| Full name: platelet derived growth factor D | Alias Symbol: SCDGF-B|MSTP036|IEGF | ||
| Type: protein-coding gene | Cytoband: 11q22.3 | ||
| Entrez ID: 80310 | HGNC ID: HGNC:30620 | Ensembl Gene: ENSG00000170962 | OMIM ID: 609673 |
| Drug and gene relationship at DGIdb | |||
PDGFD involved pathways:
Expression of PDGFD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDGFD | 80310 | 219304_s_at | -0.5225 | 0.6702 | |
| GSE20347 | PDGFD | 80310 | 219304_s_at | 0.1520 | 0.6513 | |
| GSE23400 | PDGFD | 80310 | 219304_s_at | -0.2359 | 0.0040 | |
| GSE26886 | PDGFD | 80310 | 222860_s_at | 0.0867 | 0.4101 | |
| GSE29001 | PDGFD | 80310 | 219304_s_at | -0.4066 | 0.0994 | |
| GSE38129 | PDGFD | 80310 | 219304_s_at | -0.5183 | 0.2362 | |
| GSE45670 | PDGFD | 80310 | 219304_s_at | -1.3496 | 0.0000 | |
| GSE53622 | PDGFD | 80310 | 64747 | -0.2325 | 0.2601 | |
| GSE53624 | PDGFD | 80310 | 64747 | -0.3255 | 0.1185 | |
| GSE63941 | PDGFD | 80310 | 219304_s_at | -5.5574 | 0.0002 | |
| GSE77861 | PDGFD | 80310 | 222860_s_at | -0.1544 | 0.1898 | |
| GSE97050 | PDGFD | 80310 | A_24_P124349 | -0.0717 | 0.9310 | |
| SRP007169 | PDGFD | 80310 | RNAseq | 1.4299 | 0.0164 | |
| SRP064894 | PDGFD | 80310 | RNAseq | 0.3551 | 0.3113 | |
| SRP133303 | PDGFD | 80310 | RNAseq | 0.0894 | 0.6533 | |
| SRP159526 | PDGFD | 80310 | RNAseq | -0.1367 | 0.7830 | |
| SRP193095 | PDGFD | 80310 | RNAseq | -1.1044 | 0.0110 | |
| SRP219564 | PDGFD | 80310 | RNAseq | 0.5990 | 0.4136 | |
| TCGA | PDGFD | 80310 | RNAseq | -1.2339 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by PDGFD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDGFD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PDGFD | 80310 | 2 | 10 | 18 | |
| GSE20123 | PDGFD | 80310 | 2 | 10 | 18 | |
| GSE43470 | PDGFD | 80310 | 3 | 6 | 34 | |
| GSE46452 | PDGFD | 80310 | 3 | 26 | 30 | |
| GSE47630 | PDGFD | 80310 | 2 | 19 | 19 | |
| GSE54993 | PDGFD | 80310 | 9 | 1 | 60 | |
| GSE54994 | PDGFD | 80310 | 4 | 19 | 30 | |
| GSE60625 | PDGFD | 80310 | 0 | 3 | 8 | |
| GSE74703 | PDGFD | 80310 | 2 | 4 | 30 | |
| GSE74704 | PDGFD | 80310 | 2 | 6 | 12 | |
| TCGA | PDGFD | 80310 | 10 | 44 | 42 |
Total number of gains: 39; Total number of losses: 148; Total Number of normals: 301.
Somatic mutations of PDGFD:
Generating mutation plots.
Highly correlated genes for PDGFD:
Showing top 20/1112 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDGFD | AFF3 | 0.808298 | 3 | 0 | 3 |
| PDGFD | INMT | 0.780565 | 4 | 0 | 4 |
| PDGFD | ZNF578 | 0.749748 | 3 | 0 | 3 |
| PDGFD | TMOD1 | 0.74327 | 5 | 0 | 5 |
| PDGFD | CD99L2 | 0.740846 | 4 | 0 | 4 |
| PDGFD | NAP1L3 | 0.739847 | 7 | 0 | 7 |
| PDGFD | PABPC5 | 0.731496 | 5 | 0 | 5 |
| PDGFD | ZNF25 | 0.728886 | 6 | 0 | 5 |
| PDGFD | TBX5-AS1 | 0.727915 | 4 | 0 | 4 |
| PDGFD | LAMA2 | 0.724146 | 7 | 0 | 6 |
| PDGFD | CLIP3 | 0.721167 | 8 | 0 | 8 |
| PDGFD | PBXIP1 | 0.71711 | 7 | 0 | 7 |
| PDGFD | FRZB | 0.717023 | 7 | 0 | 7 |
| PDGFD | TSPAN18 | 0.716916 | 3 | 0 | 3 |
| PDGFD | PDE1A | 0.714101 | 9 | 0 | 9 |
| PDGFD | WWTR1 | 0.711803 | 4 | 0 | 3 |
| PDGFD | STARD9 | 0.711325 | 4 | 0 | 4 |
| PDGFD | SPOCK1 | 0.707504 | 4 | 0 | 3 |
| PDGFD | CNRIP1 | 0.70639 | 7 | 0 | 6 |
| PDGFD | TMEM178A | 0.706247 | 3 | 0 | 3 |
For details and further investigation, click here
