| Full name: regulator of G protein signaling 19 | Alias Symbol: GAIP|RGSGAIP | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 10287 | HGNC ID: HGNC:13735 | Ensembl Gene: ENSG00000171700 | OMIM ID: 605071 |
| Drug and gene relationship at DGIdb | |||
Expression of RGS19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RGS19 | 10287 | 204336_s_at | 0.9181 | 0.0517 | |
| GSE20347 | RGS19 | 10287 | 204336_s_at | 0.6976 | 0.0000 | |
| GSE23400 | RGS19 | 10287 | 204336_s_at | 0.4173 | 0.0000 | |
| GSE26886 | RGS19 | 10287 | 204336_s_at | 1.2806 | 0.0000 | |
| GSE29001 | RGS19 | 10287 | 204336_s_at | 0.6409 | 0.0035 | |
| GSE38129 | RGS19 | 10287 | 204336_s_at | 0.7707 | 0.0000 | |
| GSE45670 | RGS19 | 10287 | 204336_s_at | 0.6118 | 0.0028 | |
| GSE53622 | RGS19 | 10287 | 20556 | 0.4879 | 0.0001 | |
| GSE53624 | RGS19 | 10287 | 20556 | 0.9718 | 0.0000 | |
| GSE63941 | RGS19 | 10287 | 204336_s_at | 0.3582 | 0.4362 | |
| GSE77861 | RGS19 | 10287 | 204336_s_at | 0.3535 | 0.1623 | |
| GSE97050 | RGS19 | 10287 | A_33_P3211956 | 0.7895 | 0.1118 | |
| SRP007169 | RGS19 | 10287 | RNAseq | 0.4907 | 0.4171 | |
| SRP008496 | RGS19 | 10287 | RNAseq | 0.6849 | 0.0950 | |
| SRP064894 | RGS19 | 10287 | RNAseq | 1.3508 | 0.0000 | |
| SRP133303 | RGS19 | 10287 | RNAseq | 0.6959 | 0.0004 | |
| SRP159526 | RGS19 | 10287 | RNAseq | 0.1294 | 0.7765 | |
| SRP193095 | RGS19 | 10287 | RNAseq | 0.7344 | 0.0000 | |
| SRP219564 | RGS19 | 10287 | RNAseq | 0.7849 | 0.0611 | |
| TCGA | RGS19 | 10287 | RNAseq | 0.5587 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RGS19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RGS19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RGS19 | 10287 | 13 | 2 | 15 | |
| GSE20123 | RGS19 | 10287 | 13 | 2 | 15 | |
| GSE43470 | RGS19 | 10287 | 11 | 1 | 31 | |
| GSE46452 | RGS19 | 10287 | 35 | 0 | 24 | |
| GSE47630 | RGS19 | 10287 | 25 | 1 | 14 | |
| GSE54993 | RGS19 | 10287 | 0 | 17 | 53 | |
| GSE54994 | RGS19 | 10287 | 29 | 0 | 24 | |
| GSE60625 | RGS19 | 10287 | 0 | 0 | 11 | |
| GSE74703 | RGS19 | 10287 | 10 | 0 | 26 | |
| GSE74704 | RGS19 | 10287 | 10 | 0 | 10 | |
| TCGA | RGS19 | 10287 | 44 | 4 | 48 |
Total number of gains: 190; Total number of losses: 27; Total Number of normals: 271.
Somatic mutations of RGS19:
Generating mutation plots.
Highly correlated genes for RGS19:
Showing top 20/1924 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RGS19 | ROMO1 | 0.818862 | 3 | 0 | 3 |
| RGS19 | NTPCR | 0.799136 | 4 | 0 | 4 |
| RGS19 | DHRS13 | 0.782852 | 3 | 0 | 3 |
| RGS19 | PHRF1 | 0.761892 | 3 | 0 | 3 |
| RGS19 | NOTCH3 | 0.757827 | 3 | 0 | 3 |
| RGS19 | TDRD5 | 0.745545 | 3 | 0 | 3 |
| RGS19 | PPP1R9B | 0.743793 | 4 | 0 | 4 |
| RGS19 | SSBP4 | 0.735552 | 4 | 0 | 3 |
| RGS19 | HAVCR2 | 0.73085 | 3 | 0 | 3 |
| RGS19 | WIPI1 | 0.727291 | 3 | 0 | 3 |
| RGS19 | SEC22C | 0.722056 | 3 | 0 | 3 |
| RGS19 | FAM171B | 0.720009 | 3 | 0 | 3 |
| RGS19 | CCT5 | 0.715375 | 6 | 0 | 6 |
| RGS19 | KTI12 | 0.714616 | 3 | 0 | 3 |
| RGS19 | GLIS2 | 0.713847 | 4 | 0 | 4 |
| RGS19 | FCGR3A | 0.713615 | 3 | 0 | 3 |
| RGS19 | PLA2G7 | 0.713503 | 11 | 0 | 11 |
| RGS19 | BMP2 | 0.712053 | 4 | 0 | 4 |
| RGS19 | MMP12 | 0.710933 | 10 | 0 | 10 |
| RGS19 | ETV6 | 0.709377 | 3 | 0 | 3 |
For details and further investigation, click here
