| Full name: Sad1 and UNC84 domain containing 1 | Alias Symbol: KIAA0810|FLJ12407 | ||
| Type: protein-coding gene | Cytoband: 7p22.3 | ||
| Entrez ID: 23353 | HGNC ID: HGNC:18587 | Ensembl Gene: ENSG00000164828 | OMIM ID: 607723 |
| Drug and gene relationship at DGIdb | |||
Expression of SUN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SUN1 | 23353 | 212074_at | -0.0874 | 0.7954 | |
| GSE20347 | SUN1 | 23353 | 212074_at | 0.2460 | 0.0456 | |
| GSE23400 | SUN1 | 23353 | 212074_at | 0.1066 | 0.2630 | |
| GSE26886 | SUN1 | 23353 | 212074_at | 0.2250 | 0.3692 | |
| GSE29001 | SUN1 | 23353 | 212074_at | 0.1120 | 0.5399 | |
| GSE38129 | SUN1 | 23353 | 212074_at | 0.2097 | 0.0339 | |
| GSE45670 | SUN1 | 23353 | 212074_at | -0.1849 | 0.1441 | |
| GSE53622 | SUN1 | 23353 | 70721 | 0.0239 | 0.7688 | |
| GSE53624 | SUN1 | 23353 | 70721 | 0.1697 | 0.0141 | |
| GSE63941 | SUN1 | 23353 | 212074_at | 0.5189 | 0.2507 | |
| GSE77861 | SUN1 | 23353 | 212074_at | 0.3264 | 0.1205 | |
| GSE97050 | SUN1 | 23353 | A_33_P3369663 | -0.2104 | 0.6268 | |
| SRP007169 | SUN1 | 23353 | RNAseq | 0.4218 | 0.3071 | |
| SRP008496 | SUN1 | 23353 | RNAseq | 0.8843 | 0.0075 | |
| SRP064894 | SUN1 | 23353 | RNAseq | -0.1898 | 0.3286 | |
| SRP133303 | SUN1 | 23353 | RNAseq | 0.0346 | 0.8207 | |
| SRP159526 | SUN1 | 23353 | RNAseq | -0.0083 | 0.9706 | |
| SRP193095 | SUN1 | 23353 | RNAseq | 0.0084 | 0.9502 | |
| SRP219564 | SUN1 | 23353 | RNAseq | -0.4062 | 0.1564 | |
| TCGA | SUN1 | 23353 | RNAseq | -0.0037 | 0.9295 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SUN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SUN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SUN1 | 23353 | 14 | 0 | 16 | |
| GSE20123 | SUN1 | 23353 | 14 | 0 | 16 | |
| GSE43470 | SUN1 | 23353 | 6 | 2 | 35 | |
| GSE46452 | SUN1 | 23353 | 13 | 1 | 45 | |
| GSE47630 | SUN1 | 23353 | 12 | 1 | 27 | |
| GSE54993 | SUN1 | 23353 | 3 | 10 | 57 | |
| GSE54994 | SUN1 | 23353 | 20 | 3 | 30 | |
| GSE60625 | SUN1 | 23353 | 0 | 0 | 11 | |
| GSE74703 | SUN1 | 23353 | 6 | 1 | 29 | |
| GSE74704 | SUN1 | 23353 | 9 | 0 | 11 | |
| TCGA | SUN1 | 23353 | 56 | 6 | 34 |
Total number of gains: 153; Total number of losses: 24; Total Number of normals: 311.
Somatic mutations of SUN1:
Generating mutation plots.
Highly correlated genes for SUN1:
Showing top 20/224 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SUN1 | GNA11 | 0.779616 | 3 | 0 | 3 |
| SUN1 | ZNF655 | 0.774924 | 3 | 0 | 3 |
| SUN1 | PCMTD2 | 0.750703 | 3 | 0 | 3 |
| SUN1 | CBFA2T2 | 0.748956 | 3 | 0 | 3 |
| SUN1 | TBPL1 | 0.740287 | 3 | 0 | 3 |
| SUN1 | UBR3 | 0.729808 | 3 | 0 | 3 |
| SUN1 | ZNF451 | 0.727414 | 3 | 0 | 3 |
| SUN1 | ARL5B | 0.713948 | 3 | 0 | 3 |
| SUN1 | HEXA | 0.709797 | 3 | 0 | 3 |
| SUN1 | ZNF121 | 0.709311 | 3 | 0 | 3 |
| SUN1 | USP14 | 0.708538 | 3 | 0 | 3 |
| SUN1 | DSTYK | 0.706227 | 3 | 0 | 3 |
| SUN1 | TSC22D2 | 0.701369 | 3 | 0 | 3 |
| SUN1 | SF1 | 0.699802 | 3 | 0 | 3 |
| SUN1 | ANAPC13 | 0.699787 | 3 | 0 | 3 |
| SUN1 | THOC1 | 0.695586 | 4 | 0 | 3 |
| SUN1 | COPS8 | 0.694807 | 3 | 0 | 3 |
| SUN1 | DIS3L | 0.689226 | 3 | 0 | 3 |
| SUN1 | TNRC6A | 0.687513 | 3 | 0 | 3 |
| SUN1 | KPNA4 | 0.6863 | 3 | 0 | 3 |
For details and further investigation, click here
