| Full name: proliferation-associated 2G4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q13.2 | ||
| Entrez ID: 5036 | HGNC ID: HGNC:8550 | Ensembl Gene: ENSG00000170515 | OMIM ID: 602145 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PA2G4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PA2G4 | 5036 | 208676_s_at | 0.4589 | 0.3020 | |
| GSE20347 | PA2G4 | 5036 | 208676_s_at | 0.1040 | 0.4729 | |
| GSE23400 | PA2G4 | 5036 | 208676_s_at | 0.1748 | 0.0136 | |
| GSE26886 | PA2G4 | 5036 | 208676_s_at | 0.0265 | 0.8799 | |
| GSE29001 | PA2G4 | 5036 | 208676_s_at | -0.1176 | 0.5843 | |
| GSE38129 | PA2G4 | 5036 | 208676_s_at | 0.2888 | 0.0244 | |
| GSE45670 | PA2G4 | 5036 | 208676_s_at | 0.1939 | 0.1475 | |
| GSE53622 | PA2G4 | 5036 | 14696 | -0.0138 | 0.8508 | |
| GSE53624 | PA2G4 | 5036 | 14696 | 0.3424 | 0.0000 | |
| GSE63941 | PA2G4 | 5036 | 208676_s_at | 1.2699 | 0.0003 | |
| GSE77861 | PA2G4 | 5036 | 208676_s_at | 0.1362 | 0.5904 | |
| GSE97050 | PA2G4 | 5036 | A_33_P3227209 | 0.1803 | 0.5147 | |
| SRP007169 | PA2G4 | 5036 | RNAseq | 0.5241 | 0.1081 | |
| SRP008496 | PA2G4 | 5036 | RNAseq | 0.4908 | 0.0381 | |
| SRP064894 | PA2G4 | 5036 | RNAseq | 0.0072 | 0.9641 | |
| SRP133303 | PA2G4 | 5036 | RNAseq | 0.3902 | 0.0723 | |
| SRP159526 | PA2G4 | 5036 | RNAseq | -0.1896 | 0.1699 | |
| SRP193095 | PA2G4 | 5036 | RNAseq | 0.0361 | 0.7967 | |
| SRP219564 | PA2G4 | 5036 | RNAseq | 0.3839 | 0.3882 | |
| TCGA | PA2G4 | 5036 | RNAseq | 0.1863 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PA2G4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PA2G4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PA2G4 | 5036 | 7 | 2 | 21 | |
| GSE20123 | PA2G4 | 5036 | 7 | 1 | 22 | |
| GSE43470 | PA2G4 | 5036 | 4 | 0 | 39 | |
| GSE46452 | PA2G4 | 5036 | 8 | 1 | 50 | |
| GSE47630 | PA2G4 | 5036 | 10 | 2 | 28 | |
| GSE54993 | PA2G4 | 5036 | 0 | 5 | 65 | |
| GSE54994 | PA2G4 | 5036 | 4 | 1 | 48 | |
| GSE60625 | PA2G4 | 5036 | 0 | 0 | 11 | |
| GSE74703 | PA2G4 | 5036 | 4 | 0 | 32 | |
| GSE74704 | PA2G4 | 5036 | 4 | 1 | 15 | |
| TCGA | PA2G4 | 5036 | 15 | 10 | 71 |
Total number of gains: 63; Total number of losses: 23; Total Number of normals: 402.
Somatic mutations of PA2G4:
Generating mutation plots.
Highly correlated genes for PA2G4:
Showing top 20/776 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PA2G4 | CRTC2 | 0.821943 | 3 | 0 | 3 |
| PA2G4 | PMF1 | 0.779836 | 3 | 0 | 3 |
| PA2G4 | PLCB2 | 0.774413 | 3 | 0 | 3 |
| PA2G4 | PRR12 | 0.7686 | 3 | 0 | 3 |
| PA2G4 | GGN | 0.760466 | 3 | 0 | 3 |
| PA2G4 | PPIE | 0.743461 | 3 | 0 | 3 |
| PA2G4 | ZNF771 | 0.740487 | 3 | 0 | 3 |
| PA2G4 | MED8 | 0.73845 | 3 | 0 | 3 |
| PA2G4 | OPHN1 | 0.736509 | 3 | 0 | 3 |
| PA2G4 | TMEM11 | 0.733455 | 4 | 0 | 3 |
| PA2G4 | SNRPE | 0.732534 | 4 | 0 | 3 |
| PA2G4 | CTF1 | 0.728977 | 4 | 0 | 4 |
| PA2G4 | SPTAN1 | 0.726401 | 4 | 0 | 4 |
| PA2G4 | PHF23 | 0.723648 | 3 | 0 | 3 |
| PA2G4 | WDR5 | 0.71648 | 4 | 0 | 4 |
| PA2G4 | RSRC1 | 0.715355 | 3 | 0 | 3 |
| PA2G4 | DPH7 | 0.715292 | 3 | 0 | 3 |
| PA2G4 | DGKH | 0.710739 | 3 | 0 | 3 |
| PA2G4 | CIC | 0.708422 | 4 | 0 | 3 |
| PA2G4 | MRPL38 | 0.708175 | 4 | 0 | 3 |
For details and further investigation, click here
