| Full name: synapsin II | Alias Symbol: SYNII|SYNIIa|SYNIIb | ||
| Type: protein-coding gene | Cytoband: 3p25.2 | ||
| Entrez ID: 6854 | HGNC ID: HGNC:11495 | Ensembl Gene: ENSG00000157152 | OMIM ID: 600755 |
| Drug and gene relationship at DGIdb | |||
Expression of SYN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYN2 | 6854 | 210247_at | 0.2990 | 0.6397 | |
| GSE20347 | SYN2 | 6854 | 210247_at | 0.1837 | 0.0879 | |
| GSE23400 | SYN2 | 6854 | 210247_at | -0.0447 | 0.2855 | |
| GSE26886 | SYN2 | 6854 | 229039_at | 0.4402 | 0.0067 | |
| GSE29001 | SYN2 | 6854 | 210247_at | 0.0417 | 0.8689 | |
| GSE38129 | SYN2 | 6854 | 210247_at | 0.0403 | 0.7870 | |
| GSE45670 | SYN2 | 6854 | 210247_at | 0.1357 | 0.3900 | |
| GSE53622 | SYN2 | 6854 | 120608 | -0.3814 | 0.0593 | |
| GSE53624 | SYN2 | 6854 | 120608 | -0.0324 | 0.9047 | |
| GSE63941 | SYN2 | 6854 | 229039_at | 0.5137 | 0.1607 | |
| GSE77861 | SYN2 | 6854 | 229039_at | -0.0309 | 0.7874 | |
| GSE97050 | SYN2 | 6854 | A_33_P3317613 | -0.1677 | 0.4794 | |
| SRP133303 | SYN2 | 6854 | RNAseq | -0.6164 | 0.2125 | |
| SRP159526 | SYN2 | 6854 | RNAseq | 2.4357 | 0.0006 | |
| TCGA | SYN2 | 6854 | RNAseq | -1.5063 | 0.0070 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by SYN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYN2 | 6854 | 1 | 17 | 12 | |
| GSE20123 | SYN2 | 6854 | 1 | 18 | 11 | |
| GSE43470 | SYN2 | 6854 | 1 | 20 | 22 | |
| GSE46452 | SYN2 | 6854 | 2 | 17 | 40 | |
| GSE47630 | SYN2 | 6854 | 2 | 23 | 15 | |
| GSE54993 | SYN2 | 6854 | 6 | 1 | 63 | |
| GSE54994 | SYN2 | 6854 | 1 | 33 | 19 | |
| GSE60625 | SYN2 | 6854 | 5 | 0 | 6 | |
| GSE74703 | SYN2 | 6854 | 0 | 17 | 19 | |
| GSE74704 | SYN2 | 6854 | 1 | 10 | 9 | |
| TCGA | SYN2 | 6854 | 1 | 68 | 27 |
Total number of gains: 21; Total number of losses: 224; Total Number of normals: 243.
Somatic mutations of SYN2:
Generating mutation plots.
Highly correlated genes for SYN2:
Showing top 20/187 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYN2 | PCIF1 | 0.721372 | 3 | 0 | 3 |
| SYN2 | DMAP1 | 0.689837 | 3 | 0 | 3 |
| SYN2 | KLHL24 | 0.686466 | 3 | 0 | 3 |
| SYN2 | UBE2O | 0.671346 | 3 | 0 | 3 |
| SYN2 | FOXP4 | 0.669318 | 3 | 0 | 3 |
| SYN2 | LNP1 | 0.664823 | 4 | 0 | 4 |
| SYN2 | LRRC47 | 0.661959 | 3 | 0 | 3 |
| SYN2 | NOL4 | 0.646006 | 3 | 0 | 3 |
| SYN2 | ESX1 | 0.644528 | 3 | 0 | 3 |
| SYN2 | C1orf50 | 0.633165 | 3 | 0 | 3 |
| SYN2 | HMCN1 | 0.628871 | 3 | 0 | 3 |
| SYN2 | LRP3 | 0.617578 | 7 | 0 | 6 |
| SYN2 | LINC01410 | 0.617046 | 3 | 0 | 3 |
| SYN2 | TMSB15B | 0.616924 | 3 | 0 | 3 |
| SYN2 | HMX2 | 0.610472 | 3 | 0 | 3 |
| SYN2 | TBPL1 | 0.609841 | 4 | 0 | 3 |
| SYN2 | ELOVL2 | 0.609277 | 6 | 0 | 6 |
| SYN2 | ARAF | 0.608094 | 4 | 0 | 3 |
| SYN2 | TBCC | 0.603897 | 3 | 0 | 3 |
| SYN2 | FGF11 | 0.603212 | 3 | 0 | 3 |
For details and further investigation, click here
