| Full name: paired box 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20p11.22 | ||
| Entrez ID: 5075 | HGNC ID: HGNC:8615 | Ensembl Gene: ENSG00000125813 | OMIM ID: 167411 |
| Drug and gene relationship at DGIdb | |||
Expression of PAX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAX1 | 5075 | 214401_at | -0.6000 | 0.4038 | |
| GSE20347 | PAX1 | 5075 | 214401_at | -0.5097 | 0.0015 | |
| GSE23400 | PAX1 | 5075 | 214401_at | -0.2490 | 0.0000 | |
| GSE26886 | PAX1 | 5075 | 1553492_a_at | -0.0892 | 0.5891 | |
| GSE29001 | PAX1 | 5075 | 214401_at | -0.3437 | 0.0938 | |
| GSE38129 | PAX1 | 5075 | 214401_at | -0.5781 | 0.0001 | |
| GSE45670 | PAX1 | 5075 | 231445_at | 0.0023 | 0.9893 | |
| GSE53622 | PAX1 | 5075 | 65916 | -2.7822 | 0.0000 | |
| GSE53624 | PAX1 | 5075 | 65916 | -3.1132 | 0.0000 | |
| GSE63941 | PAX1 | 5075 | 214401_at | -0.0723 | 0.7439 | |
| GSE77861 | PAX1 | 5075 | 214401_at | -0.1915 | 0.1604 | |
| SRP133303 | PAX1 | 5075 | RNAseq | -2.7524 | 0.0000 | |
| TCGA | PAX1 | 5075 | RNAseq | 1.9639 | 0.0347 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by PAX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAX1 | 5075 | 13 | 1 | 16 | |
| GSE20123 | PAX1 | 5075 | 13 | 1 | 16 | |
| GSE43470 | PAX1 | 5075 | 11 | 1 | 31 | |
| GSE46452 | PAX1 | 5075 | 27 | 1 | 31 | |
| GSE47630 | PAX1 | 5075 | 17 | 4 | 19 | |
| GSE54993 | PAX1 | 5075 | 0 | 16 | 54 | |
| GSE54994 | PAX1 | 5075 | 27 | 2 | 24 | |
| GSE60625 | PAX1 | 5075 | 0 | 0 | 11 | |
| GSE74703 | PAX1 | 5075 | 8 | 1 | 27 | |
| GSE74704 | PAX1 | 5075 | 7 | 1 | 12 | |
| TCGA | PAX1 | 5075 | 44 | 10 | 42 |
Total number of gains: 167; Total number of losses: 38; Total Number of normals: 283.
Somatic mutations of PAX1:
Generating mutation plots.
Highly correlated genes for PAX1:
Showing top 20/642 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAX1 | CCDC160 | 0.701635 | 3 | 0 | 3 |
| PAX1 | KRT78 | 0.681232 | 4 | 0 | 4 |
| PAX1 | MORN3 | 0.673413 | 3 | 0 | 3 |
| PAX1 | FAM3D | 0.672775 | 4 | 0 | 4 |
| PAX1 | VSIG2 | 0.672765 | 4 | 0 | 4 |
| PAX1 | PLEKHN1 | 0.66636 | 4 | 0 | 4 |
| PAX1 | CRTAC1 | 0.65757 | 9 | 0 | 8 |
| PAX1 | IQCF1 | 0.647976 | 4 | 0 | 4 |
| PAX1 | ATG9B | 0.644314 | 4 | 0 | 4 |
| PAX1 | HCG9 | 0.644186 | 3 | 0 | 3 |
| PAX1 | MAPK3 | 0.643824 | 8 | 0 | 8 |
| PAX1 | TFAP2B | 0.642797 | 7 | 0 | 7 |
| PAX1 | DEGS2 | 0.640997 | 4 | 0 | 4 |
| PAX1 | LNX1 | 0.639009 | 4 | 0 | 4 |
| PAX1 | HCG22 | 0.636558 | 4 | 0 | 4 |
| PAX1 | HS3ST6 | 0.635743 | 4 | 0 | 4 |
| PAX1 | TMEM141 | 0.632783 | 3 | 0 | 3 |
| PAX1 | ATP13A4 | 0.632465 | 4 | 0 | 4 |
| PAX1 | ZNF431 | 0.631999 | 3 | 0 | 3 |
| PAX1 | C15orf62 | 0.630096 | 4 | 0 | 4 |
For details and further investigation, click here
