| Full name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12p12.3 | ||
| Entrez ID: 5288 | HGNC ID: HGNC:8973 | Ensembl Gene: ENSG00000139144 | OMIM ID: 609001 |
| Drug and gene relationship at DGIdb | |||
Expression of PIK3C2G:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIK3C2G | 5288 | 215129_at | -1.1009 | 0.0506 | |
| GSE20347 | PIK3C2G | 5288 | 215129_at | -0.7624 | 0.0000 | |
| GSE23400 | PIK3C2G | 5288 | 215129_at | -0.1587 | 0.0000 | |
| GSE26886 | PIK3C2G | 5288 | 215129_at | -1.3661 | 0.0000 | |
| GSE29001 | PIK3C2G | 5288 | 215129_at | -0.5285 | 0.0647 | |
| GSE38129 | PIK3C2G | 5288 | 215129_at | -1.0032 | 0.0000 | |
| GSE45670 | PIK3C2G | 5288 | 215129_at | -1.2484 | 0.0003 | |
| GSE53622 | PIK3C2G | 5288 | 68967 | -2.3813 | 0.0000 | |
| GSE53624 | PIK3C2G | 5288 | 68967 | -3.4735 | 0.0000 | |
| GSE63941 | PIK3C2G | 5288 | 215129_at | 0.5477 | 0.3998 | |
| GSE77861 | PIK3C2G | 5288 | 215129_at | -0.5796 | 0.0111 | |
| SRP007169 | PIK3C2G | 5288 | RNAseq | -3.2657 | 0.0000 | |
| SRP008496 | PIK3C2G | 5288 | RNAseq | -2.9610 | 0.0000 | |
| SRP064894 | PIK3C2G | 5288 | RNAseq | -2.6399 | 0.0000 | |
| SRP133303 | PIK3C2G | 5288 | RNAseq | -0.7286 | 0.4053 | |
| SRP159526 | PIK3C2G | 5288 | RNAseq | -3.4062 | 0.0000 | |
| SRP193095 | PIK3C2G | 5288 | RNAseq | -1.2456 | 0.0185 | |
| TCGA | PIK3C2G | 5288 | RNAseq | -1.8625 | 0.0010 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by PIK3C2G expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIK3C2G:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIK3C2G | 5288 | 7 | 2 | 21 | |
| GSE20123 | PIK3C2G | 5288 | 7 | 2 | 21 | |
| GSE43470 | PIK3C2G | 5288 | 8 | 4 | 31 | |
| GSE46452 | PIK3C2G | 5288 | 10 | 1 | 48 | |
| GSE47630 | PIK3C2G | 5288 | 14 | 2 | 24 | |
| GSE54993 | PIK3C2G | 5288 | 1 | 9 | 60 | |
| GSE54994 | PIK3C2G | 5288 | 11 | 2 | 40 | |
| GSE60625 | PIK3C2G | 5288 | 0 | 1 | 10 | |
| GSE74703 | PIK3C2G | 5288 | 8 | 3 | 25 | |
| GSE74704 | PIK3C2G | 5288 | 6 | 1 | 13 | |
| TCGA | PIK3C2G | 5288 | 42 | 7 | 47 |
Total number of gains: 114; Total number of losses: 34; Total Number of normals: 340.
Somatic mutations of PIK3C2G:
Generating mutation plots.
Highly correlated genes for PIK3C2G:
Showing top 20/1200 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIK3C2G | SMIM14 | 0.765552 | 6 | 0 | 6 |
| PIK3C2G | STRADB | 0.756599 | 6 | 0 | 6 |
| PIK3C2G | SAMD5 | 0.755942 | 6 | 0 | 6 |
| PIK3C2G | FCHO2 | 0.732322 | 6 | 0 | 6 |
| PIK3C2G | ZNF416 | 0.727592 | 3 | 0 | 3 |
| PIK3C2G | GBP6 | 0.727356 | 4 | 0 | 4 |
| PIK3C2G | RBM20 | 0.722242 | 4 | 0 | 4 |
| PIK3C2G | BBOX1 | 0.721467 | 10 | 0 | 8 |
| PIK3C2G | WNK4 | 0.720035 | 5 | 0 | 5 |
| PIK3C2G | ST6GALNAC1 | 0.714011 | 6 | 0 | 6 |
| PIK3C2G | KIAA1211L | 0.711806 | 7 | 0 | 7 |
| PIK3C2G | DLG2 | 0.708524 | 9 | 0 | 9 |
| PIK3C2G | ZNF662 | 0.708517 | 6 | 0 | 6 |
| PIK3C2G | PAQR8 | 0.701961 | 7 | 0 | 6 |
| PIK3C2G | CTTNBP2 | 0.701626 | 6 | 0 | 6 |
| PIK3C2G | HCG22 | 0.701464 | 6 | 0 | 6 |
| PIK3C2G | STXBP5 | 0.701454 | 6 | 0 | 6 |
| PIK3C2G | MACC1 | 0.698111 | 5 | 0 | 5 |
| PIK3C2G | KIAA2026 | 0.696288 | 4 | 0 | 4 |
| PIK3C2G | FAM3D | 0.6956 | 6 | 0 | 6 |
For details and further investigation, click here
