| Full name: INTS3 and NABP interacting protein | Alias Symbol: HSPC043|hSSBIP1|SOSS-C|MISE | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 58493 | HGNC ID: HGNC:24994 | Ensembl Gene: ENSG00000148153 | OMIM ID: 613273 |
| Drug and gene relationship at DGIdb | |||
Expression of INIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INIP | 58493 | 223559_s_at | 0.1252 | 0.7449 | |
| GSE26886 | INIP | 58493 | 223559_s_at | -0.0902 | 0.7139 | |
| GSE45670 | INIP | 58493 | 223559_s_at | 0.1921 | 0.0882 | |
| GSE53622 | INIP | 58493 | 52073 | 0.2452 | 0.0002 | |
| GSE53624 | INIP | 58493 | 45119 | 0.2520 | 0.0026 | |
| GSE63941 | INIP | 58493 | 223559_s_at | 1.2525 | 0.0078 | |
| GSE77861 | INIP | 58493 | 223559_s_at | 0.3481 | 0.1323 | |
| SRP007169 | INIP | 58493 | RNAseq | 0.3717 | 0.4285 | |
| SRP008496 | INIP | 58493 | RNAseq | 0.4181 | 0.1045 | |
| SRP064894 | INIP | 58493 | RNAseq | 0.3603 | 0.0158 | |
| SRP133303 | INIP | 58493 | RNAseq | 0.2341 | 0.0463 | |
| SRP159526 | INIP | 58493 | RNAseq | 0.1619 | 0.4394 | |
| SRP193095 | INIP | 58493 | RNAseq | -0.1038 | 0.1726 | |
| SRP219564 | INIP | 58493 | RNAseq | -0.0449 | 0.8836 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by INIP expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of INIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INIP | 58493 | 5 | 10 | 15 | |
| GSE20123 | INIP | 58493 | 5 | 10 | 15 | |
| GSE43470 | INIP | 58493 | 4 | 3 | 36 | |
| GSE46452 | INIP | 58493 | 6 | 13 | 40 | |
| GSE47630 | INIP | 58493 | 3 | 16 | 21 | |
| GSE54993 | INIP | 58493 | 3 | 3 | 64 | |
| GSE54994 | INIP | 58493 | 9 | 10 | 34 | |
| GSE60625 | INIP | 58493 | 0 | 0 | 11 | |
| GSE74703 | INIP | 58493 | 4 | 3 | 29 | |
| GSE74704 | INIP | 58493 | 2 | 8 | 10 | |
| TCGA | INIP | 58493 | 26 | 22 | 48 |
Total number of gains: 67; Total number of losses: 98; Total Number of normals: 323.
Somatic mutations of INIP:
Generating mutation plots.
Highly correlated genes for INIP:
Showing top 20/117 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INIP | CLP1 | 0.647527 | 4 | 0 | 4 |
| INIP | PMPCA | 0.643417 | 3 | 0 | 3 |
| INIP | SLC31A1 | 0.637838 | 3 | 0 | 3 |
| INIP | RPAP3 | 0.632569 | 4 | 0 | 3 |
| INIP | FASTKD2 | 0.628401 | 4 | 0 | 4 |
| INIP | MIRLET7D | 0.6205 | 3 | 0 | 3 |
| INIP | POLE3 | 0.619962 | 7 | 0 | 5 |
| INIP | GLE1 | 0.617213 | 5 | 0 | 4 |
| INIP | BTF3L4 | 0.615747 | 3 | 0 | 3 |
| INIP | PTRH1 | 0.615617 | 3 | 0 | 3 |
| INIP | PRPS2 | 0.614542 | 3 | 0 | 3 |
| INIP | SDHAF2 | 0.612262 | 4 | 0 | 3 |
| INIP | RBM18 | 0.61162 | 4 | 0 | 4 |
| INIP | WDR46 | 0.611496 | 3 | 0 | 3 |
| INIP | TTF1 | 0.609184 | 5 | 0 | 4 |
| INIP | REL | 0.607309 | 3 | 0 | 3 |
| INIP | TMEM69 | 0.605123 | 4 | 0 | 3 |
| INIP | CENPL | 0.603292 | 5 | 0 | 4 |
| INIP | PSMD1 | 0.602418 | 3 | 0 | 3 |
| INIP | PRMT3 | 0.601965 | 4 | 0 | 4 |
For details and further investigation, click here
