| Full name: CDK5 regulatory subunit associated protein 1 | Alias Symbol: CGI-05|HSPC167|C42 | ||
| Type: protein-coding gene | Cytoband: 20q11.21 | ||
| Entrez ID: 51654 | HGNC ID: HGNC:15880 | Ensembl Gene: ENSG00000101391 | OMIM ID: 608200 |
| Drug and gene relationship at DGIdb | |||
Expression of CDK5RAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDK5RAP1 | 51654 | 218315_s_at | 0.6025 | 0.1928 | |
| GSE20347 | CDK5RAP1 | 51654 | 218315_s_at | 0.4736 | 0.0001 | |
| GSE23400 | CDK5RAP1 | 51654 | 218315_s_at | 0.2843 | 0.0000 | |
| GSE26886 | CDK5RAP1 | 51654 | 218315_s_at | 0.7462 | 0.0003 | |
| GSE29001 | CDK5RAP1 | 51654 | 218315_s_at | 0.7201 | 0.0045 | |
| GSE38129 | CDK5RAP1 | 51654 | 218315_s_at | 0.4285 | 0.0001 | |
| GSE45670 | CDK5RAP1 | 51654 | 218315_s_at | 0.3497 | 0.0122 | |
| GSE53622 | CDK5RAP1 | 51654 | 112599 | 0.5586 | 0.0000 | |
| GSE53624 | CDK5RAP1 | 51654 | 112599 | 0.7440 | 0.0000 | |
| GSE63941 | CDK5RAP1 | 51654 | 218315_s_at | 0.3033 | 0.3834 | |
| GSE77861 | CDK5RAP1 | 51654 | 218315_s_at | 0.4218 | 0.0683 | |
| GSE97050 | CDK5RAP1 | 51654 | A_23_P257278 | 0.3823 | 0.2688 | |
| SRP007169 | CDK5RAP1 | 51654 | RNAseq | 0.6249 | 0.1004 | |
| SRP008496 | CDK5RAP1 | 51654 | RNAseq | 0.3776 | 0.1929 | |
| SRP064894 | CDK5RAP1 | 51654 | RNAseq | 0.9866 | 0.0000 | |
| SRP133303 | CDK5RAP1 | 51654 | RNAseq | 0.4875 | 0.0000 | |
| SRP159526 | CDK5RAP1 | 51654 | RNAseq | 0.2437 | 0.2122 | |
| SRP193095 | CDK5RAP1 | 51654 | RNAseq | 0.4794 | 0.0000 | |
| SRP219564 | CDK5RAP1 | 51654 | RNAseq | 0.9398 | 0.0275 | |
| TCGA | CDK5RAP1 | 51654 | RNAseq | 0.1226 | 0.0339 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CDK5RAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDK5RAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDK5RAP1 | 51654 | 15 | 0 | 15 | |
| GSE20123 | CDK5RAP1 | 51654 | 15 | 0 | 15 | |
| GSE43470 | CDK5RAP1 | 51654 | 12 | 0 | 31 | |
| GSE46452 | CDK5RAP1 | 51654 | 29 | 0 | 30 | |
| GSE47630 | CDK5RAP1 | 51654 | 24 | 1 | 15 | |
| GSE54993 | CDK5RAP1 | 51654 | 0 | 19 | 51 | |
| GSE54994 | CDK5RAP1 | 51654 | 26 | 1 | 26 | |
| GSE60625 | CDK5RAP1 | 51654 | 0 | 0 | 11 | |
| GSE74703 | CDK5RAP1 | 51654 | 11 | 0 | 25 | |
| GSE74704 | CDK5RAP1 | 51654 | 10 | 0 | 10 | |
| TCGA | CDK5RAP1 | 51654 | 50 | 1 | 45 |
Total number of gains: 192; Total number of losses: 22; Total Number of normals: 274.
Somatic mutations of CDK5RAP1:
Generating mutation plots.
Highly correlated genes for CDK5RAP1:
Showing top 20/1588 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDK5RAP1 | SCO1 | 0.804151 | 3 | 0 | 3 |
| CDK5RAP1 | PET117 | 0.76186 | 4 | 0 | 4 |
| CDK5RAP1 | ZNF707 | 0.750215 | 3 | 0 | 3 |
| CDK5RAP1 | ZNF622 | 0.729999 | 4 | 0 | 4 |
| CDK5RAP1 | PDRG1 | 0.729793 | 6 | 0 | 5 |
| CDK5RAP1 | WIPI2 | 0.717946 | 3 | 0 | 3 |
| CDK5RAP1 | DHRS13 | 0.716077 | 3 | 0 | 3 |
| CDK5RAP1 | TDRD5 | 0.714879 | 4 | 0 | 3 |
| CDK5RAP1 | MRPS5 | 0.705329 | 3 | 0 | 3 |
| CDK5RAP1 | DNTTIP1 | 0.696701 | 6 | 0 | 4 |
| CDK5RAP1 | HSD17B6 | 0.695273 | 4 | 0 | 4 |
| CDK5RAP1 | SPRED1 | 0.694345 | 3 | 0 | 3 |
| CDK5RAP1 | YTHDF1 | 0.689544 | 11 | 0 | 10 |
| CDK5RAP1 | KIF3B | 0.689266 | 11 | 0 | 10 |
| CDK5RAP1 | CCM2 | 0.689072 | 7 | 0 | 7 |
| CDK5RAP1 | PSMA7 | 0.688393 | 10 | 0 | 8 |
| CDK5RAP1 | EBNA1BP2 | 0.686825 | 3 | 0 | 3 |
| CDK5RAP1 | USP42 | 0.68447 | 6 | 0 | 6 |
| CDK5RAP1 | THEM4 | 0.682965 | 4 | 0 | 3 |
| CDK5RAP1 | ACTR5 | 0.682864 | 11 | 0 | 11 |
For details and further investigation, click here
