| Full name: PHD and ring finger domains 1 | Alias Symbol: KIAA1542|PPP1R125 | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 57661 | HGNC ID: HGNC:24351 | Ensembl Gene: ENSG00000070047 | OMIM ID: 611780 |
| Drug and gene relationship at DGIdb | |||
Expression of PHRF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHRF1 | 57661 | 234952_s_at | -0.0463 | 0.9089 | |
| GSE26886 | PHRF1 | 57661 | 234952_s_at | 0.8406 | 0.0000 | |
| GSE45670 | PHRF1 | 57661 | 234952_s_at | 0.0734 | 0.5304 | |
| GSE53622 | PHRF1 | 57661 | 140187 | -0.1651 | 0.0011 | |
| GSE53624 | PHRF1 | 57661 | 140187 | 0.0459 | 0.3917 | |
| GSE63941 | PHRF1 | 57661 | 234952_s_at | -0.4551 | 0.1368 | |
| GSE77861 | PHRF1 | 57661 | 234952_s_at | 0.0775 | 0.7214 | |
| GSE97050 | PHRF1 | 57661 | A_32_P8251 | -0.0572 | 0.8432 | |
| SRP007169 | PHRF1 | 57661 | RNAseq | 0.8441 | 0.1004 | |
| SRP064894 | PHRF1 | 57661 | RNAseq | -0.0933 | 0.5729 | |
| SRP133303 | PHRF1 | 57661 | RNAseq | -0.0333 | 0.8062 | |
| SRP159526 | PHRF1 | 57661 | RNAseq | -0.3006 | 0.2425 | |
| SRP193095 | PHRF1 | 57661 | RNAseq | 0.3664 | 0.0109 | |
| SRP219564 | PHRF1 | 57661 | RNAseq | -0.1548 | 0.6336 | |
| TCGA | PHRF1 | 57661 | RNAseq | -0.0246 | 0.5891 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PHRF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHRF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHRF1 | 57661 | 1 | 11 | 18 | |
| GSE20123 | PHRF1 | 57661 | 1 | 12 | 17 | |
| GSE43470 | PHRF1 | 57661 | 1 | 10 | 32 | |
| GSE46452 | PHRF1 | 57661 | 7 | 8 | 44 | |
| GSE47630 | PHRF1 | 57661 | 4 | 12 | 24 | |
| GSE54993 | PHRF1 | 57661 | 3 | 1 | 66 | |
| GSE54994 | PHRF1 | 57661 | 1 | 12 | 40 | |
| GSE60625 | PHRF1 | 57661 | 0 | 0 | 11 | |
| GSE74703 | PHRF1 | 57661 | 1 | 8 | 27 | |
| GSE74704 | PHRF1 | 57661 | 0 | 8 | 12 | |
| TCGA | PHRF1 | 57661 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 120; Total Number of normals: 341.
Somatic mutations of PHRF1:
Generating mutation plots.
Highly correlated genes for PHRF1:
Showing top 20/283 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHRF1 | INO80E | 0.84893 | 3 | 0 | 3 |
| PHRF1 | CIC | 0.81118 | 3 | 0 | 3 |
| PHRF1 | ZCCHC17 | 0.785453 | 3 | 0 | 3 |
| PHRF1 | LINGO1 | 0.770285 | 3 | 0 | 3 |
| PHRF1 | SORBS3 | 0.767774 | 3 | 0 | 3 |
| PHRF1 | GLI3 | 0.767362 | 3 | 0 | 3 |
| PHRF1 | RGS19 | 0.761892 | 3 | 0 | 3 |
| PHRF1 | RHBDF2 | 0.759575 | 3 | 0 | 3 |
| PHRF1 | MYH10 | 0.759219 | 3 | 0 | 3 |
| PHRF1 | GRIN3B | 0.757436 | 3 | 0 | 3 |
| PHRF1 | RAB11B | 0.7573 | 3 | 0 | 3 |
| PHRF1 | IMPDH1 | 0.75443 | 3 | 0 | 3 |
| PHRF1 | MRC2 | 0.752875 | 3 | 0 | 3 |
| PHRF1 | B3GNT9 | 0.75049 | 3 | 0 | 3 |
| PHRF1 | BSN | 0.747894 | 3 | 0 | 3 |
| PHRF1 | LIMK1 | 0.745812 | 4 | 0 | 4 |
| PHRF1 | PPHLN1 | 0.745032 | 3 | 0 | 3 |
| PHRF1 | BCORL1 | 0.74479 | 3 | 0 | 3 |
| PHRF1 | MEF2A | 0.743417 | 3 | 0 | 3 |
| PHRF1 | STC2 | 0.736545 | 3 | 0 | 3 |
For details and further investigation, click here
