| Full name: mannosyl-oligosaccharide glucosidase | Alias Symbol: GCS1|CWH41|DER7 | ||
| Type: protein-coding gene | Cytoband: 2p13.1 | ||
| Entrez ID: 7841 | HGNC ID: HGNC:24862 | Ensembl Gene: ENSG00000115275 | OMIM ID: 601336 |
| Drug and gene relationship at DGIdb | |||
Expression of MOGS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOGS | 7841 | 210627_s_at | 0.6464 | 0.0702 | |
| GSE20347 | MOGS | 7841 | 210627_s_at | 0.5420 | 0.0024 | |
| GSE23400 | MOGS | 7841 | 210627_s_at | 0.4461 | 0.0000 | |
| GSE26886 | MOGS | 7841 | 210627_s_at | 0.5691 | 0.0149 | |
| GSE29001 | MOGS | 7841 | 210627_s_at | 0.6577 | 0.0223 | |
| GSE38129 | MOGS | 7841 | 210627_s_at | 0.7496 | 0.0000 | |
| GSE45670 | MOGS | 7841 | 210627_s_at | 0.5919 | 0.0007 | |
| GSE53622 | MOGS | 7841 | 88165 | 0.8665 | 0.0000 | |
| GSE53624 | MOGS | 7841 | 88165 | 0.6947 | 0.0000 | |
| GSE63941 | MOGS | 7841 | 210627_s_at | 0.6066 | 0.1361 | |
| GSE77861 | MOGS | 7841 | 210627_s_at | 0.4955 | 0.0108 | |
| GSE97050 | MOGS | 7841 | A_23_P108662 | 0.4494 | 0.1453 | |
| SRP007169 | MOGS | 7841 | RNAseq | 2.2630 | 0.0000 | |
| SRP008496 | MOGS | 7841 | RNAseq | 2.1803 | 0.0000 | |
| SRP064894 | MOGS | 7841 | RNAseq | 0.5823 | 0.0000 | |
| SRP133303 | MOGS | 7841 | RNAseq | 0.5420 | 0.0005 | |
| SRP159526 | MOGS | 7841 | RNAseq | 1.1220 | 0.0000 | |
| SRP193095 | MOGS | 7841 | RNAseq | 0.3843 | 0.0037 | |
| SRP219564 | MOGS | 7841 | RNAseq | 0.6283 | 0.1086 | |
| TCGA | MOGS | 7841 | RNAseq | 0.1096 | 0.0257 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by MOGS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MOGS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOGS | 7841 | 9 | 2 | 19 | |
| GSE20123 | MOGS | 7841 | 10 | 2 | 18 | |
| GSE43470 | MOGS | 7841 | 4 | 0 | 39 | |
| GSE46452 | MOGS | 7841 | 2 | 3 | 54 | |
| GSE47630 | MOGS | 7841 | 7 | 0 | 33 | |
| GSE54993 | MOGS | 7841 | 0 | 6 | 64 | |
| GSE54994 | MOGS | 7841 | 10 | 0 | 43 | |
| GSE60625 | MOGS | 7841 | 0 | 3 | 8 | |
| GSE74703 | MOGS | 7841 | 4 | 0 | 32 | |
| GSE74704 | MOGS | 7841 | 8 | 0 | 12 | |
| TCGA | MOGS | 7841 | 37 | 2 | 57 |
Total number of gains: 91; Total number of losses: 18; Total Number of normals: 379.
Somatic mutations of MOGS:
Generating mutation plots.
Highly correlated genes for MOGS:
Showing top 20/2093 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOGS | CDCA2 | 0.798042 | 4 | 0 | 4 |
| MOGS | GSR | 0.783643 | 3 | 0 | 3 |
| MOGS | ZBTB9 | 0.778141 | 4 | 0 | 4 |
| MOGS | SLC26A6 | 0.777819 | 3 | 0 | 3 |
| MOGS | KRTCAP2 | 0.773903 | 4 | 0 | 4 |
| MOGS | RTKN | 0.761066 | 8 | 0 | 8 |
| MOGS | MTHFD2 | 0.753728 | 10 | 0 | 10 |
| MOGS | BRAT1 | 0.75163 | 7 | 0 | 7 |
| MOGS | PDIA4 | 0.742887 | 10 | 0 | 10 |
| MOGS | DOCK6 | 0.741072 | 4 | 0 | 4 |
| MOGS | SSH2 | 0.738015 | 3 | 0 | 3 |
| MOGS | PAPOLG | 0.73504 | 5 | 0 | 5 |
| MOGS | PHC2 | 0.734406 | 4 | 0 | 4 |
| MOGS | GORAB | 0.733545 | 7 | 0 | 7 |
| MOGS | CDCA3 | 0.731143 | 11 | 0 | 10 |
| MOGS | FKTN | 0.726424 | 3 | 0 | 3 |
| MOGS | ORAI1 | 0.724962 | 6 | 0 | 5 |
| MOGS | BMP2 | 0.72447 | 3 | 0 | 3 |
| MOGS | DGUOK | 0.723886 | 12 | 0 | 10 |
| MOGS | PHF5A | 0.718741 | 6 | 0 | 6 |
For details and further investigation, click here
