| Full name: PIH1 domain containing 1 | Alias Symbol: FLJ20643|Pih1 | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 55011 | HGNC ID: HGNC:26075 | Ensembl Gene: ENSG00000104872 | OMIM ID: 611480 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PIH1D1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIH1D1 | 55011 | 217872_at | 0.0075 | 0.9883 | |
| GSE20347 | PIH1D1 | 55011 | 217872_at | -0.3881 | 0.0004 | |
| GSE23400 | PIH1D1 | 55011 | 217872_at | -0.0956 | 0.1013 | |
| GSE26886 | PIH1D1 | 55011 | 217872_at | -0.2054 | 0.3318 | |
| GSE29001 | PIH1D1 | 55011 | 217872_at | -0.2346 | 0.2900 | |
| GSE38129 | PIH1D1 | 55011 | 217872_at | -0.1920 | 0.0201 | |
| GSE45670 | PIH1D1 | 55011 | 217872_at | -0.0919 | 0.5348 | |
| GSE53622 | PIH1D1 | 55011 | 18987 | -0.1785 | 0.0000 | |
| GSE53624 | PIH1D1 | 55011 | 18987 | 0.0105 | 0.8626 | |
| GSE63941 | PIH1D1 | 55011 | 217872_at | 1.1736 | 0.0052 | |
| GSE77861 | PIH1D1 | 55011 | 217872_at | -0.1743 | 0.2332 | |
| GSE97050 | PIH1D1 | 55011 | A_33_P3255409 | -0.0410 | 0.8589 | |
| SRP007169 | PIH1D1 | 55011 | RNAseq | -1.1225 | 0.0014 | |
| SRP008496 | PIH1D1 | 55011 | RNAseq | -1.1836 | 0.0000 | |
| SRP064894 | PIH1D1 | 55011 | RNAseq | 0.4517 | 0.1432 | |
| SRP133303 | PIH1D1 | 55011 | RNAseq | -0.4648 | 0.0177 | |
| SRP159526 | PIH1D1 | 55011 | RNAseq | 0.0155 | 0.9545 | |
| SRP193095 | PIH1D1 | 55011 | RNAseq | -0.3692 | 0.0003 | |
| SRP219564 | PIH1D1 | 55011 | RNAseq | -0.3477 | 0.1230 | |
| TCGA | PIH1D1 | 55011 | RNAseq | 0.0157 | 0.7687 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by PIH1D1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIH1D1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIH1D1 | 55011 | 4 | 4 | 22 | |
| GSE20123 | PIH1D1 | 55011 | 4 | 3 | 23 | |
| GSE43470 | PIH1D1 | 55011 | 4 | 11 | 28 | |
| GSE46452 | PIH1D1 | 55011 | 45 | 1 | 13 | |
| GSE47630 | PIH1D1 | 55011 | 10 | 6 | 24 | |
| GSE54993 | PIH1D1 | 55011 | 17 | 4 | 49 | |
| GSE54994 | PIH1D1 | 55011 | 4 | 14 | 35 | |
| GSE60625 | PIH1D1 | 55011 | 9 | 0 | 2 | |
| GSE74703 | PIH1D1 | 55011 | 4 | 7 | 25 | |
| GSE74704 | PIH1D1 | 55011 | 4 | 1 | 15 | |
| TCGA | PIH1D1 | 55011 | 14 | 19 | 63 |
Total number of gains: 119; Total number of losses: 70; Total Number of normals: 299.
Somatic mutations of PIH1D1:
Generating mutation plots.
Highly correlated genes for PIH1D1:
Showing top 20/76 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIH1D1 | GPR26 | 0.683079 | 3 | 0 | 3 |
| PIH1D1 | STAP2 | 0.64919 | 3 | 0 | 3 |
| PIH1D1 | CLUL1 | 0.636372 | 3 | 0 | 3 |
| PIH1D1 | CD52 | 0.633717 | 5 | 0 | 4 |
| PIH1D1 | OXER1 | 0.620939 | 4 | 0 | 3 |
| PIH1D1 | STH | 0.620528 | 3 | 0 | 3 |
| PIH1D1 | CLVS1 | 0.607744 | 3 | 0 | 3 |
| PIH1D1 | TRAPPC6A | 0.60605 | 4 | 0 | 3 |
| PIH1D1 | STX19 | 0.596719 | 3 | 0 | 3 |
| PIH1D1 | SOHLH1 | 0.595313 | 3 | 0 | 3 |
| PIH1D1 | RPL18 | 0.592047 | 9 | 0 | 7 |
| PIH1D1 | CCDC130 | 0.589965 | 3 | 0 | 3 |
| PIH1D1 | CCDC57 | 0.588973 | 4 | 0 | 3 |
| PIH1D1 | BEST4 | 0.587316 | 3 | 0 | 3 |
| PIH1D1 | AKAP1 | 0.586488 | 3 | 0 | 3 |
| PIH1D1 | ZNF341 | 0.582603 | 4 | 0 | 3 |
| PIH1D1 | CD247 | 0.578749 | 3 | 0 | 3 |
| PIH1D1 | TECPR1 | 0.574907 | 4 | 0 | 3 |
| PIH1D1 | PPP1R27 | 0.573473 | 3 | 0 | 3 |
| PIH1D1 | PPP2R1A | 0.569416 | 11 | 0 | 7 |
For details and further investigation, click here
