STK24 | 8428 | 208855_s_at | 0.8544 | 0.0134 | |
| GSE77861 | STK24 | 8428 | 208855_s_at | -0.8143 | 0.0005 | |
| GSE97050 | STK24 | 8428 | A_23_P253177 | -0.8370 | 0.2859 | |
| SRP007169 | STK24 | 8428 | RNAseq | -2.6175 | 0.0000 | |
| SRP008496 | STK24 | 8428 | RNAseq | -2.7170 | 0.0000 | |
| SRP064894 | STK24 | 8428 | RNAseq | -1.5416 | 0.0000 | |
| SRP133303 | STK24 | 8428 | RNAseq | -0.8290 | 0.0000 | |
| SRP159526 | STK24 | 8428 | RNAseq | -1.6438 | 0.0006 | |
| SRP193095 | STK24 | 8428 | RNAseq | -1.2523 | 0.0000 | |
| SRP219564 | STK24 | 8428 | RNAseq | -1.3213 | 0.0133 | |
| TCGA | STK24 | 8428 | RNAseq | 0.0176 | 0.7173 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by STK24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STK24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STK24 | 8428 | 3 | 9 | 18 | |
| GSE20123 | STK24 | 8428 | 3 | 9 | 18 | |
| GSE43470 | STK24 | 8428 | 4 | 12 | 27 | |
| GSE46452 | STK24 | 8428 | 0 | 32 | 27 | |
| GSE47630 | STK24 | 8428 | 3 | 26 | 11 | |
| GSE54993 | STK24 | 8428 | 11 | 4 | 55 | |
| GSE54994 | STK24 | 8428 | 3 | 12 | 38 | |
| GSE60625 | STK24 | 8428 | 0 | 3 | 8 | |
| GSE74703 | STK24 | 8428 | 3 | 10 | 23 | |
| GSE74704 | STK24 | 8428 | 1 | 8 | 11 | |
| TCGA | STK24 | 8428 | 13 | 35 | 48 |
Total number of gains: 44; Total number of losses: 160; Total Number of normals: 284.
Somatic mutations of STK24:
Generating mutation plots.
Highly correlated genes for STK24:
Showing top 20/1104 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STK24 | PCBP1-AS1 | 0.78647 | 3 | 0 | 3 |
| STK24 | EPS8L2 | 0.778847 | 11 | 0 | 11 |
| STK24 | C6orf132 | 0.77104 | 8 | 0 | 8 |
| STK24 | HES5 | 0.767326 | 3 | 0 | 3 |
| STK24 | ZNF431 | 0.767104 | 4 | 0 | 4 |
| STK24 | NCCRP1 | 0.766955 | 3 | 0 | 3 |
| STK24 | DOCK9 | 0.762574 | 12 | 0 | 11 |
| STK24 | OTOP3 | 0.75412 | 3 | 0 | 3 |
| STK24 | MMEL1 | 0.750063 | 4 | 0 | 4 |
| STK24 | EPS8L1 | 0.746692 | 11 | 0 | 11 |
| STK24 | RAB25 | 0.739891 | 10 | 0 | 10 |
| STK24 | C1orf116 | 0.739713 | 12 | 0 | 12 |
| STK24 | SH3GL1 | 0.738345 | 11 | 0 | 10 |
| STK24 | FAM163B | 0.736304 | 3 | 0 | 3 |
| STK24 | ACPP | 0.732824 | 11 | 0 | 10 |
| STK24 | ESPL1 | 0.732751 | 11 | 0 | 10 |
| STK24 | EVPL | 0.732523 | 12 | 0 | 11 |
| STK24 | TMEM154 | 0.732201 | 7 | 0 | 7 |
| STK24 | GYS2 | 0.729481 | 10 | 0 | 10 |
| STK24 | SLC44A3 | 0.727021 | 6 | 0 | 6 |
For details and further investigation, click here
