| Full name: phosphoinositide-3-kinase interacting protein 1 | Alias Symbol: HGFL|MGC17330|TrIP | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 113791 | HGNC ID: HGNC:24942 | Ensembl Gene: ENSG00000100100 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PIK3IP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIK3IP1 | 113791 | 221756_at | -0.4507 | 0.5824 | |
| GSE20347 | PIK3IP1 | 113791 | 221756_at | 0.0292 | 0.8910 | |
| GSE23400 | PIK3IP1 | 113791 | 221756_at | -0.2354 | 0.0002 | |
| GSE26886 | PIK3IP1 | 113791 | 221756_at | -0.1870 | 0.5835 | |
| GSE29001 | PIK3IP1 | 113791 | 221756_at | -0.4091 | 0.0370 | |
| GSE38129 | PIK3IP1 | 113791 | 221756_at | -0.2480 | 0.1244 | |
| GSE45670 | PIK3IP1 | 113791 | 221756_at | -0.3033 | 0.2402 | |
| GSE53622 | PIK3IP1 | 113791 | 61761 | -0.1231 | 0.1164 | |
| GSE53624 | PIK3IP1 | 113791 | 90829 | -0.6210 | 0.0000 | |
| GSE63941 | PIK3IP1 | 113791 | 221756_at | -1.8164 | 0.0021 | |
| GSE77861 | PIK3IP1 | 113791 | 221756_at | 0.0714 | 0.8022 | |
| GSE97050 | PIK3IP1 | 113791 | A_23_P109488 | -0.0370 | 0.8614 | |
| SRP007169 | PIK3IP1 | 113791 | RNAseq | -1.2284 | 0.0231 | |
| SRP008496 | PIK3IP1 | 113791 | RNAseq | -0.8383 | 0.0689 | |
| SRP064894 | PIK3IP1 | 113791 | RNAseq | -0.3472 | 0.1875 | |
| SRP133303 | PIK3IP1 | 113791 | RNAseq | -0.3935 | 0.0312 | |
| SRP159526 | PIK3IP1 | 113791 | RNAseq | -1.0017 | 0.0949 | |
| SRP193095 | PIK3IP1 | 113791 | RNAseq | -0.4799 | 0.0265 | |
| SRP219564 | PIK3IP1 | 113791 | RNAseq | -0.1467 | 0.6548 | |
| TCGA | PIK3IP1 | 113791 | RNAseq | -0.0687 | 0.4431 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PIK3IP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIK3IP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIK3IP1 | 113791 | 4 | 5 | 21 | |
| GSE20123 | PIK3IP1 | 113791 | 4 | 4 | 22 | |
| GSE43470 | PIK3IP1 | 113791 | 4 | 5 | 34 | |
| GSE46452 | PIK3IP1 | 113791 | 31 | 1 | 27 | |
| GSE47630 | PIK3IP1 | 113791 | 8 | 5 | 27 | |
| GSE54993 | PIK3IP1 | 113791 | 3 | 6 | 61 | |
| GSE54994 | PIK3IP1 | 113791 | 12 | 7 | 34 | |
| GSE60625 | PIK3IP1 | 113791 | 5 | 0 | 6 | |
| GSE74703 | PIK3IP1 | 113791 | 4 | 5 | 27 | |
| GSE74704 | PIK3IP1 | 113791 | 1 | 1 | 18 | |
| TCGA | PIK3IP1 | 113791 | 27 | 15 | 54 |
Total number of gains: 103; Total number of losses: 54; Total Number of normals: 331.
Somatic mutations of PIK3IP1:
Generating mutation plots.
Highly correlated genes for PIK3IP1:
Showing top 20/97 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIK3IP1 | ZNF16 | 0.694348 | 3 | 0 | 3 |
| PIK3IP1 | ADD3 | 0.620552 | 3 | 0 | 3 |
| PIK3IP1 | ZNF132 | 0.613543 | 3 | 0 | 3 |
| PIK3IP1 | MDGA1 | 0.611729 | 3 | 0 | 3 |
| PIK3IP1 | TMEM176A | 0.609241 | 4 | 0 | 3 |
| PIK3IP1 | ARHGEF6 | 0.607237 | 5 | 0 | 3 |
| PIK3IP1 | S1PR1 | 0.606867 | 4 | 0 | 3 |
| PIK3IP1 | PLCL2 | 0.604033 | 4 | 0 | 3 |
| PIK3IP1 | ELAC1 | 0.601416 | 3 | 0 | 3 |
| PIK3IP1 | STAT5A | 0.600761 | 4 | 0 | 3 |
| PIK3IP1 | HEIH | 0.592969 | 3 | 0 | 3 |
| PIK3IP1 | RPS6KA2 | 0.591682 | 5 | 0 | 4 |
| PIK3IP1 | IKZF1 | 0.590395 | 4 | 0 | 3 |
| PIK3IP1 | MRVI1 | 0.580114 | 4 | 0 | 4 |
| PIK3IP1 | MFSD1 | 0.576661 | 4 | 0 | 3 |
| PIK3IP1 | TMEM140 | 0.575651 | 4 | 0 | 3 |
| PIK3IP1 | YPEL2 | 0.573759 | 6 | 0 | 4 |
| PIK3IP1 | LRRK2 | 0.573555 | 4 | 0 | 3 |
| PIK3IP1 | TP53INP1 | 0.571362 | 8 | 0 | 5 |
| PIK3IP1 | ZNF521 | 0.56993 | 4 | 0 | 3 |
For details and further investigation, click here
