| Full name: interferon alpha 8 | Alias Symbol: IFN-alphaB | ||
| Type: protein-coding gene | Cytoband: 9p21.3 | ||
| Entrez ID: 3445 | HGNC ID: HGNC:5429 | Ensembl Gene: ENSG00000120242 | OMIM ID: 147568 |
| Drug and gene relationship at DGIdb | |||
IFNA8 involved pathways:
Expression of IFNA8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IFNA8 | 3445 | 207932_at | -0.0167 | 0.9599 | |
| GSE20347 | IFNA8 | 3445 | 207932_at | 0.0069 | 0.9046 | |
| GSE23400 | IFNA8 | 3445 | 207932_at | -0.0706 | 0.0000 | |
| GSE26886 | IFNA8 | 3445 | 207932_at | -0.0198 | 0.8369 | |
| GSE29001 | IFNA8 | 3445 | 207932_at | -0.0982 | 0.2743 | |
| GSE38129 | IFNA8 | 3445 | 207932_at | -0.0232 | 0.5709 | |
| GSE45670 | IFNA8 | 3445 | 207932_at | -0.0004 | 0.9971 | |
| GSE53622 | IFNA8 | 3445 | 114501 | 0.0105 | 0.8561 | |
| GSE53624 | IFNA8 | 3445 | 114501 | -0.0064 | 0.9260 | |
| GSE63941 | IFNA8 | 3445 | 207932_at | -0.1396 | 0.3235 | |
| GSE77861 | IFNA8 | 3445 | 207932_at | -0.0484 | 0.4955 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFNA8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFNA8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFNA8 | 3445 | 2 | 17 | 11 | |
| GSE20123 | IFNA8 | 3445 | 2 | 17 | 11 | |
| GSE43470 | IFNA8 | 3445 | 3 | 13 | 27 | |
| GSE46452 | IFNA8 | 3445 | 2 | 24 | 33 | |
| GSE47630 | IFNA8 | 3445 | 3 | 27 | 10 | |
| GSE54993 | IFNA8 | 3445 | 7 | 2 | 61 | |
| GSE54994 | IFNA8 | 3445 | 8 | 17 | 28 | |
| GSE60625 | IFNA8 | 3445 | 3 | 0 | 8 | |
| GSE74703 | IFNA8 | 3445 | 3 | 10 | 23 | |
| GSE74704 | IFNA8 | 3445 | 0 | 13 | 7 | |
| TCGA | IFNA8 | 3445 | 11 | 53 | 32 |
Total number of gains: 44; Total number of losses: 193; Total Number of normals: 251.
Somatic mutations of IFNA8:
Generating mutation plots.
Highly correlated genes for IFNA8:
Showing top 20/94 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFNA8 | FLT3 | 0.686918 | 3 | 0 | 3 |
| IFNA8 | TAAR2 | 0.685997 | 3 | 0 | 3 |
| IFNA8 | PSG9 | 0.682903 | 3 | 0 | 3 |
| IFNA8 | GCG | 0.667388 | 3 | 0 | 3 |
| IFNA8 | PKLR | 0.653832 | 3 | 0 | 3 |
| IFNA8 | PAPOLB | 0.647018 | 3 | 0 | 3 |
| IFNA8 | CD244 | 0.645472 | 4 | 0 | 3 |
| IFNA8 | NPC1L1 | 0.642972 | 3 | 0 | 3 |
| IFNA8 | GBX2 | 0.641629 | 3 | 0 | 3 |
| IFNA8 | FOXN1 | 0.627765 | 3 | 0 | 3 |
| IFNA8 | CDH17 | 0.623234 | 3 | 0 | 3 |
| IFNA8 | RAPGEF3 | 0.622578 | 3 | 0 | 3 |
| IFNA8 | THRB | 0.621948 | 3 | 0 | 3 |
| IFNA8 | LZTS1 | 0.618075 | 4 | 0 | 3 |
| IFNA8 | LINC00474 | 0.612328 | 3 | 0 | 3 |
| IFNA8 | PRTN3 | 0.607016 | 3 | 0 | 3 |
| IFNA8 | AP4S1 | 0.600646 | 4 | 0 | 4 |
| IFNA8 | TRPC7 | 0.594941 | 4 | 0 | 4 |
| IFNA8 | THPO | 0.592734 | 4 | 0 | 3 |
| IFNA8 | DENND6B | 0.592652 | 3 | 0 | 3 |
For details and further investigation, click here
