| Full name: PHD finger protein 23 | Alias Symbol: MGC2941|FLJ16355 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 79142 | HGNC ID: HGNC:28428 | Ensembl Gene: ENSG00000040633 | OMIM ID: 612910 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PHF23:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHF23 | 79142 | 223081_at | 0.1929 | 0.6137 | |
| GSE26886 | PHF23 | 79142 | 223081_at | -0.1584 | 0.4121 | |
| GSE45670 | PHF23 | 79142 | 223081_at | -0.0010 | 0.9954 | |
| GSE53622 | PHF23 | 79142 | 25882 | -0.1414 | 0.0699 | |
| GSE53624 | PHF23 | 79142 | 139376 | -0.2538 | 0.0001 | |
| GSE63941 | PHF23 | 79142 | 223081_at | -0.0070 | 0.9814 | |
| GSE77861 | PHF23 | 79142 | 223081_at | 0.1094 | 0.4733 | |
| GSE97050 | PHF23 | 79142 | A_24_P5550 | 0.1150 | 0.7525 | |
| SRP007169 | PHF23 | 79142 | RNAseq | -1.0742 | 0.0121 | |
| SRP008496 | PHF23 | 79142 | RNAseq | -0.9263 | 0.0001 | |
| SRP064894 | PHF23 | 79142 | RNAseq | -0.3351 | 0.0666 | |
| SRP133303 | PHF23 | 79142 | RNAseq | -0.3435 | 0.0319 | |
| SRP159526 | PHF23 | 79142 | RNAseq | -0.3041 | 0.3163 | |
| SRP193095 | PHF23 | 79142 | RNAseq | -0.4064 | 0.0008 | |
| SRP219564 | PHF23 | 79142 | RNAseq | -0.2344 | 0.5559 | |
| TCGA | PHF23 | 79142 | RNAseq | 0.0882 | 0.1137 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PHF23 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHF23:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHF23 | 79142 | 4 | 2 | 24 | |
| GSE20123 | PHF23 | 79142 | 4 | 3 | 23 | |
| GSE43470 | PHF23 | 79142 | 1 | 4 | 38 | |
| GSE46452 | PHF23 | 79142 | 34 | 1 | 24 | |
| GSE47630 | PHF23 | 79142 | 7 | 1 | 32 | |
| GSE54993 | PHF23 | 79142 | 4 | 3 | 63 | |
| GSE54994 | PHF23 | 79142 | 5 | 8 | 40 | |
| GSE60625 | PHF23 | 79142 | 4 | 0 | 7 | |
| GSE74703 | PHF23 | 79142 | 1 | 2 | 33 | |
| GSE74704 | PHF23 | 79142 | 2 | 1 | 17 | |
| TCGA | PHF23 | 79142 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 46; Total Number of normals: 359.
Somatic mutations of PHF23:
Generating mutation plots.
Highly correlated genes for PHF23:
Showing top 20/184 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHF23 | AKT2 | 0.776613 | 3 | 0 | 3 |
| PHF23 | SH3BGRL3 | 0.774513 | 3 | 0 | 3 |
| PHF23 | SUGP1 | 0.771113 | 3 | 0 | 3 |
| PHF23 | RHOG | 0.76096 | 3 | 0 | 3 |
| PHF23 | MAPK8IP3 | 0.745795 | 3 | 0 | 3 |
| PHF23 | KCNK6 | 0.743437 | 3 | 0 | 3 |
| PHF23 | PIAS3 | 0.742202 | 4 | 0 | 3 |
| PHF23 | BCL2L1 | 0.729091 | 3 | 0 | 3 |
| PHF23 | ELOVL1 | 0.726138 | 3 | 0 | 3 |
| PHF23 | RNF187 | 0.723954 | 3 | 0 | 3 |
| PHF23 | PA2G4 | 0.723648 | 3 | 0 | 3 |
| PHF23 | GTPBP2 | 0.722256 | 3 | 0 | 3 |
| PHF23 | LSR | 0.720537 | 3 | 0 | 3 |
| PHF23 | MFSD5 | 0.717944 | 3 | 0 | 3 |
| PHF23 | VPS25 | 0.711253 | 3 | 0 | 3 |
| PHF23 | E2F3 | 0.707625 | 3 | 0 | 3 |
| PHF23 | NIT1 | 0.707235 | 3 | 0 | 3 |
| PHF23 | PPP2R2A | 0.706903 | 3 | 0 | 3 |
| PHF23 | PRRC2C | 0.702784 | 3 | 0 | 3 |
| PHF23 | RNASEK | 0.701664 | 3 | 0 | 3 |
For details and further investigation, click here
