| Full name: NADH:ubiquinone oxidoreductase complex assembly factor 1 | Alias Symbol: CIA30|CGI-65 | ||
| Type: protein-coding gene | Cytoband: 15q15.1 | ||
| Entrez ID: 51103 | HGNC ID: HGNC:18828 | Ensembl Gene: ENSG00000137806 | OMIM ID: 606934 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NDUFAF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFAF1 | 51103 | 204125_at | -0.6049 | 0.2400 | |
| GSE20347 | NDUFAF1 | 51103 | 204125_at | -0.5215 | 0.0000 | |
| GSE23400 | NDUFAF1 | 51103 | 204125_at | -0.2935 | 0.0000 | |
| GSE26886 | NDUFAF1 | 51103 | 204125_at | -0.8012 | 0.0021 | |
| GSE29001 | NDUFAF1 | 51103 | 204125_at | -0.7120 | 0.0050 | |
| GSE38129 | NDUFAF1 | 51103 | 204125_at | -0.4119 | 0.0002 | |
| GSE45670 | NDUFAF1 | 51103 | 204125_at | -0.2698 | 0.1532 | |
| GSE53622 | NDUFAF1 | 51103 | 3167 | -0.6399 | 0.0000 | |
| GSE53624 | NDUFAF1 | 51103 | 3167 | -0.5643 | 0.0000 | |
| GSE63941 | NDUFAF1 | 51103 | 204125_at | -0.7584 | 0.1057 | |
| GSE77861 | NDUFAF1 | 51103 | 204125_at | -0.6138 | 0.0761 | |
| GSE97050 | NDUFAF1 | 51103 | A_23_P26254 | -0.1558 | 0.4629 | |
| SRP007169 | NDUFAF1 | 51103 | RNAseq | -1.5601 | 0.0005 | |
| SRP008496 | NDUFAF1 | 51103 | RNAseq | -1.4316 | 0.0000 | |
| SRP064894 | NDUFAF1 | 51103 | RNAseq | -0.4424 | 0.0031 | |
| SRP133303 | NDUFAF1 | 51103 | RNAseq | -0.2455 | 0.1289 | |
| SRP159526 | NDUFAF1 | 51103 | RNAseq | -0.2754 | 0.4634 | |
| SRP193095 | NDUFAF1 | 51103 | RNAseq | -0.5036 | 0.0000 | |
| SRP219564 | NDUFAF1 | 51103 | RNAseq | -0.7192 | 0.0080 | |
| TCGA | NDUFAF1 | 51103 | RNAseq | -0.1348 | 0.0442 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NDUFAF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFAF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFAF1 | 51103 | 3 | 6 | 21 | |
| GSE20123 | NDUFAF1 | 51103 | 3 | 6 | 21 | |
| GSE43470 | NDUFAF1 | 51103 | 4 | 6 | 33 | |
| GSE46452 | NDUFAF1 | 51103 | 3 | 7 | 49 | |
| GSE47630 | NDUFAF1 | 51103 | 8 | 11 | 21 | |
| GSE54993 | NDUFAF1 | 51103 | 4 | 6 | 60 | |
| GSE54994 | NDUFAF1 | 51103 | 5 | 7 | 41 | |
| GSE60625 | NDUFAF1 | 51103 | 4 | 0 | 7 | |
| GSE74703 | NDUFAF1 | 51103 | 4 | 5 | 27 | |
| GSE74704 | NDUFAF1 | 51103 | 2 | 4 | 14 | |
| TCGA | NDUFAF1 | 51103 | 11 | 18 | 67 |
Total number of gains: 51; Total number of losses: 76; Total Number of normals: 361.
Somatic mutations of NDUFAF1:
Generating mutation plots.
Highly correlated genes for NDUFAF1:
Showing top 20/1218 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFAF1 | PEX2 | 0.759028 | 3 | 0 | 3 |
| NDUFAF1 | ACTR2 | 0.746951 | 3 | 0 | 3 |
| NDUFAF1 | IMPACT | 0.745802 | 3 | 0 | 3 |
| NDUFAF1 | GBP6 | 0.725769 | 4 | 0 | 4 |
| NDUFAF1 | CHP1 | 0.7106 | 10 | 0 | 10 |
| NDUFAF1 | BBS4 | 0.706722 | 3 | 0 | 3 |
| NDUFAF1 | ZNF823 | 0.701404 | 6 | 0 | 6 |
| NDUFAF1 | CCNYL1 | 0.69969 | 5 | 0 | 4 |
| NDUFAF1 | SLC22A15 | 0.695248 | 4 | 0 | 3 |
| NDUFAF1 | VPS39 | 0.693809 | 3 | 0 | 3 |
| NDUFAF1 | HDHD2 | 0.692142 | 5 | 0 | 5 |
| NDUFAF1 | FAM214A | 0.689487 | 6 | 0 | 6 |
| NDUFAF1 | ULK3 | 0.68941 | 7 | 0 | 7 |
| NDUFAF1 | MRPL46 | 0.688349 | 8 | 0 | 8 |
| NDUFAF1 | RAB11A | 0.685467 | 11 | 0 | 9 |
| NDUFAF1 | RNFT1 | 0.682016 | 3 | 0 | 3 |
| NDUFAF1 | BRK1 | 0.680945 | 7 | 0 | 6 |
| NDUFAF1 | GMPPB | 0.678737 | 3 | 0 | 3 |
| NDUFAF1 | PIAS2 | 0.677763 | 3 | 0 | 3 |
| NDUFAF1 | KBTBD3 | 0.677467 | 3 | 0 | 3 |
For details and further investigation, click here
