| Full name: PDX1 C-terminal inhibiting factor 1 | Alias Symbol: bA465L10.1|PPP1R121 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 63935 | HGNC ID: HGNC:16200 | Ensembl Gene: ENSG00000100982 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PCIF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCIF1 | 63935 | 221762_s_at | 0.2977 | 0.1787 | |
| GSE20347 | PCIF1 | 63935 | 221762_s_at | 0.0532 | 0.6828 | |
| GSE23400 | PCIF1 | 63935 | 221762_s_at | 0.0079 | 0.8666 | |
| GSE26886 | PCIF1 | 63935 | 89948_at | 0.5662 | 0.0000 | |
| GSE29001 | PCIF1 | 63935 | 221762_s_at | -0.0108 | 0.9780 | |
| GSE38129 | PCIF1 | 63935 | 221762_s_at | 0.0292 | 0.7957 | |
| GSE45670 | PCIF1 | 63935 | 89948_at | -0.0717 | 0.4844 | |
| GSE53622 | PCIF1 | 63935 | 109301 | 0.0346 | 0.5344 | |
| GSE53624 | PCIF1 | 63935 | 109301 | -0.1850 | 0.0207 | |
| GSE63941 | PCIF1 | 63935 | 89948_at | 0.3064 | 0.3282 | |
| GSE77861 | PCIF1 | 63935 | 89948_at | 0.0022 | 0.9867 | |
| GSE97050 | PCIF1 | 63935 | A_23_P210496 | -0.1155 | 0.5659 | |
| SRP007169 | PCIF1 | 63935 | RNAseq | -0.3815 | 0.2267 | |
| SRP008496 | PCIF1 | 63935 | RNAseq | -0.0793 | 0.7154 | |
| SRP064894 | PCIF1 | 63935 | RNAseq | 0.2340 | 0.1300 | |
| SRP133303 | PCIF1 | 63935 | RNAseq | -0.0641 | 0.6266 | |
| SRP159526 | PCIF1 | 63935 | RNAseq | 0.2870 | 0.4317 | |
| SRP193095 | PCIF1 | 63935 | RNAseq | 0.1330 | 0.2395 | |
| SRP219564 | PCIF1 | 63935 | RNAseq | 0.1750 | 0.4411 | |
| TCGA | PCIF1 | 63935 | RNAseq | 0.0571 | 0.2184 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PCIF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCIF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCIF1 | 63935 | 14 | 1 | 15 | |
| GSE20123 | PCIF1 | 63935 | 14 | 1 | 15 | |
| GSE43470 | PCIF1 | 63935 | 12 | 1 | 30 | |
| GSE46452 | PCIF1 | 63935 | 29 | 0 | 30 | |
| GSE47630 | PCIF1 | 63935 | 24 | 1 | 15 | |
| GSE54993 | PCIF1 | 63935 | 0 | 17 | 53 | |
| GSE54994 | PCIF1 | 63935 | 25 | 0 | 28 | |
| GSE60625 | PCIF1 | 63935 | 0 | 0 | 11 | |
| GSE74703 | PCIF1 | 63935 | 10 | 1 | 25 | |
| GSE74704 | PCIF1 | 63935 | 10 | 0 | 10 | |
| TCGA | PCIF1 | 63935 | 46 | 3 | 47 |
Total number of gains: 184; Total number of losses: 25; Total Number of normals: 279.
Somatic mutations of PCIF1:
Generating mutation plots.
Highly correlated genes for PCIF1:
Showing top 20/138 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCIF1 | SLC12A9 | 0.728196 | 3 | 0 | 3 |
| PCIF1 | MYBL2 | 0.722821 | 3 | 0 | 3 |
| PCIF1 | SYN2 | 0.721372 | 3 | 0 | 3 |
| PCIF1 | POP7 | 0.719655 | 3 | 0 | 3 |
| PCIF1 | GPC2 | 0.71947 | 3 | 0 | 3 |
| PCIF1 | RNA45S5 | 0.71093 | 3 | 0 | 3 |
| PCIF1 | C6orf223 | 0.709755 | 3 | 0 | 3 |
| PCIF1 | PRKCSH | 0.706914 | 4 | 0 | 3 |
| PCIF1 | GAS6-AS1 | 0.698284 | 3 | 0 | 3 |
| PCIF1 | KHSRP | 0.697566 | 4 | 0 | 4 |
| PCIF1 | ZNF524 | 0.69223 | 3 | 0 | 3 |
| PCIF1 | DNM2 | 0.674126 | 3 | 0 | 3 |
| PCIF1 | NACAD | 0.667211 | 3 | 0 | 3 |
| PCIF1 | HTRA3 | 0.666383 | 3 | 0 | 3 |
| PCIF1 | PAM16 | 0.664195 | 3 | 0 | 3 |
| PCIF1 | RAD23A | 0.663048 | 4 | 0 | 4 |
| PCIF1 | KLC2 | 0.656176 | 3 | 0 | 3 |
| PCIF1 | SBK1 | 0.65546 | 3 | 0 | 3 |
| PCIF1 | SETD1A | 0.652777 | 3 | 0 | 3 |
| PCIF1 | C10orf55 | 0.64524 | 3 | 0 | 3 |
For details and further investigation, click here
